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Jalupro (2 amps + 2 vials) Classic Amino Acid Biorevitaliser

Jalupro (2 amps + 2 vials) Classic Amino Acid Biorevitaliser

Jalupro

Aesthetic medicine
  • Class III medical device with CE marking under applicable European medical device legislation (e.g. Medical Devices Directive 93/42/EEC and subsequent MDR transition).
  • Manufactured under an ISO 13485–compliant medical device quality management system by Professional Derma SA.
  • Sterile, single Use injectable product intended exclusively for professional use in aesthetic medicine.
  • Conforms to relevant biocompatibility and safety standards for injectable dermal biorevitalisers.
Injectable skin booster / dermal biorevitaliser (mesotherapy)

Description

Jalupro (2 amps + 2 vials) – also known as Jalupro Classic – is a sterile, resorbable injectable mesotherapy solution that acts as a dermal biorevitaliser. It combines non-crosslinked hyaluronic acid in the form of sodium hyaluronate with a specific amino-acid complex (glycine, L-proline, L-leucine, L-lysine). By supplying fibroblasts with both hyaluronic acid and key amino acids, Jalupro stimulates fibroblast activity and collagen synthesis, improving skin texture, elasticity and hydration while reducing the appearance of fine lines, wrinkles, scars and stretch marks. The product can be used on the face and multiple body areas and is frequently employed as a complementary treatment alongside chemical peels, laser therapy, dermabrasion, radiofrequency, dermal fillers and botulinum toxin. Clinical effects build progressively and typically last up to about 6 months before maintenance is required.

Bnefits

  • Acts as a dermal biorevitaliser, stimulating fibroblasts and enhancing collagen production.
  • Improves overall skin texture and quality, giving a smoother, more refined appearance.
  • Reduces the appearance of fine lines, superficial wrinkles and early laxity.
  • Restores radiance and firmness to dull, photo-aged or devitalised skin.
  • Provides deep hydration via hyaluronic acid, helping the skin appear plumper and more elastic.
  • Improves the appearance of acne scars, red stretch marks and some keloid scars as part of a broader treatment protocol.
  • Helps prevent and reduce mild sagging of face and body skin.
  • Extends and enhances results of other aesthetic procedures (peels, laser, dermabrasion, radiofrequency, dermal fillers, botulinum toxin).
  • Multi-area indication: face, neck, décolleté, underarms, hands, inner thighs, abdomen and knees.
  • Provides long-lasting biorevitalisation, with results that can persist for up to around 6 months depending on skin type, age and lifestyle.

Indications

  • Improvement of skin texture and quality in light to moderately photo-aged or chrono-aged skin.
  • Fine lines and superficial wrinkles on the face, neck and décolleté.
  • Dull, devitalised or dehydrated skin lacking radiance and firmness.
  • Early skin laxity and loss of tone on the face and selected body areas.
  • Appearance of atrophic and acne scars, red stretch marks and keloid scars (as part of a combined treatment plan).
  • Bio-revitalisation and moisturising of face, neck, décolleté, hands, underarms, inner thighs, abdomen and knees.
  • Adjunctive treatment before and/or after physical or chemical procedures such as peels, laser therapy, dermabrasion, radiofrequency, dermal filler injections and botulinum toxin.
  • Supportive treatment for skin exposed to photo-ageing (e.g. sun damage) when used under professional guidance.

Composition

  • 2 sterile bottles containing lyophilised amino acids (each 100 mg total):
  • – Glycine
  • – L-Proline
  • – L-Leucine
  • – L-Lysine
  • 2 sterile vials containing sodium hyaluronate solution (each 30 mg in 3 ml):
  • – Sodium hyaluronate (non-crosslinked hyaluronic acid, non-animal origin)
  • – Water for injection
  • – Buffering and stabilising excipients as listed in the official product information

Formulation

  • Sterile, reabsorbable injectable solution for intradermal / mesodermal use.
  • Two-component system supplied as:
  • – Lyophilised amino-acid vials (A).
  • – Sodium hyaluronate ampoules or vials 30 mg/3 ml (B).
  • Immediately before use, the sodium hyaluronate solution is aseptically added to the amino-acid vial and gently mixed to obtain a clear, homogeneous injectable solution.
  • Once reconstituted, the solution functions as a dermal biorevitaliser, providing hyaluronic acid plus an amino-acid cluster to support fibroblast function and collagen synthesis.

Packaging

  • Standard pack configuration:
  • – 2 x sterile bottles containing 100 mg lyophilised amino acids (glycine, L-proline, L-leucine, L-lysine).
  • – 2 x sterile vials/ampoules containing 30 mg/3 ml sodium hyaluronate solution (to be mixed with the amino acids).
  • Supplied in a branded Jalupro outer carton with inner tray to secure vials and ampoules.
  • Includes package insert detailing composition, indications, preparation and administration instructions.
  • Each primary container carries batch number and expiry date.

Usage

  • Professional use only: Jalupro must be prepared and injected exclusively by suitably trained and qualified healthcare professionals in a clinical setting.
  • Reconstitute immediately before treatment by aseptically transferring the contents of one sodium hyaluronate vial (30 mg/3 ml) into one lyophilised amino-acid bottle (100 mg).
  • Swirl or roll gently until the powder is fully dissolved and a clear, homogeneous solution is obtained; avoid vigorous shaking that may create bubbles.
  • Draw the solution into a sterile syringe and attach an appropriate needle (commonly 30G or similar), according to the treatment area and technique.
  • Inject into the superficial to mid-dermis using micro-depot, nappage, linear threading or a grid technique, following the manufacturer’s recommendations and clinic protocol.
  • Treat indicated areas such as face, neck, décolleté, hands, underarms, inner thighs, abdomen and knees according to the planned protocol.
  • Typical initial regimens involve a course of several sessions (often 3–4, sometimes more) at intervals of roughly 10–20 days, tailored to patient age, skin condition and goals.
  • Jalupro may be used as a stand-alone biorevitalisation course or in combination with other aesthetic treatments (e.g. before or after peels, lasers, dermabrasion, radiofrequency, fillers, botulinum toxin) as clinically appropriate.
  • After injection, advise patients to avoid make-up on treated areas, strenuous exercise, saunas/steam rooms, alcohol excess and intense heat or sun exposure for at least 24 hours or per local protocol.
  • Do not store or reuse any reconstituted solution; discard any unused product. Dispose of vials, needles and syringes as clinical sharps waste according to local regulations.

Contraindications

  • Known hypersensitivity or allergy to hyaluronic acid, any of the amino acids (glycine, L-proline, L-leucine, L-lysine) or any excipient in the formulation.
  • Active skin infections, inflammatory dermatoses or open wounds at or near the intended injection sites (e.g. herpes simplex, bacterial or fungal infection, active dermatitis).
  • History of severe anaphylactic reactions to injectable aesthetic products unless thoroughly evaluated and deemed safe by a specialist.
  • Uncontrolled autoimmune disease or immunosuppression where intradermal biorevitalisation is considered inappropriate by the treating physician.
  • Known bleeding disorders or current significant anticoagulant/antiplatelet therapy without appropriate risk assessment and management.
  • Pregnancy and breastfeeding, due to lack of sufficient safety data (use is generally not recommended).
  • Recent aggressive procedures (deep chemical peels, ablative laser resurfacing, etc.) in the planned treatment area that have not fully healed or fall within a contraindicated window.
  • Use in patients unable to comply with post-procedure care instructions or in environments where adequate asepsis cannot be maintained.

Adverse Effects

  • Common transient injection-site reactions including redness (erythema), swelling (oedema), tenderness, itching and mild pain.
  • Small papules, bumps or nodules at injection points, typically resolving spontaneously as the product disperses over hours to days.
  • Bruising or ecchymosis, especially in vascular areas or in patients on anticoagulant or antiplatelet medications.
  • Temporary irregularities or mild asymmetry in treated areas that usually improve as swelling subsides.
  • Infrequent local infections or abscesses if aseptic technique is inadequate; these require appropriate medical treatment.
  • Rare hypersensitivity or allergic reactions, which may manifest with more marked swelling, erythema, pruritus or systemic symptoms and warrant immediate medical attention.
  • As with all injectable aesthetic procedures, very rare but serious complications such as vascular compromise or tissue necrosis are theoretically possible and must be managed promptly according to established aesthetic medicine guidelines.

Storage Conditions

  • Store in a cool, dry place at controlled room temperature within the range specified in the official product information (typically 2–25°C).
  • Do not freeze the product.
  • Keep vials and ampoules in their original outer carton to protect from light and contamination until the time of use.
  • Do not use after the expiry date printed on the packaging.
  • Reconstituted solution is intended for immediate use only and must not be stored or reused.
  • Store out of the reach and sight of children and unauthorised persons.

Duration

Initial treatment protocols typically consist of a course of 3\u20134 (and up to 4\u20136 in some protocols) sessions spaced approximately 10\u201320 days apart, depending on individual skin condition and practitioner preference. Clinical and aesthetic improvements usually persist for up to around 6 months, after which maintenance treatment (for example once or twice yearly or as clinically indicated) is recommended to sustain results.

Onset

Early improvements in hydration, radiance and skin softness may be noticeable within days to a few weeks after the first session, with progressive enhancement of texture, firmness and fine lines over the full course of treatment. Maximal visible benefit typically appears several weeks after completing the initial protocol and can persist for about 6 months, modulated by factors such as age, skin type, lifestyle and sun exposure.

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