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Cambderm Classic (1x1ml)

Cambderm Classic (1x1ml)

Cambderm

Dermal Filler
  • Classified and supplied as a CE Marked medical device (Legal Category: MD (CE) as per Church Pharmacy product data).
  • Manufactured under Cambridge Biotech’s quality management systems, consistent with international standards for medical device production (e.g. ISO 13485).
  • Hyaluronic acid of non Animal origin with stabilisation and cross Linking processes that comply with applicable safety and performance requirements for injectable dermal fillers in relevant markets.
Cross-linked hyaluronic acid dermal filler

Description

Cambderm Classic (1x1ml) is a CE-marked, cross-linked hyaluronic acid dermal filler of non-animal origin, manufactured using Cambridge Biotech's DXN technology. Designed as a global action filler, it restores facial volume, smooths moderate to deep wrinkles and folds, and enhances facial contours including lips, nose, tear troughs and chin. With a concentration of 20 mg/ml cross-linked HA, Cambderm Classic provides natural-looking, long-lasting results typically maintained for around six to nine months. Supplied as a pre-filled 1 ml syringe with high-quality thin-walled 30G needles, it allows precise, controlled injection and excellent tissue adaptability, delivering subtle yet effective rejuvenation when administered by trained medical professionals.

Bnefits

Not publicly listed

Indications

  • Rejuvenation of the face and lips through soft tissue augmentation.
  • Smoothing of moderate to deep wrinkles and facial lines (e.g. nasolabial folds, marionette lines) in adults.
  • Lip augmentation to enhance volume, definition and symmetry.
  • Non-surgical nose reshaping (rhinoplasty) in suitable patients.
  • Tear trough correction to improve the appearance of under-eye hollows in carefully selected patients.
  • Chin augmentation and contouring to refine facial profile.
  • General volumisation and lifting of ageing skin through subdermal injection of cross-linked HA, when performed by appropriately trained practitioners.
  • Indicated for intradermal or subdermal injection for aesthetic purposes, following the Instructions for Use and local guidelines.

Composition

  • Active ingredient: Cross-linked hyaluronic acid 20 mg/ml (non-animal origin).
  • Cross-linking agent: 1,4-Butanediol diglycidyl ether (BDDE).
  • Form: Sterile, transparent gel implant of stabilised hyaluronic acid.
  • Origin: Non-animal, biosynthetic hyaluronic acid.
  • Other excipients: Buffered physiological saline and minor formulation excipients as per the manufacturer’s IFU (full quantitative composition provided in original product documentation).

Formulation

  • Sterile, apyrogenic, cross-linked hyaluronic acid gel (20 mg/ml) for injection.
  • Pre-filled glass syringe (1 ml) with Luer-lock fitting.
  • Supplied with high-quality, thin-walled 30G needles for intradermal/subdermal injection.
  • Medical device, CE-marked (Legal category: MD (CE) as listed in pharmacy product data).

Packaging

  • 1 x 1 ml pre-filled glass syringe of Cambderm Classic cross-linked hyaluronic acid gel.
  • Typically supplied with 2 x thin-walled 30G needles (needle number may vary by batch or distributor; standard configurations include injection needles suitable for facial aesthetics).
  • Sterile packaging for syringe and needles, with outer carton labelled with product name, batch number, expiry date, and manufacturer details.
  • Intended for single-patient, single-use only; contents of the syringe are sterilised by moist heat according to manufacturer information for the Cambderm range.

Usage

  • For professional use only. Cambderm Classic should be injected only by suitably trained and qualified healthcare professionals experienced in the use of cross-linked hyaluronic acid dermal fillers.
  • Before treatment, take a full medical history, assess indications and contraindications, and obtain informed consent, including discussion of potential adverse effects and downtime.
  • Cleanse and disinfect the treatment area thoroughly according to aseptic technique guidelines.
  • Attach the supplied 30G needle securely to the Luer-lock syringe; expel air bubbles before injection.
  • Inject slowly into the mid to deep dermis or subdermal plane, depending on the indication and treatment area (e.g. mid-dermis for wrinkles, deeper planes for contouring or volumisation), using linear threading, serial puncture or other appropriate techniques.
  • Massage the treated area gently after injection, if required, to ensure even product distribution and smooth contour, avoiding excessive pressure.
  • Do not overcorrect; results should be conservative and natural-looking, with adjustments made at follow-up if necessary.
  • Advise patients to avoid extreme facial movements, strenuous exercise, saunas, sunbeds and alcohol for a short period after treatment, according to standard filler aftercare recommendations.
  • Monitor patients for immediate adverse reactions such as swelling, redness, pain or vascular compromise and manage in accordance with current aesthetic practice guidelines.
  • Discard any unused product and used needles as clinical sharps waste; do not re-sterilise or reuse the syringe or needles.

Contraindications

  • Hypersensitivity to hyaluronic acid, BDDE or any component of the formulation.
  • History of severe allergy or anaphylactic reactions.
  • Active infection, inflammation or skin disease at or near the intended injection site (e.g. herpes simplex, acne, dermatitis).
  • Autoimmune diseases or immune-compromised conditions where injectable implants may pose additional risk, unless the patient is evaluated and cleared by an appropriate specialist.
  • Known tendency to develop hypertrophic scars or keloids in the proposed treatment area.
  • Pregnancy and breastfeeding (use is generally not recommended due to lack of safety data).
  • Patients under 18 years of age.
  • Concurrent use with other dermal fillers or implants in the same site where interactions are unknown or may cause complications, unless the practitioner has appropriate expertise and justification.

Adverse Effects

  • Common, usually transient injection-related reactions: redness, swelling, pain, tenderness, bruising, itching or slight discolouration at the injection site.
  • Nodules, lumps or unevenness in the treated area, typically related to injection depth or product placement.
  • Temporary changes in sensation such as numbness or tingling.
  • Infection at the injection site if aseptic technique is not strictly followed.
  • Delayed inflammatory reactions or granuloma formation, which may require medical management.
  • Vascular occlusion or compromise (rare but serious), presenting with blanching, severe pain or tissue ischaemia; this is a medical emergency requiring immediate intervention according to current hyaluronidase and vascular complication protocols.
  • Allergic or hypersensitivity reactions, which may be immediate or delayed.
  • Any suspected serious adverse reaction should be documented and reported according to local pharmacovigilance/medical device vigilance requirements.

Storage Conditions

  • Store in the original packaging at a controlled room temperature, typically between 2°C and 25°C (or as specified in the IFU), away from direct sunlight.
  • Do not freeze; freezing can damage the hyaluronic acid gel structure and compromise product performance.
  • Protect from excessive heat or temperature fluctuations.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the pack, and do not use if the blister or syringe packaging is damaged or previously opened.

Duration

Typical aesthetic results last approximately 6\u20139 months, varying by treatment area, injection technique, patient metabolism and lifestyle factors. Repeat treatments may be performed as needed following clinical assessment.

Onset

Immediate visible improvement is usually achieved directly after injection, with final results becoming more apparent once initial swelling or redness subsides over the following days.

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