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2000cc PMMA Buttock Injections Kit

2000cc PMMA Buttock Injections Kit

PMMA (Artefill/Bellafill-type composition – grey-market buttock kit)

Permanent dermal filler (cosmetic injectable)
  • PMMA microsphere/collagen fillers such as Artecoll/Artefill/Bellafill have been CE Marked and/or FDA Approved as medical devices for specific small Volume facial indications, with a defined 20% PMMA / 80% bovine collagen composition, but these approvals do not extend to high Volume buttock augmentation.
  • The specific “2000cc PMMA buttock injections” kits sold via online aesthetic resellers do not correspond to a clearly identifiable MHRA Authorised medicine or registered UK medical device and provide no verifiable evidence of regulatory approval for gluteal augmentation.
  • Recent peer Reviewed literature and expert opinion in aesthetic and plastic surgery caution against the use of PMMA fillers for buttock augmentation, especially by non Specialists, due to the risk of permanent serious complications and the difficulty of managing adverse outcomes.
  • Potential users are advised to rely on products sourced through licensed medical distributors and to follow national device, drug and professional practice regulations, rather than grey Market kits advertised directly to consumers.
Polymethylmethacrylate (PMMA) microsphere filler for gluteal/buttock augmentation

Description

The “2000cc PMMA Buttock Injections” kit is a high-volume cosmetic product advertised online for buttock augmentation using a permanent filler based on polymethylmethacrylate (PMMA) microspheres suspended in a collagen gel. Ecommerce listings state that PMMA stands for polymethyl-methacrylate, is “also called Artefill”, and that the preparation is composed of 20% tiny PMMA microspheres and 80% collagen, marketed as a safe and permanent solution for gluteal enlargement with 2000cc total volume (1000cc per buttock). This kit is sold through grey-market aesthetic webshops rather than regulated pharmacies and is not an officially recognised or guideline-supported medical product for buttock augmentation; permanent PMMA fillers are generally only approved for limited small-volume facial indications under specific brands and devices.

Bnefits

  • Marketed benefit: substantial increase in buttock volume using injectable filler instead of surgical implants or fat transfer, typically advertised as 1000cc per buttock to achieve a larger and rounder appearance.
  • Marketed benefit: described as permanent or long-lasting because PMMA microspheres are non-resorbable and remain as a scaffold after the bovine collagen carrier has been resorbed and replaced by the patient’s own connective tissue.
  • Marketed benefit: promotional text claims 2000cc PMMA buttock injections can “increase your butt size naturally in weeks” and “help reduce cellulite on thighs and butt”, promising a “round bubble shape” with a “jiggly natural feel”.
  • Based on approved PMMA fillers such as Artefill/Bellafill, the 20% PMMA / 80% collagen composition is known to provide immediate volume from the collagen gel and long-term structural augmentation from the microspheres, which stimulate encapsulation by the patient’s own collagen.
  • From a safety perspective, the permanence of PMMA means any augmentation can last many years, but also that complications (e.g. granulomas, deformity, nodules) may be very difficult or impossible to reverse fully.

Indications

  • Online marketing indication: cosmetic gluteal (buttock) augmentation to increase projection and volume, with typical advertisement of a 2000cc kit used as 1000cc per buttock for a fuller, rounder contour.
  • Online marketing indication: cosmetic body shaping and contour enhancement for patients seeking more prominent buttocks without surgical implants or fat grafting.
  • Online marketing indication: some sellers claim improvement in the appearance of cellulite on the buttocks and thighs, although these claims are not supported by robust clinical trial data.
  • Regulatory context: permanent PMMA collagen fillers such as Artefill/Bellafill are formally approved in some markets only for specific small-volume facial indications (e.g. nasolabial folds, acne scars) and are not approved devices or drugs for large-volume buttock augmentation; use for gluteal injections is off-label and associated with significant safety concerns.

Composition

  • Polymethylmethacrylate (PMMA) microspheres, approximately 20% by volume, in line with the composition of Artefill/Bellafill-type facial fillers (20% PMMA microspheres by volume suspended in collagen gel).
  • Bovine collagen carrier gel, approximately 80% by volume, providing immediate volume and acting as a vehicle for the PMMA microspheres; composition in approved fillers is 3.5% bovine collagen with buffer salts, sodium chloride and lidocaine in water for injection.
  • Local anaesthetic (typically lidocaine 0.3%) is listed in Artefill/Bellafill labelling; grey-market 2000cc kits claim similar composition but do not provide full excipient lists or official product characteristics.
  • Additional excipients (e.g. phosphate buffer, sodium chloride, water for injection) are expected based on labelled PMMA fillers, but precise concentrations in the 2000cc buttock kit are not disclosed by resellers.

Formulation

  • Suspension of smooth, round polymethylmethacrylate microspheres in a bovine collagen gel carrier, designed as a permanent soft-tissue filler.
  • Non-resorbable PMMA microspheres in the 30–50 µm range (based on Artefill/Bellafill data) that remain in the tissue, while the bovine collagen carrier is gradually resorbed and replaced by the patient’s own connective tissue over several months.
  • Sterile injectable gel provided for implantation into soft tissues through needles or cannulas; intended as a single-use implantable product and not to be re-sterilised or reused.
  • High-volume kit format (2000cc total) is intended for deep soft-tissue and subcutaneous deposition in the gluteal region when used as advertised, although such use is not aligned with current safety recommendations from many aesthetic and plastic-surgery specialists.

Packaging

  • Online listings describe a “2000cc KIT = (1000cc in each cheek)” without clearly specifying the number or size of syringes or vials; product pages typically show generic filler and buttock images rather than detailed medical labelling.
  • Kits are marketed as including PMMA filler plus ancillary supplies (e.g. needles, syringes, cannulas and basic consumables), but exact component lists vary by seller and are not standardised.
  • Trade and B2B listings sometimes describe the product generically as “Material: PMMA; Volume: 2000cc; Packaging: Sterile; Needle size: Variable; Storage: Refrigerated” without providing manufacturer name, batch traceability or regulatory markings.
  • Packaging shown on reseller websites resembles cosmetic e-commerce presentation rather than a clearly regulated, tamper-evident medical device or medicinal product package with an approved label and instructions for use.

Usage

  • Large-volume PMMA buttock injections carry significant risk (including infection, granulomas, tissue necrosis and systemic complications) and should not be undertaken outside a fully regulated medical environment; consumer self-use or use by unlicensed injectors is unsafe and strongly discouraged.
  • Permanent PMMA fillers require comprehensive patient assessment, informed consent, awareness of allergy risk to bovine collagen, and specialist training in injection technique and complication management; this is not a procedure that can be safely performed with a mail-order kit.
  • Published medical literature and expert opinion caution against using PMMA fillers for body contouring procedures such as buttock augmentation, especially when performed by non-specialists, due to the potential for permanent serious complications.
  • Patients interested in buttock augmentation should consult a board-certified plastic surgeon or appropriately qualified aesthetic specialist to discuss safer, evidence-based alternatives and the regulatory status of PMMA fillers in their region, rather than purchasing high-volume buttock injection kits from unverified online sellers.
  • Because PMMA is permanent, any decision to implant such filler must be approached with extreme caution; if complications occur, complete removal may be very difficult or impossible, and major reconstructive surgery may be required.

Contraindications

  • Known hypersensitivity or allergy to bovine collagen, PMMA or any component of the filler; approved PMMA collagen fillers require pre-treatment skin testing for bovine collagen sensitivity.
  • History of severe allergic reactions or anaphylaxis to injectable fillers, local anaesthetics or bovine-derived products.
  • Active local infection, inflammation or skin disease at or near the intended injection sites (e.g. cellulitis, abscesses, dermatitis, ulcers or open wounds on the buttocks).
  • Bleeding disorders or current use of significant anticoagulant or antiplatelet therapy when bleeding risk cannot be safely managed.
  • Immunosuppression, poorly controlled diabetes or other serious systemic illnesses that impair wound healing or increase the risk of severe infection or sepsis.
  • Pregnancy or breastfeeding, in which elective permanent cosmetic body-contouring procedures are generally contraindicated.
  • History of keloid or hypertrophic scarring, autoimmune diseases or granulomatous disorders, which may predispose to exaggerated foreign-body responses and granuloma formation.
  • Existing implants, unknown substances or previous large-volume injections in the buttocks that could interact unpredictably with additional permanent filler and complicate imaging and future surgery.
  • Any scenario in which appropriate specialist supervision, sterile operating conditions and emergency support are not available; direct-to-consumer use of 2000cc PMMA buttock kits is particularly unsafe.

Adverse Effects

  • Early local reactions such as pain, swelling, redness, bruising, warmth and itching at injection sites, which may be more pronounced given the very large injection volumes used in gluteal augmentation.
  • Formation of nodules, palpable lumps, contour irregularities and asymmetry; nodules and granulomas are recognised complications of PMMA fillers, and high-volume buttock use increases the difficulty of correction.
  • Foreign-body granulomatous reactions that can present months or years after injection, sometimes requiring long-term medical treatment and/or surgical excision and still potentially leaving permanent deformity.
  • Infection and abscess formation, with risk ranging from superficial skin infection to deep soft-tissue infection and sepsis, particularly when injections are performed in non-sterile environments or by inadequately trained injectors.
  • Filler migration or displacement from the intended site, potentially causing asymmetry, strange contour changes or involvement of unintended tissue planes.
  • Vascular compromise, including inadvertent intravascular injection or compression of critical vessels, with potential for tissue ischaemia and necrosis; such events in the buttock region can be catastrophic and may require urgent surgical intervention.
  • Chronic pain, fibrosis, scarring and long-term textural changes of buttock tissues, which may complicate imaging (e.g. MRI, ultrasound) and future surgical procedures.
  • Systemic complications have been reported in association with permanent fillers and large-volume buttock augmentation, including chronic inflammatory states and metabolic or renal sequelae; management can be complex and prolonged.
  • Psychological and quality-of-life impacts due to persistent pain, disfigurement, fear of long-term health consequences and limited options for reversing the procedure.

Storage Conditions

  • Grey-market listings provide limited information; by analogy with approved PMMA collagen fillers, product should be stored at controlled room or refrigerated temperature as specified on the label, protected from extremes of heat and cold and kept in original, sealed packaging until use.
  • The product must not be used after the labelled expiry date; any syringes or vials that appear damaged, discoloured or compromised should be discarded.
  • Once a sterile syringe or vial is opened, filler should be used immediately for a single patient and any remainder discarded; re-use or re-sterilisation is not appropriate for implantable fillers.
  • Kits should be stored securely and kept out of reach of children and unauthorised persons; permanent injectable fillers should only be accessible within regulated medical environments.

Duration

PMMA microspheres are non-resorbable and intended to provide long-term or effectively permanent volume once encapsulated by the patient\u2019s own connective tissue; the bovine collagen carrier is typically absorbed and replaced over the first few months, but the structural presence of PMMA and associated tissue response can persist for many years.

Onset

Augmentation is immediate due to physical volume of the collagen gel and suspended PMMA microspheres; over 1\u20133 months the temporary collagen carrier is resorbed and replaced by new collagen formed around the microspheres, leading to a more stable long-term augmentation effect.

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