Linerase Skin Regeneration Hydro (5x5ml Vials)
LINERASE
Biostimulator / MesotherapyNon-cross-linked hyaluronic acid skinbooster with amino acids
Certifications
- Class III CE Marked medical device for intradermal injection.
- Manufactured in accordance with applicable European medical device regulations and quality management standards (e.g. ISO 13485) as declared by the manufacturer.
- Class III CE Marked medical device for intradermal injection.
- Manufactured in accordance with applicable European medical device regulations and quality management standards (e.g. ISO 13485) as declared by the manufacturer.
Non-cross-linked hyaluronic acid skinbooster with amino acids
Description
Linerase Skin Regeneration Hydro (5x5ml Vials) is a professional low molecular weight, non-cross-linked hyaluronic acid (HA) mesotherapy solution enriched with a complex of amino acids. Designed as a filling and modelling solution for the dermal extracellular matrix, it provides immediate and long-lasting hydration while stimulating fibroblast activity and tissue regeneration. The combination of HA and amino acids supports collagen synthesis, improves skin elasticity and tone, and combats chrono- and photoageing. Following treatment, the skin appears more hydrated, supple, toned and radiant.
Bnefits
- Low molecular weight, non-cross-linked hyaluronic acid for deep hydration without volumising bulk.
- Amino acid complex supports fibroblast function and collagen synthesis, enhancing skin regeneration.
- Immediate hydrating, stimulating and toning effect typically noticeable within about 12 hours after treatment.
- Improves skin elasticity, density and overall skin quality on face and body.
- Helps prevent and treat early signs of skin ageing (fine lines, dullness, loss of tone).
- Brightens, nourishes and revitalises the skin for a more radiant complexion.
- Suitable for all skin types and for multiple facial and selected body areas.
- Medical device formulation intended for controlled intradermal or superficial subdermal injection.
Indications
- Biorevitalisation and hydration of the skin of the face, neck, décolleté and hands.
- Prevention and treatment of early and moderate signs of skin ageing (chrono- and photoageing).
- Improvement of skin elasticity, density and tone in atrophic or dehydrated skin.
- Supportive treatment for skin with reduced luminosity and uneven texture.
- Regeneration of the dermal extracellular matrix in areas such as cheekbones, nasolabial folds, corners of the mouth and chin.
- Adjunct to other aesthetic procedures where enhanced hydration and dermal matrix support are desired.
Composition
- Low molecular weight, non-cross-linked sodium hyaluronate (hyaluronic acid salt)
- L-alanine
- L-isoleucine
- L-leucine
- L-lysine
- L-proline
- L-valine
- Glycine
- L-serine
- Physiological buffer solution / excipients
Formulation
- Sterile, pyrogen-free, non-cross-linked hyaluronic acid solution with amino acids for intradermal injection.
- Low molecular weight HA for rapid distribution in the dermis and strong hydrating/biostimulating effect.
- Single-use vials intended to be used immediately after opening and discarded after the session.
Packaging
- Box containing 5 x 5 ml sterile glass vials of Linerase Skin Regeneration Hydro solution.
- Each vial is sealed and labelled for single-patient, single-session use.
Usage
- For professional use only by trained and qualified medical or aesthetic practitioners.
- Before treatment, perform clinical assessment, obtain informed consent and cleanse/disinfect the treatment area thoroughly.
- For each session, inject a total of 5 ml of Linerase Hydro into the treated area.
- Use an intradermal or very superficial subdermal technique, injecting approximately 0.1 ml per point in a grid pattern at roughly 2 cm intervals over the entire treatment area.
- Recommended needle size: 30G or 32G, with a length of about 4 mm (or equivalent mesotherapy needle).
- Common treatment areas include face (cheekbones, nasolabial folds, corners of the mouth, chin), neck, décolleté and hands, according to indication.
- Standard treatment protocol: one session every 7 days for 4 sessions, followed by 2 additional sessions every 15 days.
- Maintenance protocol: one session every month, or as clinically indicated based on patient response.
- Use strict aseptic technique; do not use if the vial is damaged, has been previously opened or if the solution appears cloudy or discoloured.
- Dispose of any unused product and sharps according to local regulations for medical waste.
- Provide post-treatment guidance including avoidance of make-up on treated areas for several hours, minimising sun/UV exposure and extreme temperatures, and using appropriate soothing or protective skincare products as recommended.
Contraindications
- Known hypersensitivity or allergy to hyaluronic acid, any of the listed amino acids or other components of the solution.
- History of severe allergic reactions or anaphylaxis.
- Active skin infection, inflammation or open wounds at or near the intended treatment sites.
- Autoimmune diseases or other systemic conditions where intradermal HA/biostimulator use is considered inappropriate by the treating physician.
- Pregnancy or breastfeeding (elective aesthetic injectable treatments are generally not recommended).
- Bleeding disorders or concurrent anticoagulant/antiplatelet therapy where increased bruising risk is deemed unacceptable.
- History of hypertrophic scarring or keloid formation, subject to practitioner judgment.
- Any serious systemic illness or dermatologic condition that, in the clinician’s opinion, makes treatment unsuitable.
Adverse Effects
- Transient erythema, swelling, tenderness or itching at the injection sites.
- Mild pain or discomfort during and shortly after injection.
- Small papules or wheals at injection points that typically resolve as the product disperses.
- Bruising or haematoma, particularly in patients prone to bruising or on anticoagulants.
- Rare delayed inflammatory reactions or local irritation.
- Very low but possible risk of infection if aseptic technique is not strictly followed.
Storage Conditions
- Store in original packaging in a cool, dry place at controlled room temperature as specified in the product leaflet (commonly between 2°C and 25°C).
- Protect from direct sunlight and heat sources.
- Do not freeze.
- Keep out of the reach and sight of children.
- Do not use after the expiry date or if vials or packaging are damaged.
Duration
Initial protocol typically consists of 4 weekly sessions (one every 7 days) followed by 2 sessions every 15 days, for a total of 6 sessions. Maintenance is usually one session per month thereafter, adjusted according to individual skin condition and clinical judgment.
Onset
Hydrating, stimulating and toning effects are generally noticeable within about 12 hours after treatment, with progressive improvement in skin texture, elasticity and radiance over the course of the treatment cycle.
