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Matrixyl 200mg (Topical)

Matrixyl 200mg (Topical)

Matrixyl

Peptides
  • Matrixyl (palmitoyl pentapeptide 4) is a cosmetic peptide active widely referenced in cosmetic science and dermatology literature but the Matrixyl 200mg (Topical) research product itself is not authorised as a medicinal product or medical device in the UK or EU.
  • Research peptide suppliers emphasise that Matrixyl 200mg (Topical) is sold for in vitro, laboratory or analytical use only and is not intended for human consumption, treatment or cosmetic application.
  • Derma Filler Ltd is registered as a private limited company in the UK (company number 13088463) with Companies House; its stated business activity includes retail sale via mail order houses or via internet.
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Topical cosmetic peptide (palmitoyl pentapeptide-4) for research and formulation

Description

Matrixyl 200mg (Topical) is a research-grade cosmetic peptide product supplied as 200 mg of lyophilized Matrixyl, scientifically known as palmitoyl pentapeptide-4 (also referred to as palmitoyl pentapeptide-3 in older literature). It is a lipopeptide composed of a palmitoyl (fatty acid) chain linked to the pentapeptide sequence Lys-Thr-Thr-Lys-Ser (Pal-KTTKS-OH). The product is provided as a topical-designated peptide in powder form that must be reconstituted before use. Matrixyl is widely investigated as a matrikine (messenger peptide) capable of signaling fibroblasts in laboratory models to increase extracellular matrix protein synthesis, including collagen, elastin and other dermal components. Research vendors describe this 200 mg topical format as a high-purity (>99%) peptide intended strictly for in vitro, ex vivo or other laboratory experimentation and for use in the development of topical formulations, not for direct use on humans or animals.

Bnefits

  • Contains Matrixyl (palmitoyl pentapeptide-4), a well-characterised cosmetic peptide investigated for its ability to stimulate collagen and other extracellular matrix proteins in laboratory models.
  • Supplied as a high-purity (>99%) lyophilized peptide, suitable for controlled research and formulation development work.
  • Topical-designated format (powder) that can be incorporated into experimental topical vehicles, creams or serums for in vitro or ex vivo testing of anti-ageing concepts.
  • Matrixyl is classified as a matrikine peptide, meaning it may act as a cell-signalling messenger in dermal fibroblast models, supporting studies on skin structure, firmness and elasticity.
  • In research settings, Matrixyl has been associated with increased collagen synthesis and improved dermal matrix markers, supporting its use as a model anti-wrinkle peptide in cosmetic science.
  • Lyophilized powder presentation in a sealed sterile vial improves peptide stability during shipping and storage prior to reconstitution.
  • Widely referenced in cosmetic dermatology literature as a benchmark peptide for studying anti-ageing and wound-healing pathways in skin.

Indications

  • Sold and described by research peptide suppliers as a cosmetic peptide for in vitro, ex vivo and other laboratory-based experimentation on skin-equivalent models, fibroblasts and related systems.
  • Intended for use in research on collagen synthesis, dermal extracellular matrix support, wrinkle formation and wound-healing processes in non-clinical settings.
  • May be used by formulation scientists as an active ingredient candidate when developing and testing experimental topical anti-ageing or skin-repair formulations in the lab.
  • Not indicated or approved as a medicinal product, cosmetic finished product or treatment for human or veterinary use in the form supplied.

Composition

  • Active ingredient: Matrixyl (palmitoyl pentapeptide-4, also known historically as palmitoyl pentapeptide-3).
  • Peptide sequence: Palmitoyl-Lys-Thr-Thr-Lys-Ser-OH (Pal-KTTKS-OH).
  • Peptide content: 200 mg per vial (as stated by multiple Matrixyl 200mg topical suppliers).
  • Molecular formula: C39H75N7O10.
  • Molecular weight: approximately 802.05 g/mol.
  • Purity: >99% (typical specification reported for Matrixyl 200mg topical by research peptide vendors).

Formulation

  • Dosage form: Lyophilized (freeze-dried) peptide powder in a sealed sterile vial.
  • Presentation: 200 mg Matrixyl (palmitoyl pentapeptide-4) per vial, labelled as topical cosmetic peptide.
  • Form state on receipt: Dry, off-white to white powder requiring reconstitution prior to experimental use.
  • Reconstitution: Vendors specify that the product "needs reconstitution before use"; the choice of solvent, diluent and final vehicle is determined by the research protocol and is not supplied with the vial.
  • Functional class: Lipopeptide / matrikine cosmetic peptide for research, often grouped within "cosmetic peptides" or "anti-ageing peptides" categories.
  • Typical research use: Incorporated into experimental topical formulations (e.g., serums, creams, gels) or used in solution to expose in vitro skin models or fibroblast cultures.

Packaging

  • Supplied as a single sterile, sealed vial containing 200 mg of lyophilized Matrixyl peptide.
  • Vial typically labelled with compound name, quantity (200 mg), and purity information as standard for research peptide products.
  • Shipped in protective outer packaging suitable for transporting temperature-sensitive research chemicals, according to supplier logistics.
  • No consumer-style outer carton or retail cosmetic packaging; supplied as a laboratory/research-grade reagent.

Usage

  • For qualified laboratory and research personnel only; not for human or animal use or consumption.
  • On receipt, inspect the vial intactness and labelling in accordance with institutional quality and safety procedures.
  • Reconstitute the lyophilized powder using a suitable sterile solvent or formulation vehicle appropriate to the intended in vitro or ex vivo experimental protocol, following general peptide-handling guidelines and any supplier-specific FAQ or technical documentation.
  • Use aseptic technique when opening and reconstituting the vial to avoid contamination of the peptide solution.
  • If preparing experimental topical formulations (e.g., creams, serums, gels) for in vitro or ex vivo testing, calculate the required peptide concentration based on the 200 mg content and the total batch size, and record all formulation details in the lab notebook or batch record.
  • Handle all solutions using appropriate personal protective equipment (PPE), including gloves, lab coat and eye protection, in accordance with institutional chemical safety policies.
  • Dispose of any unused peptide or solutions as laboratory chemical waste in compliance with local regulations and institutional guidelines.
  • Do not apply the product, reconstituted or otherwise, directly to human or animal skin, and do not inject or ingest under any circumstances.

Contraindications

  • Not for human therapeutic, cosmetic or veterinary use in the form supplied.
  • Contraindicated for injection, ingestion, direct application to human or animal skin or mucosa outside of ethically approved and legally compliant research protocols.
  • Should not be used by untrained individuals or outside of appropriately equipped laboratory or research environments.

Adverse Effects

  • No formal adverse effect profile exists for this research-grade Matrixyl 200mg (Topical) product, as it is not approved as a medicine or finished cosmetic product.
  • Potential risks include standard laboratory chemical hazards such as irritation or sensitisation on accidental contact, inhalation of dust or accidental exposure; appropriate PPE and lab safety procedures should be followed.
  • Any human or animal exposure would be outside labelled intent and could carry unknown risks; such use is prohibited by research peptide suppliers.

Storage Conditions

  • Follow the specific storage instructions provided by the supplying vendor or on the product label; for research peptides, this typically includes protecting the lyophilized powder from heat, moisture and light.
  • Keep the unopened lyophilized vial in a cool, dry environment; many laboratories store peptide vials refrigerated or frozen to help preserve stability until use.
  • After reconstitution, store solutions in appropriately labelled containers, under conditions (such as refrigeration) consistent with general peptide-handling practice and use them within a timeframe defined by internal stability assessments or supplier guidance.
  • Keep out of reach of unauthorised personnel and ensure storage is restricted to controlled laboratory environments.

Duration

Not applicable. Matrixyl 200mg (Topical) is supplied as a research peptide reagent and does not have an approved treatment regimen or recommended duration of use in humans.

Onset

Not applicable for clinical use. Any effects described in the literature (e.g., changes in collagen synthesis, wrinkle depth or wound healing) relate to controlled laboratory or clinical research contexts and not to approved therapeutic use of this specific research-grade product.

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