Glutathione 600mg/4ml (TAD) Powder and Solvent for Injection and Infusion (10 Pack)
TAD Glutathione
Injectable antioxidant medicineGlutathione 600mg/4ml powder and solvent for solution for injection/infusion
Certifications
- Registered in various markets as a prescription medicinal product (e.g. as TAD 600 glutathione 600 mg lyophilised powder for IM/IV injection), classified as an antidote/other therapeutic agent.
- Manufactured under pharmaceutical Good Manufacturing Practice (GMP) and appropriate quality management systems for sterile parenteral preparations.
- Packaged and labelled in accordance with national medicines agency approvals (e.g. AIFA in Italy and other regulatory authorities where marketed).
- Registered in various markets as a prescription medicinal product (e.g. as TAD 600 glutathione 600 mg lyophilised powder for IM/IV injection), classified as an antidote/other therapeutic agent.
- Manufactured under pharmaceutical Good Manufacturing Practice (GMP) and appropriate quality management systems for sterile parenteral preparations.
- Packaged and labelled in accordance with national medicines agency approvals (e.g. AIFA in Italy and other regulatory authorities where marketed).
Glutathione 600mg/4ml powder and solvent for solution for injection/infusion
Description
Glutathione 600mg/4ml (TAD) Powder and Solvent for Injection and Infusion is a prescription-only pharmaceutical preparation containing lyophilised reduced glutathione with a matching solvent ampoule. Each vial of powder contains 646 mg of glutathione sodium salt, corresponding to 600 mg glutathione. When reconstituted with the accompanying 4 ml water for injections, it yields a 150 mg/ml solution for intravenous (IV) or intramuscular (IM) administration. TAD Glutathione is used in medical and wellness settings as a high-strength systemic antioxidant to support cellular protection, liver detoxification and oxidative stress reduction. The 10-pack presentation (10 powder vials + 10 solvent ampoules) is designed for professional use where reliable, therapeutic-grade glutathione supplementation is required.
Bnefits
- Provides a high-dose systemic source of glutathione, one of the body’s principal endogenous antioxidants.
- Helps neutralise free radicals and reduce oxidative stress at cellular level.
- Supports hepatic detoxification pathways and overall metabolic health.
- Injectable form ensures rapid systemic availability and high bioavailability when given IV or IM.
- Lyophilised powder plus solvent format allows precise, standardised reconstitution (150 mg/ml) for accurate dosing.
- Pharmaceutical-grade product manufactured to strict quality standards for stability, purity and predictable performance.
- Versatile administration options (slow IV injection or infusion, or IM injection) to fit different clinical protocols.
Indications
- Use as an antioxidant and detoxification-support therapy in conditions associated with increased oxidative stress, as determined by a prescribing clinician.
- Adjunctive treatment in clinical settings where enhancement of glutathione levels is considered beneficial for liver function and cellular protection.
- Use in medical and wellness practices for patients with depleted glutathione levels, toxin exposure or impaired endogenous antioxidant capacity, under medical supervision.
- Parenteral antioxidant support in patients who may not achieve adequate glutathione levels through oral supplementation due to poor absorption or metabolic issues.
Composition
- Active ingredient (per powder vial): 646 mg glutathione sodium salt, corresponding to 600 mg glutathione.
- Solvent ampoule: 4 ml water for injections.
- Reconstituted solution: 150 mg/ml glutathione in water for injections when the full 4 ml solvent is added to one powder vial.
- Other excipients: sterile formulation components in the lyophilised powder (as per official SmPC), present in small amounts to stabilise the product.
Formulation
- Lyophilised powder and solvent for solution for injection/infusion.
- Powder: white, freeze-dried glutathione contained in type III glass vials with rubber closure and aluminium seal.
- Solvent: 4 ml water for injections in type I glass ampoules, supplied as the dedicated diluent.
- After reconstitution, the solution is suitable for slow IV injection, IV infusion (after appropriate dilution) or IM injection, according to the prescribing doctor’s instructions.
- Prescription-only medicine; not a cosmetic product or food supplement.
Packaging
- Outer carton containing 10 powder vials and 10 solvent ampoules (4 ml each) per pack.
- Each powder vial: type III clear glass with rubber stopper and aluminium cap, holding lyophilised glutathione.
- Each solvent ampoule: type I clear glass ampoule containing 4 ml water for injections.
- Packaging clearly marked with product name, strength (600 mg/4 ml), pharmaceutical form (powder and solvent), batch number, expiry date, manufacturer and instructions for reconstitution and administration.
Usage
- For parenteral use only and only under the supervision of a qualified healthcare professional.
- Reconstitute immediately before use: aseptically draw the entire 4 ml of water for injections from the solvent ampoule into a sterile syringe with an appropriate needle.
- Remove the aluminium seal from the powder vial, disinfect the rubber stopper with an appropriate antiseptic swab, and inject the solvent into the vial, directing the flow towards the glass wall to minimise foaming.
- Gently swirl or rotate the vial until the lyophilised powder is completely dissolved; avoid vigorous shaking. The resulting solution contains 150 mg/ml glutathione.
- Visually inspect the reconstituted solution; use only if it is clear and free from visible particles or discoloration.
- Administer by slow intravenous injection, intravenous infusion (after further dilution in a suitable carrier solution, if required) or intramuscular injection according to the dosing regimen prescribed by the physician.
- Do not mix the reconstituted solution with other medicinal products in the same syringe or infusion bag unless compatibility has been specifically confirmed.
- Use the reconstituted solution within the stability period specified in official product information (commonly up to 8 hours at temperatures not exceeding 25°C); discard any unused portion safely.
- Dispose of used vials, ampoules, syringes and needles in approved sharps and pharmaceutical waste containers in accordance with local regulations.
Contraindications
- Known hypersensitivity to glutathione, glutathione sodium salt or any excipient in the formulation.
- Do not use if the vial, ampoule or reconstituted solution shows signs of damage, contamination, particulate matter or discoloration.
- Use in pregnancy or breastfeeding should generally be avoided unless the potential benefit clearly outweighs any potential risk and is specifically evaluated by a physician.
- Caution in patients with severe hepatic, renal or systemic conditions where parenteral fluid and antioxidant therapy may pose additional risk, unless clearly justified and monitored by a specialist.
Adverse Effects
- Local injection-site reactions such as pain, redness, induration or swelling at the IM or IV site.
- Occasional systemic symptoms including headache, nausea, dizziness or gastrointestinal discomfort in some patients.
- Allergic or hypersensitivity reactions (e.g. rash, pruritus, urticaria or, rarely, bronchospasm or anaphylactoid reactions) in susceptible individuals.
- As with any parenteral product, there is a risk of infection, phlebitis or thrombophlebitis if aseptic technique or venous access is inadequate.
- Electrolyte or metabolic changes are theoretically possible in the context of intensive antioxidant therapy and should be monitored in at-risk patients, according to clinical judgement.
Storage Conditions
- Store the unopened powder vials and solvent ampoules in the original outer carton to protect from light and physical damage.
- According to the SmPC, this medicinal product typically does not require any special storage conditions beyond normal room temperature; avoid extreme temperatures.
- Do not freeze; keep away from excessive heat and direct sunlight.
- Keep out of the sight and reach of children.
- Use only up to the expiry date printed on the packaging and vial/ampoule labels.
- After reconstitution, the solution should be used within the specified stability period (commonly up to 8 hours at a temperature not exceeding 25°C), after which any remaining solution must be discarded.
Duration
Treatment duration (single dose, short course or repeated cycles) is individualised and determined by the prescribing clinician based on indication, patient status and therapeutic response.
Onset
Systemic antioxidant action begins shortly after intravenous or intramuscular administration of the reconstituted solution; the observable clinical effect depends on the underlying condition, dose, and frequency of administration.
