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Jalupro Injectable Amino Acid Dermal Biorevitaliser

Jalupro Injectable Amino Acid Dermal Biorevitaliser

Jalupro

Aesthetic medicine
  • Class III medical device (dermal biorevitaliser) with CE marking under the applicable European medical device directives/regulations.
  • Manufactured by Professional Derma SA under an appropriate medical device quality management system (e.g. ISO 13485).
  • Sterile, single Use injectable solution intended exclusively for professional use in aesthetic medicine.
  • Pack includes full instructions for preparation and administration in line with medical device regulatory requirements.
Injectable skin booster / dermal biorevitaliser

Description

Jalupro is a sterile, reabsorbable injectable dermal biorevitaliser combining non-crosslinked hyaluronic acid with a specific amino acid complex (glycine, L-proline, L-lysine, L-leucine). It is designed to stimulate fibroblast activity and support new collagen and elastin synthesis, thereby improving skin quality, texture and elasticity. Jalupro helps to reduce the appearance of fine lines and wrinkles, restore volume in mildly atrophic or photo-damaged skin, and enhance hydration and radiance. It is indicated for the treatment of multiple areas including face, periorbital region (dark circles and under-eye bags), neck, décolletage, hands and other body sites affected by mild to moderate ageing, sun damage, dryness, loss of tone, stretch marks or acne scarring. Results typically last up to around 6 months, after which maintenance sessions are recommended.

Bnefits

  • Acts as a dermal biorevitaliser by stimulating fibroblasts and enhancing collagen and elastin synthesis.
  • Improves overall skin texture, elasticity and firmness with gradual, natural-looking results.
  • Reduces the appearance of fine lines, superficial wrinkles and early skin laxity.
  • Helps diminish dark circles and under-eye bags by improving dermal support and quality in the peri-orbital area.
  • Improves the appearance of photo-damaged skin, including sun-induced dryness and uneven texture.
  • Supports better skin hydration due to the presence of hyaluronic acid and its water-binding properties.
  • Can improve the appearance of acne scars, mild atrophic scars and stretch marks by promoting dermal remodelling.
  • Suitable for multiple treatment areas: face, neck, décolletage, hands and selected body sites.
  • Can be used as an adjunct before and/or after other aesthetic procedures (such as peels, laser, dermabrasion, radiofrequency and fillers) to enhance and prolong results.
  • Minimal downtime compared with more invasive procedures, with most patients resuming normal activities shortly after treatment.

Indications

  • Fine lines and superficial wrinkles of the face and neck.
  • Dark circles and mild bags under the eyes.
  • Photo-aged or sun-damaged skin with loss of tone and radiance.
  • General skin ageing with reduced elasticity and mild to moderate laxity.
  • Dry, dehydrated or dull skin lacking vitality.
  • Atrophic scars, including mild acne scarring and other superficial depressions.
  • Stretch marks (striae distensae).
  • Skin quality improvement on the neck, décolletage and hands.
  • Adjunctive treatment to support recovery and results following chemical peels, laser therapy, dermabrasion, radiofrequency and dermal filler procedures.

Composition

  • Sodium hyaluronate (hyaluronic acid) 30 mg in 3 ml (two ampoules, each 30 mg/3 ml).
  • Glycine 50 mg (per amino acid vial).
  • L-proline 37.6 mg (per amino acid vial).
  • L-lysine monohydrochloride 5.4 mg (per amino acid vial).
  • L-leucine 7 mg (per amino acid vial).
  • Water for injection 3 ml (in the hyaluronic acid ampoules).
  • Other excipients as listed in the official product information (buffering and stabilising agents).

Formulation

  • Sterile, reconstituted injectable solution acting as a dermal biorevitaliser.
  • Supplied as a two-component system: ampoules containing sodium hyaluronate solution and vials containing lyophilised amino acid powder.
  • Immediately before use, the hyaluronic acid solution is aseptically added to the amino acid vial and mixed until a clear solution is obtained for intradermal injection.
  • Non-crosslinked hyaluronic acid combined with a specific amino acid complex (glycine, L-proline, L-lysine, L-leucine) designed to provide fibroblasts with collagen-building substrates.

Packaging

  • Standard pack: 2 ampoules containing 30 mg/3 ml sodium hyaluronate solution.
  • 2 vials containing 100 mg lyophilised amino acids (glycine, L-proline, L-lysine, L-leucine).
  • Package insert with preparation instructions, indications and precautions.
  • Outer carton bearing the Jalupro branding, manufacturer details and regulatory markings (e.g. CE marking, device classification).

Usage

  • For professional use only; Jalupro must be administered by suitably trained and qualified healthcare professionals in an appropriate clinical setting.
  • Reconstitute immediately prior to use by transferring the contents of one sodium hyaluronate ampoule (30 mg/3 ml) into one amino acid vial (100 mg), using aseptic technique.
  • Gently swirl the vial until the lyophilised amino acids are completely dissolved and a clear, homogeneous solution is obtained; avoid vigorous shaking that may create bubbles.
  • Draw the solution into a sterile syringe; select needle gauge and injection technique according to the treatment area and clinical judgement (typically intradermal micro-deposits, nappage, linear threading or grid pattern).
  • Inject into the superficial to mid dermis of the chosen area (e.g. face, peri-orbital region, neck, décolletage, hands) following the manufacturer’s and clinic protocol.
  • Typical initial protocol for Jalupro Classic involves a course of several sessions (commonly 3–4 treatments) spaced approximately 7–10 days apart, adjusted to skin condition and indication.
  • After the initial course, maintenance sessions are usually recommended approximately every 6 months, or as clinically indicated, to sustain results.
  • Post-treatment, advise patients to avoid makeup, vigorous exercise, saunas/steam rooms and intense sun or heat exposure for at least 24 hours or as per clinic policy.
  • Counsel patients on the importance of daily broad-spectrum photoprotection and a supportive skincare routine to optimise and maintain outcomes.
  • Dispose of any unused solution, needles, syringes and vials according to local clinical sharps and biohazard waste regulations; do not store or reuse reconstituted product.

Contraindications

  • Known hypersensitivity or allergy to hyaluronic acid, any of the amino acids (glycine, L-proline, L-lysine, L-leucine) or any excipients in the formulation.
  • Active skin infections, inflammatory dermatoses or open wounds at or near the intended injection sites.
  • History of severe anaphylactic reactions or serious allergy to injectable aesthetic products, unless carefully evaluated and deemed safe by a specialist.
  • Autoimmune diseases or immunosuppression where intradermal biorevitalisation is considered inappropriate by the treating physician.
  • Known bleeding disorders or current use of significant anticoagulant/antiplatelet therapy without appropriate medical assessment.
  • Pregnancy and breastfeeding, due to limited clinical safety data in these populations (use is generally not recommended).
  • Concurrent or recent (within recommended intervals) aggressive procedures at the intended site (deep peels, ablative lasers, etc.) unless specifically cleared by the practitioner.

Adverse Effects

  • Typical injection-related reactions such as transient redness (erythema), swelling (oedema), tenderness, itching and mild pain at the injection sites.
  • Bruising or ecchymosis, especially in vascular areas like the periorbital region.
  • Temporary small papules or nodules at injection points, which usually resolve spontaneously as the product disperses.
  • Rarely, local infection or abscess formation if aseptic technique is not strictly followed.
  • Very rare hypersensitivity or allergic reactions, potentially presenting with widespread swelling, pruritus or other systemic symptoms.
  • As with other injectable procedures, very rare more serious complications (e.g. vascular compromise) are theoretically possible and require prompt recognition and management according to established aesthetic medicine guidelines.

Storage Conditions

  • Store in a cool, dry place at controlled room temperature as specified in the product leaflet (commonly between 2°C and 25°C); do not freeze.
  • Keep ampoules and vials in their original outer carton to protect from light and contamination until time of use.
  • Do not use after the expiry date printed on the packaging.
  • Reconstituted solution is intended for immediate use and must not be stored or reused.
  • Keep out of the reach and sight of children.

Duration

The initial treatment course typically consists of multiple sessions (often 3\u20134) performed at intervals of about 7\u201310 days, depending on the condition of the skin and the concerns treated. Clinical effects usually last up to around 6 months, after which a single maintenance treatment or a shorter course may be recommended, typically once or twice per year, according to individual response and practitioner assessment.

Onset

Some improvement in hydration and skin radiance may be visible within days to a few weeks after the first session, with progressive enhancement of texture, elasticity and fine lines over the full course of treatments as new collagen and extracellular matrix are laid down. Maximal visible results are generally observed several weeks after completing the initial protocol, with continued biorevitalising effects persisting for months before gradual decline.

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