Nucleofill Eyes (Soft Plus 0.75%)
Nucleofill
Skin BoostersPolynucleotide Skin Booster (Periorbital / Eyes)
Certifications
- CE marked (manufacturer/distributor materials indicate CE conformity for Nucleofill range — verify certificate for specific SKU/batch).
- Marketed as a professional medical device/biostimulant for use by qualified practitioners.
- CE marked (manufacturer/distributor materials indicate CE conformity for Nucleofill range — verify certificate for specific SKU/batch).
- Marketed as a professional medical device/biostimulant for use by qualified practitioners.
Polynucleotide Skin Booster (Periorbital / Eyes)
Description
Nucleofill Eyes (formerly marketed as Nucleofill Soft Plus) is a sterile polynucleotide (sodium DNA) gel specifically formulated for periorbital rejuvenation. The product is supplied as a 2.0 mL prefilled syringe containing 15 mg polynucleotides (7.5 mg/mL). It is intended to improve dermo-epidermal skin quality, stimulate microcirculation and vascularity, support deep tissue regeneration and hydration, and reduce under-eye dark circles, fine lines and tear-trough hollows when administered by trained professionals.
Bnefits
- Improves periorbital skin quality and reduces fine wrinkles by stimulating fibroblasts and collagen production.
- Enhances microcirculation and vascularity—may reduce under-eye puffiness and dark circles over time.
- Supports deep tissue regeneration and redistribution of adipose tissue in hypotrophic areas.
- Provides long-lasting hydration of the extracellular matrix and improves skin texture.
- Formulated specifically for delicate eye area with low molecular-weight polynucleotides for tissue integration.
Indications
- Dark circles and periorbital hyperpigmentation
- Tear-trough hollows and under-eye hollowness (as a biostimulatory adjunct)
- Fine periorbital lines and micro-wrinkles
- Periorbital skin revitalisation and hydration
Composition
- Polynucleotide gel — 15 mg per 2.0 mL syringe (7.5 mg/mL)
- Purified polynucleotide fragments (reported molecular weight ~50–100 kDa for this variant)
- Sterile isotonic aqueous vehicle (full INCI/IFU available from manufacturer/distributor)
Formulation
- Sterile polynucleotide (sodium DNA) gel in a 2.0 mL prefilled syringe; pH reported between 6.8 and 7.2; viscosity reported ~28–35 Pa·s; non-crosslinked polynucleotide formulation intended for intradermal/subdermal injection in delicate areas.
Packaging
- 1 × 2.0 mL sterile prefilled syringe per box (many distributors include 2 × 30G × 13 mm needles in the pack — confirm contents with supplier).
Usage
- For professional use only — to be administered by trained healthcare practitioners experienced in periorbital injections.
- Inject intradermally or superficially into the periorbital/tear-trough area using microdroplet, linear or point injection techniques per IFU and clinician judgement.
- Typical course: multiple sessions (clinic protocols commonly 2–4 sessions spaced 2–4 weeks apart) depending on treatment goals.
- Observe aseptic technique and local aftercare guidance; avoid rubbing, heat exposure or strenuous exercise for 24–48 hours post-procedure.
Contraindications
- Active infection or inflammation at the intended injection site
- Known hypersensitivity to any component of the product
- Pregnancy and breastfeeding (use only after clinician risk–benefit assessment and per local guidance)
- Severe autoimmune disease or uncontrolled systemic illness (assess case-by-case)
Adverse Effects
- Common (usually transient): local erythema, swelling, bruising, tenderness, small papules or nodularity at injection sites.
- Less common/rare: infection, persistent nodules, hypersensitivity or allergic reactions.
- Technique-related complications (e.g., vascular compromise) are possible — appropriate technique and emergency measures should be available.
Storage Conditions
- Store in original packaging at room temperature as specified by manufacturer/distributor (avoid freezing and excessive heat).
- Protect from direct sunlight and keep out of reach of children.
- Check batch IFU for precise storage temperature and shelf-life/expiry information.
Duration
Progressive improvements commonly seen over weeks; longevity varies by patient and protocol \u2014 maintenance treatments typically recommended (clinic protocols vary).
Onset
Gradual \u2014 vascular and regenerative effects are often reported within ~30 days, with progressive improvement thereafter; immediate hydration/skin feel may be noticeable sooner.
| Price | Link |
|---|---|
| £46.99 | https://thecrystalpharmacy.co.uk/shop/product/?I=389 |
