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Monalisa Dermal Filler Range (Soft, Mild, Hard, Ultra)

Monalisa Dermal Filler Range (Soft, Mild, Hard, Ultra)

Monalisa

Dermal Fillers
  • CE Marked medical device (Monalisa dermal fillers)
  • Manufactured under KGMP (Korean Good Manufacturing Practice)
  • ISO 13485 medical device quality management certified (manufacturer level)
  • ISO 9001 quality management system certified (manufacturer level)
Hyaluronic acid soft tissue filler

Description

Monalisa is a range of cross-linked hyaluronic acid dermal fillers developed by Genoss for the correction of fine to deep facial wrinkles, restoration of soft-tissue volume and contouring of facial features. The range includes Soft, Mild, Hard and Ultra formulations, each optimised for specific depths and indications around the mouth, lips, mid-face and other areas of volume loss. Monalisa fillers contain highly purified, non-animal hyaluronic acid with strong cross-linking chains and, in most products, 0.3% lidocaine to improve comfort during injection.

Bnefits

  • Restores soft-tissue volume and treats fine, medium and deep wrinkles depending on the formulation
  • Provides natural-looking, smooth and long-lasting aesthetic results
  • Based on highly purified, non-animal, cross-linked hyaluronic acid
  • Most products contain 0.3% lidocaine to reduce pain and discomfort during injections
  • High viscoelasticity and plasticity for precise contouring and shaping
  • Designed for stable gel structure with reduced risk of migration
  • CE-marked medical device with international quality certifications (e.g. KGMP, ISO 13485, ISO 9001)
  • Compatible with a wide range of treatment techniques and facial areas

Indications

  • Correction of fine, moderate and deep facial wrinkles and folds
  • Treatment of nasolabial folds and marionette lines
  • Lip augmentation, contouring and hydration
  • Perioral and vertical lip lines
  • Forehead wrinkles and glabellar (frown) lines
  • Periorbital lines (crow’s feet) and tear trough in appropriate indications
  • Chin, cheek and jawline volumisation and contouring (particularly with Hard and Ultra types)
  • Restoration of facial volume loss due to ageing

Composition

  • Cross-linked, non-animal hyaluronic acid (typically around 20–24 mg/mL depending on specific product)
  • Lidocaine hydrochloride 0.3% (in most Monalisa formulations with lidocaine)
  • BDDE (1,4-butanediol diglycidyl ether) as a cross-linking agent with very low residual level
  • Physiological phosphate buffer solution

Formulation

  • Sterile, pyrogen-free, viscoelastic, transparent and colourless hyaluronic acid gel
  • Pre-filled single-use glass syringe intended for injection into the dermis or subcutaneous tissue
  • Different viscoelastic profiles for Soft, Mild, Hard and Ultra to match indication and injection depth

Packaging

  • Typically supplied as 1 x 1.0 mL pre-filled single-use syringe (some variants 1.1 mL) per box
  • Each box generally includes 1 pre-filled syringe and 1–2 sterile single-use needles (commonly 25G, 27G and/or 30G depending on product)
  • Sterile blister packaging for syringe and needles
  • For professional use only

Usage

  • For administration only by appropriately trained healthcare professionals experienced in dermal filler injections
  • Select the appropriate Monalisa formulation (Soft, Mild, Hard or Ultra) according to treatment area, wrinkle depth and desired volumisation
  • Inject into the appropriate tissue plane as specified in the product instructions for use (e.g. superficial to mid-dermis for fine lines, mid- to deep dermis or subcutaneous/supraperiosteal for deeper folds and volumisation)
  • Use recommended needle sizes (commonly 25G–30G) and injection techniques such as linear threading, fanning, serial puncture or bolus, following manufacturer guidance
  • Aspirate carefully before injection to help avoid intravascular administration
  • Massage gently after injection if required to ensure even distribution of the gel
  • Do not inject into blood vessels, areas with active inflammation or infection, or regions with permanent fillers
  • Observe patients after treatment and provide post-procedure care advice (e.g. avoiding extreme temperatures, intense physical activity and manipulation of treated areas for a short period)

Contraindications

  • Hypersensitivity or allergy to hyaluronic acid, lidocaine or other amide-type local anaesthetics, or to any component of the product
  • History of severe allergic reactions or anaphylaxis
  • Active skin infection, inflammation or lesions at or near the intended injection site
  • Autoimmune diseases or uncontrolled systemic inflammatory conditions (according to physician judgement)
  • Tendency to develop hypertrophic scars or keloids
  • Pregnancy and breastfeeding (use not recommended)
  • Concurrent use in areas previously treated with permanent or semi-permanent fillers, unless expert assessment deems it appropriate
  • Known coagulation disorders or current anticoagulant/antiplatelet therapy that significantly increases bleeding risk (relative contraindication requiring risk–benefit assessment)

Adverse Effects

  • Transient erythema (redness), swelling and tenderness at the injection site
  • Pain or discomfort during and shortly after injection
  • Bruising or haematoma formation
  • Itching or local hypersensitivity reactions
  • Nodules, palpable lumps or unevenness in the treated area
  • Infection at the injection site if aseptic technique is not strictly followed
  • Tyndall effect (bluish discolouration) if injected too superficially
  • Rare but serious complications including vascular occlusion, tissue ischaemia and necrosis, or visual disturbances when inadvertently injected intravascularly

Storage Conditions

  • Store between 2°C and 25°C (do not freeze)
  • Keep in the original packaging and protect from light
  • Do not use if the packaging is damaged, if the syringe or needles have been previously opened, or after the expiry date
  • Store out of the reach of children

Duration

Typical aesthetic results last approximately 6\u201318 months depending on the specific Monalisa product used, treatment area, injection technique and individual patient factors.

Onset

Immediate visible effect after injection, with final result stabilising over the following days as any initial swelling subsides.

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