Plinest Eye 2ml
Plinest
Injectable skin boosterPeriocular polynucleotide injectable gel
Certifications
- Class III CE Marked medical device (CE 0373) for intradermal use in the periocular area.
- Manufactured by Mastelli S.r.l. under a quality management system compliant with applicable medical device regulations (e.g. ISO 13485).
- Based on PN HPT® polynucleotide technology, supported by clinical data on safety and efficacy for improving periocular skin quality and texture.
- Class III CE Marked medical device (CE 0373) for intradermal use in the periocular area.
- Manufactured by Mastelli S.r.l. under a quality management system compliant with applicable medical device regulations (e.g. ISO 13485).
- Based on PN HPT® polynucleotide technology, supported by clinical data on safety and efficacy for improving periocular skin quality and texture.
Periocular polynucleotide injectable gel
Description
Plinest Eye is a PN-HPT® (Polynucleotides Highly Purified Technology) based injectable gel specifically designed for intradermal use in the periocular area and eye contour. Supplied as a 2 ml pre-filled syringe, it contains highly purified, fish-derived polynucleotides that stimulate fibroblasts, improve tissue regeneration and enhance skin quality. The treatment targets fine lines, dark circles, puffiness and loss of elasticity, helping to improve periocular skin texture, hydration and tone without adding unwanted volume.
Bnefits
- Formulated specifically for the delicate periocular area and eye contour.
- Contains highly purified polynucleotides (PN-HPT®) that stimulate fibroblasts and promote collagen and elastin production.
- Improves periocular skin texture, tone and elasticity while enhancing hydration.
- Helps reduce the appearance of fine lines, superficial wrinkles, dark circles and puffiness around the eyes.
- Provides a gentle, non-surgical rejuvenation option with minimal downtime.
- Non-volumising biostimulator focused on skin quality rather than bulk filling.
- Sterile, viscoelastic gel in a ready-to-use 2 ml pre-filled syringe for precise intradermal injections.
- Suitable for a wide range of skin types and ages when used by trained medical professionals.
Indications
- Improvement of periocular skin texture and quality.
- Treatment of fine lines and superficial wrinkles around the eyes.
- Reduction in the appearance of dark under-eye circles and mild puffiness.
- Restoration of elasticity and tonicity in thin, delicate skin of the eye contour.
- Periocular skin bioregeneration and hydration in patients with early signs of ageing.
Composition
- Highly purified polynucleotides (PN-HPT®) 7.5 mg/ml (15 mg total in 2 ml).
- Aqueous, sterile, non-pyrogenic gel carrier solution (exact excipients not fully specified in public technical data).
- Natural-origin DNA fragments derived from fish intended for human consumption, purified to remove proteins and other potentially immunogenic components.
Formulation
- Sterile, apyrogenic, viscoelastic polynucleotide gel for intradermal injection in the periocular area.
- Concentration: 7.5 mg/ml PN-HPT® in a 2 ml pre-filled syringe (total 15 mg polynucleotides).
- Class III CE-marked medical device intended for professional medical use only.
- Non-crosslinked, non-hyaluronic-acid, non-volumising biostimulatory injectable.
Packaging
- 1 x 2 ml pre-filled syringe of Plinest Eye polynucleotide gel per pack.
- 2 x 30G 1/2" sterile disposable needles included with each syringe.
- Single-use, sterile blister and carton packaging, labelled for professional use only.
Usage
- For use only by suitably trained and licensed healthcare professionals with experience in injectable aesthetic treatments.
- Cleanse and disinfect the treatment area according to standard aseptic protocols.
- Plinest Eye is injected intradermally in small amounts in the periocular area using microdroplet or linear retrograde techniques, as recommended in the official protocol.
- Typical treatment protocol consists of 3–4 sessions spaced 14–21 days apart, using 1–2 ml per session according to clinical judgement and patient needs.
- Inject into the superficial to mid-dermis around the eye contour, taking care to avoid intravascular injection and respecting anatomical danger zones.
- After injection, gentle massage of the treated area may be performed if appropriate to ensure even distribution of the product.
- Advise the patient on post-procedure care, including avoiding makeup on the treated area for several hours, limiting sun/heat exposure, and following clinic-specific aftercare instructions.
- Dispose of used syringe, needles and any remaining product immediately after the procedure in appropriate sharps and clinical waste containers; do not reuse or resterilise.
Contraindications
- Known hypersensitivity or allergy to fish-derived products, polynucleotides or any component of the formulation.
- Active skin infection, inflammation, dermatitis or other dermatological disease at or near the intended injection site.
- Severe systemic illnesses, uncontrolled autoimmune diseases or coagulation disorders in which injectable procedures are contraindicated unless the risk–benefit is carefully assessed.
- History of severe hypertrophic scarring or keloid formation in the periocular area.
- Pregnancy or breastfeeding, and patients under 18 years of age, due to insufficient safety data.
- Use by non-medical personnel or self-administration is contraindicated.
Adverse Effects
- Typical injection-related reactions include transient redness, swelling, bruising, tenderness or mild pain at the injection sites.
- Temporary papules or small lumps at injection points, generally resolving spontaneously over a few days.
- Occasional itching, warmth or mild discomfort in the treated area.
- As with other intradermal injectables, there is a risk of infection, prolonged inflammation, or rare granulomatous reactions, which may require medical management.
- Very rare but serious complications associated with intradermal injections, such as vascular compromise or tissue necrosis, may occur if product is inadvertently injected intravascularly or if improper technique is used.
Storage Conditions
- Store in a cool, dry place away from direct sunlight, within the temperature range specified on the packaging (typically controlled room temperature).
- Do not freeze and protect from excessive heat or sudden temperature changes.
- Keep the pre-filled syringe in its original carton until use to maintain sterility and protect from light and contamination.
- Do not use if the packaging, syringe or sterility seal is damaged, or after the expiry date printed on the pack.
Duration
A standard course usually comprises 3\u20134 treatment sessions at 14\u201321 day intervals. Clinical improvements generally persist for several months; many protocols recommend maintenance sessions every 6\u201312 months depending on patient age, skin condition and desired longevity of results.
Onset
Initial improvements in hydration and skin smoothness may be noticeable within days to a few weeks after the first sessions, with more pronounced gains in texture, elasticity and fine lines developing gradually over the course of 3\u20134 treatments and continuing to evolve over subsequent weeks as dermal regeneration progresses.
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