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Crystal Healer PN 2.5% (2.5 mL pre Filled syringe)

Crystal Healer PN 2.5% (2.5 mL pre Filled syringe)

Crystal Healer

Aesthetic injectable / skin booster
  • Manufactured by Koru Pharma, a registered aesthetics Pharma company, under regulatory standards applicable in South Korea and export markets.
  • Distributed through licensed aesthetic and mesotherapy product suppliers and intended for professional use only.
Polynucleotide (PN) skin-booster injection

Description

Crystal Healer PN 2.5% is a high-concentration polynucleotide (PN) skin-booster injectable designed to promote skin regeneration, collagen synthesis, improved elasticity and skin quality restoration. Supplied as a pre-filled 2.5 mL sterile syringe for professional aesthetic use, it aims at rejuvenating skin at the cellular level — reducing fine lines, improving texture, and supporting dermal extracellular matrix repair.

Bnefits

  • High concentration (2.5%) of purified polynucleotides (PN) for strong regenerative potential.
  • Stimulates fibroblast activity, collagen and elastin synthesis for improved skin elasticity, firmness and volume.
  • Supports extracellular matrix (ECM) renewal, enhancing dermal structural integrity and skin resilience.
  • Helps reduce fine lines, wrinkles and improves skin texture and density.
  • May improve skin hydration, barrier function and balance sebum production, leading to more even, healthier-looking skin.
  • Potential to improve post-acne scarring, stretch marks, enlarged pores and other signs of skin damage or aging.

Indications

  • Chronological and photo-ageing (fine lines, wrinkles, loss of elasticity, decreased skin density).
  • Loss of skin elasticity and firmness.
  • Post-acne or post-inflammatory dermal changes, scars and cicatricial skin damage.
  • Stretch marks, enlarged pores and uneven skin texture.
  • Skin areas with water imbalance (dehydrated skin) needing ECM support and hydration.
  • Patients desiring aesthetic rejuvenation, skin “bio-revitalisation”, improved glow, softness and overall skin quality improvement.

Composition

  • Sodium Polynucleotide (PN) — 25 mg/mL (2.5%) purified polynucleotides.
  • Phosphate-buffered saline (PBS) as solvent/carrier.
  • Lidocaine hydrochloride (as anaesthetic component to minimize injection discomfort).

Formulation

  • Sterile pre-filled syringe containing 2.5 mL PN solution (2.5% PN) for intradermal/subcutaneous injection as a skin booster.
  • Clear, low-viscosity injectable solution suitable for mesotherapy / skin-booster protocols.
  • Intended for professional use by qualified medical aesthetic practitioners.

Packaging

  • 1 box containing 1 sterile pre-filled syringe of 2.5 mL PN solution.
  • Syringe individually sealed and intended for single use only.
  • Packaging labelled with PN concentration, volume, lot/expiry details and usage instructions (for professionals).

Usage

  • Must be administered only by trained and certified medical aesthetic professionals.
  • Injection area should be cleansed and prepared under aseptic conditions prior to application.
  • Inject intradermally or subcutaneously into target skin areas (face, neck, décolleté, hands, other suitable regions) according to a mesotherapy / skin-booster protocol, dose and depth to be chosen by clinician based on individual skin condition.
  • Recommend a series of sessions: often 3–4 treatments spaced 3–4 weeks apart for optimal collagen and ECM stimulation, followed by maintenance treatments as advised by the practitioner.
  • Post-injection care: avoid excessive sun exposure, vigorous activity or skin irritation for recommended period; follow practitioner's guidance for aftercare. (Typical of PN/skin-booster treatments.)

Contraindications

  • Not for use in patients with known hypersensitivity or allergy to polynucleotides, lidocaine, or any component of the formulation.
  • Not recommended for use in individuals with active skin infections, dermatitis, open wounds, inflamed or compromised skin at the injection site.
  • Not suitable for patients with autoimmune disorders or certain systemic conditions unless cleared by a physician (common precaution for injectable skin boosters).
  • Use only in licensed medical settings by qualified professionals; not for self-injection or unqualified administration.

Adverse Effects

  • Transient injection-site reactions such as redness, swelling, mild bruising or tenderness.
  • Temporary mild discomfort or burning due to lidocaine; low but possible risk of allergic or hypersensitivity reactions to PN or other components.
  • Possible formation of small papules or unevenness if injection technique or depth is incorrect — underscores need for professional administration. (Common with mesotherapy/skin boosters.)
  • Risk of infection or other complications if aseptic technique is not properly maintained during injection and post-care.

Storage Conditions

  • Store unopened syringes in a cool, dry place, protected from direct sunlight and heat as per manufacturer instructions.
  • Preferably store refrigerated or under controlled room temperature depending on distributor’s guidance (check packaging).
  • Do not freeze. Use before the expiry date. Keep out of reach of children. Ensure sterility until point of use.

Duration

Not fixed; each session is a single injection visit. Visible skin-quality changes may accumulate over a series of sessions (e.g. 3\u20134 treatments over several weeks) with long-term maintenance as per practitioner\u2019s protocol.

Onset

Initial improvements in skin texture, hydration and glow may be noticeable within 2\u20134 weeks; collagen and elasticity improvements typically develop over several weeks to months after serial treatments.

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