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Intraline Two

Intraline Two

Intraline

Dermal Filler
  • CE certified hyaluronic acid dermal filler (Intraline Two listing on EU and UK Intraline sites)
  • Manufactured in Sweden in accordance with applicable medical device regulations
Hyaluronic Acid Filler

Description

Intraline Two is a biphasic, cross-linked hyaluronic acid dermal filler without lidocaine, designed for the correction of medium to deep wrinkles, lip enhancement, and facial contouring. The gel uses spherically shaped HA particles (20 mg/ml) to provide high viscosity, lifting capacity, and natural-looking volume restoration in areas such as nasolabial folds, marionette lines, perioral “smoker’s lines”, lips, chin, jawline, cheeks, and for non-surgical rhinoplasty.

Bnefits

  • Treats medium to deep wrinkles and folds, including nasolabial folds and marionette lines
  • Enhances and defines lips, including cupid’s bow, with high-definition results
  • Provides effective facial contouring for cheeks, chin, and jawline
  • Suitable for non-surgical rhinoplasty to refine nasal shape
  • Biphasic gel with spherical HA particles designed for smoother, natural results
  • High viscosity and large particle size for strong lifting and volumizing effects
  • Non-animal, highly purified HA with reduced risk of hypersensitivity
  • Long-lasting effect, typically up to 12 months depending on area and patient factors
  • Integrates well with tissue for natural feel and appearance
  • Supplied in prefilled syringe with sterile needles for precise professional use

Indications

  • Deep-set wrinkles and folds (e.g. nasolabial folds, marionette lines, perioral “smoker’s lines”)
  • Medium to deep facial wrinkles and lines
  • Lip enhancement, volume, and high-definition contour of cupid’s bow
  • Facial contouring in cheeks and jawline
  • Chin enhancement and reshaping
  • Non-surgical rhinoplasty (liquid nose reshaping)
  • General augmentation of facial tissues with volume loss

Composition

  • ingredient: Cross-linked sodium hyaluronate (Hyaluronic Acid)
  • concentration: 20 mg/ml

Formulation

  • Injectable, transparent viscoelastic biphasic hyaluronic acid gel
  • Large sphere size particles for deep-set wrinkle correction and contouring
  • Non-animal, bacterial fermentation-derived HA

Packaging

  • 1 x 1.0 ml prefilled glass syringe
  • 2 x 27G 1/2" Terumo needles
  • 2 traceability labels
  • Package insert
  • Sterile blister pack

Usage

  • For professional use only by appropriately trained and qualified medical practitioners.
  • Store and inspect the syringe and packaging to ensure sterility and that the product is within its expiry date before use.
  • Cleanse and disinfect the treatment area thoroughly; remove any makeup or skincare products.
  • Attach the supplied 27G needle securely to the prefilled syringe under aseptic conditions.
  • Inject slowly into the mid-dermis to lower dermis or upper subcutaneous layer, depending on the indication and treatment area.
  • Use appropriate injection techniques (e.g. linear threading, serial puncture, fanning) to achieve even distribution.
  • Do not exceed recommended volumes per area; typical maximum is 2 ml per treatment site per session as per professional guidelines.
  • After injection, gently massage the treated area to ensure uniform distribution of the gel and to smooth any irregularities.
  • Dispose of any unused product, used needles, and syringes as clinical biohazard waste according to local regulations.
  • Advise patients to avoid makeup on treated areas for at least 12 hours and to avoid extreme temperatures, saunas, and strenuous exercise for a few days post-treatment.

Contraindications

  • Known hypersensitivity or allergy to hyaluronic acid or any component of the formulation.
  • Presence of acute or chronic skin disease, infection, or inflammation (e.g. rashes, hives) at or near the planned injection site.
  • Pregnant or breastfeeding women.
  • Patients under 18 years of age.
  • History of severe allergies or anaphylactic reactions without appropriate specialist evaluation.
  • Injection into areas with permanent implants or concurrent aesthetic treatments (e.g. laser, radiofrequency) at the same site.
  • Active herpes simplex infection in the treatment area; patients with a history of cold sores should be managed according to professional protocols.
  • Patients with uncontrolled autoimmune or connective tissue disorders unless cleared by a specialist.

Adverse Effects

  • Transient pain or tenderness at the injection site
  • Redness (erythema) and swelling in the treated area
  • Bruising or haematoma formation
  • Itching or mild irritation
  • Firmness or nodules at the injection site
  • Discolouration at or near the treated area if injected too superficially
  • Rare but serious events such as vascular occlusion, tissue necrosis, or infection if incorrectly administered
  • Hypersensitivity reactions or granuloma formation (rare)

Storage Conditions

  • Store between 2°C and 25°C in a controlled environment.
  • Do not freeze the product.
  • Protect from direct sunlight and excessive heat.
  • Keep in original packaging until use to maintain sterility.
  • Do not use if packaging is damaged or if the solution appears cloudy or contains particulates.
  • Keep out of reach of children.

Duration

Single session with effects typically lasting up to 12 months; repeat treatments can be performed as required following professional evaluation.

Onset

Immediate visible improvement in volume and wrinkle correction after injection, with optimal results apparent once any initial swelling settles over several days.

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