ILLUMA Crystal Rose+ 5 x 5 ml
iLLUMA
Injectable Skin BoostersPolynucleotide (PN) injectable skin booster
Certifications
- Marketed as a professional Use injectable PN skin booster; no public evidence of MHRA licensed medicinal product status.
- Distributed in the UK/EU aesthetics sector under cosmetic/medical Aesthetic frameworks; any device or regulatory markings (e.g. CE/UKCA) are detailed in the official brochure and pack labelling rather than in open wholesale listings.
- Clinics are expected to use the product in accordance with local regulations governing injectable aesthetic treatments, patient consent and complication management.
- Marketed as a professional Use injectable PN skin booster; no public evidence of MHRA licensed medicinal product status.
- Distributed in the UK/EU aesthetics sector under cosmetic/medical Aesthetic frameworks; any device or regulatory markings (e.g. CE/UKCA) are detailed in the official brochure and pack labelling rather than in open wholesale listings.
- Clinics are expected to use the product in accordance with local regulations governing injectable aesthetic treatments, patient consent and complication management.
Polynucleotide (PN) injectable skin booster
Description
iLLUMA Crystal Rose+ 5 x 5 ml is an advanced polynucleotide (PN) skin booster formulated to rejuvenate dry, ageing and photo-damaged skin. The injectable PN filler works at a cellular level to enhance skin tone and texture, restore luminosity and improve elasticity in the face, neck and décolleté. Each 5 ml vial contains a highly concentrated cocktail of 53 active ingredients, including polynucleotides, hyaluronic acid (20 mg/ml), peptides and glutathione. This combination supports fibroblast activation, stimulates collagen and elastin synthesis, improves dermal regeneration and provides antioxidant protection against free radicals. Supplied as a box of five 5 ml vials, iLLUMA Crystal Rose+ is intended for use by trained medical and aesthetic professionals as part of structured biorevitalisation/PN skin booster treatment protocols.
Bnefits
- Deeply hydrates and rejuvenates dry, tired and dull skin by combining polynucleotides with hyaluronic acid (20 mg/ml).
- Improves overall skin tone, texture and elasticity, helping to soften fine lines and visible signs of ageing.
- Stimulates fibroblast activity and promotes new collagen and elastin production for firmer, more resilient skin.
- Supports cellular regeneration and long-term skin health via polynucleotides and a multi-active complex of 53 ingredients.
- Provides antioxidant protection and anti–free radical action through glutathione and other actives, helping to protect against environmental and oxidative stress.
- Works at the cellular level as a PN filler/skin booster to restore a more youthful glow to targeted areas such as the face, neck and décolleté.
- Highly concentrated bio-revitalisation ampoule suitable for combating age-related skin changes in professional treatment protocols.
- Flexible treatment course with an initial series for regeneration followed by maintenance sessions every few months to sustain results.
Indications
- Biorevitalisation of dry, dehydrated and ageing skin on the face, neck and décolleté.
- Improvement of uneven skin tone, dullness and loss of radiance associated with age or environmental damage.
- Enhancement of skin texture and elasticity where fine lines, superficial wrinkles and laxity have developed.
- Support of dermal regeneration and fibroblast function in patients showing early to moderate signs of photoageing.
- Adjunctive use with other professional aesthetic procedures (e.g. microneedling) where a PN skin booster is indicated, according to practitioner protocols.
- Professional use only in aesthetic and dermatology clinics by appropriately trained injectors.
Composition
- Polynucleotides (PN) – DNA-derived bio-revitalising fragments that support tissue repair, fibroblast activity and cellular regeneration.
- Hyaluronic acid 20 mg/ml – hydrating glycosaminoglycan to improve skin moisture, plumpness and elasticity.
- Glutathione – antioxidant tripeptide to help neutralise free radicals and support brightening and protection of the skin.
- Peptides – bioactive peptides selected to enhance collagen and elastin synthesis and support dermal matrix integrity.
- Total of 53 active ingredients (full INCI/ingredient list provided in the official iLLUMA Crystal Rose brochure/leaflet; detailed breakdown is not fully published by wholesalers).
Formulation
- Injectable, non-crosslinked PN skin booster / PN filler solution.
- Concentration: hyaluronic acid 20 mg/ml combined with polynucleotides, peptides, glutathione and additional active components.
- Sterile solution supplied in 5 ml glass vials for intradermal/mesotherapy-style administration by professionals.
- Polycomponent bio-revitalisation ampoule designed to act at cellular level to stimulate regeneration and collagen production.
Packaging
- Box containing 5 x 5 ml glass vials of iLLUMA Crystal Rose+.
- Each vial is individually sealed and labelled with product name, volume (5 ml) and batch information.
- Outer carton branded as iLLUMA Crystal Rose+ with indication that it is a polynucleotide (PN) skin booster, for professional use only.
- Some distributors also offer single 5 ml vials supplied individually outside of the full 5-vial box for clinic use.
Usage
- For professional use only; treatment should be carried out by suitably trained medical or aesthetic practitioners in accordance with local regulations.
- Assess the patient’s skin condition, medical history and contraindications before treatment; obtain informed consent and follow clinic protocols.
- Cleanse and disinfect the treatment area (face, neck and/or décolleté) according to aseptic technique.
- Administer iLLUMA Crystal Rose+ by appropriate injection technique (e.g. micro-papular/intradermal, nappage, mesotherapy-style injections or in combination with microneedling) as per the official protocol and practitioner training.
- Initial treatment course: perform the first 3 sessions every 2–3 weeks to enhance cellular regenerative capacity and build dermal improvements.
- Maintenance: after the initial course, perform additional top-up treatments every 3–6 months to maintain improved skin condition.
- Adjust injected volume and distribution according to treatment area, skin quality and individual patient needs, not exceeding recommended dose per session.
- After treatment, provide post-procedure care instructions (e.g. avoid makeup, saunas, sun exposure and vigorous exercise for a period as per clinic protocol; use high-SPF sun protection).
- Dispose of used vials, needles and syringes as clinical sharps waste in line with local regulations.
Contraindications
- Known hypersensitivity or allergy to any component of the formulation (e.g. hyaluronic acid, polynucleotides, peptides or glutathione).
- Active skin infections, inflammatory dermatoses or open wounds at the intended treatment site.
- History of severe keloid or hypertrophic scarring in the treatment area.
- Autoimmune diseases, uncontrolled systemic illness or immunosuppression where injectable biorevitalisation is contraindicated, according to clinician judgment.
- Pregnancy and breast-feeding, unless the practitioner determines otherwise in line with local guidance and available safety data (many aesthetic clinics list this as a precautionary contraindication).
- Known bleeding disorders or patients on anticoagulant therapy where there is a high risk of bruising/bleeding, unless carefully assessed by a medical professional.
- Any contraindications listed in the official iLLUMA Crystal Rose information leaflet or protocol documentation.
Adverse Effects
- Expected injection-related reactions such as redness, swelling, mild pain, tenderness, itching or bruising at the injection sites, typically resolving within a few days.
- Transient lumps or papules at injection points due to intradermal placement of the product, usually settling as the product disperses.
- Rare risk of local infection, abscess formation or delayed inflammatory reactions if aseptic technique is not strictly followed.
- Possible allergic or hypersensitivity reactions to one or more active substances or excipients.
- Very rare but potential vascular complications (e.g. occlusion) associated with injectable facial treatments, requiring prompt recognition and management according to emergency protocols.
- Post-inflammatory hyperpigmentation or temporary textural changes in susceptible individuals, particularly with aggressive needling or in darker skin types.
Storage Conditions
- Store in a cool, dry place at controlled room temperature as specified in the product leaflet (typically between 2°C and 25°C, avoiding extremes of temperature).
- Keep vials in their original outer carton to protect from light and contamination until use.
- Do not freeze; protect from excessive heat, direct sunlight and sudden temperature changes.
- Do not use after the expiry date printed on the packaging.
- Once a vial has been opened, use immediately and do not store partially used vials; discard any unused product safely according to clinic waste protocols.
Duration
Typical protocol recommends an initial series of 3 treatments spaced every 2\u20133 weeks, followed by maintenance sessions every 3\u20136 months; overall treatment duration is ongoing, depending on patient response and maintenance schedule.
Onset
Hydration and improved radiance may be noticed within days to a couple of weeks after treatment; collagen stimulation and more pronounced improvements in tone, texture and elasticity develop gradually over several weeks following the initial course.
| Price | Link |
|---|---|
| £100.00 GBP | https://www.twofaceaesthetics.com/products/illuma-crystal-rose |
| Price | Link |
|---|---|
| £18.00 | https://aesthipharma.co.uk/illuma-crystal-rose |













