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RE: PRIMA i (1.1ml)

RE: PRIMA i (1.1ml)

RE:PRIMA

Injectable skin booster
  • No explicit public statements confirming CE marking or specific regulatory classification for RE: PRIMA i were identified in the distributor pages reviewed.
  • Clinics should check the physical packaging and documentation supplied with the product for device classification, CE mark and any local regulatory identifiers, and ensure compliance with UK/EU medical device and cosmetic regulations as applicable.
Under-eye polynucleotide tissue stimulator with Niacinamide

Description

RE: PRIMA i (1.1ml) is a next-generation injectable bio-revitalising skin booster specifically developed for the under-eye and periocular area. It combines medical-grade salmon DNA-derived polynucleotides (PN) at 2 mg/ml with Niacinamide (vitamin B3) at 2 mg/ml to provide anti-ageing, brightening, and regenerative effects. The product diminishes dark under-eye circles, improves fine lines and wrinkles, enhances skin elasticity and hydration, and supports tissue repair and cell regeneration. Effects are typically visible after the first treatment, with results lasting around 6–12 months when used in a short course of professionally administered sessions.

Bnefits

  • Anti-ageing and wrinkle reduction
  • Brightening of under-eye darkness and facial hyperpigmentation
  • Improvement of periocular fine lines and crow’s feet
  • Reduction of dark circles and eyebags
  • Improved skin elasticity and firmness
  • Enhanced skin hydration and texture
  • Cell and tissue regeneration with support of extracellular matrix
  • Skin rejuvenation and radiance enhancement
  • Support of natural collagen and elastin synthesis
  • Potential improvement of acne-prone skin and acne-related marks

Indications

  • Darkness under the eyes
  • Fine lines and wrinkles in the periocular area
  • Crow’s feet and periorbital wrinkles
  • Eyebags and tired under-eye appearance
  • Loss of elasticity and early sagging in the under-eye/upper dermis
  • Facial skin hyperpigmentation and dark spots
  • General skin dullness and uneven tone
  • Ageing, dehydrated or photo-damaged skin needing biorevitalisation

Composition

  • Polynucleotides (PN) 2 mg/ml – medical-grade, salmon DNA-derived polynucleotides
  • Niacinamide (Vitamin B3) 2 mg/ml
  • Aqueous injectable carrier solution (full excipient list not publicly disclosed; refer to official leaflet)

Formulation

  • Injectable polynucleotide-based skin booster solution for professional use
  • 1.1 ml pre-filled sterile syringe intended for periocular and facial intradermal/mesotherapy administration

Packaging

  • Retail carton containing 1 x 1.1 ml pre-filled syringe of RE: PRIMA i
  • Box and syringe labelled as under-eye skin booster combining Polynucleotides and Niacinamide
  • Supplied for professional medical/aesthetic use only; needles are selected separately according to clinic protocol

Usage

  • For professional use only; intended for doctors, nurses or cosmetologists trained in aesthetic injectable procedures.
  • Indicated primarily for the under-eye/periocular area but may also be used for selected facial regions according to professional judgment.
  • Typical treatment protocol described by distributors: 3 treatment sessions spaced approximately 4 weeks apart.
  • Recommended needle gauge (where stated): 31G to 33G fine needle for delicate periocular tissue.
  • Product is injected in small aliquots into the superficial to mid dermis of the indicated area as part of mesotherapy / skin booster protocols, following standard aseptic techniques.
  • Patients should be assessed for suitability, medical history and potential allergies prior to treatment.
  • Aftercare should follow the clinic’s standard protocol for injectable skin boosters (e.g., avoiding makeup and intense heat on the treated area for a short period, monitoring for local reactions).
  • Full, product-specific instructions, contraindications and safety information must be obtained from and followed as per the official package insert and manufacturer’s guidance.

Contraindications

  • Full, product-specific contraindications are not publicly detailed by distributors; users are instructed to consult the official package leaflet.
  • Distributors emphasise that the product is for professional use only and that purchasers must be qualified medical professionals or cosmetologists trained in aesthetic medicine.
  • Patients with known or suspected hypersensitivity/allergy to polynucleotides, Niacinamide or any excipient should not receive treatment.
  • Use should be avoided where injectable aesthetic procedures are generally contraindicated (e.g., active infection or inflammation at the injection site, severe systemic illness); refer to clinic protocols and official documentation.

Adverse Effects

  • Specific adverse effects for RE: PRIMA i are not listed in detail on public distributor pages.
  • As with other injectable skin boosters, typical temporary local reactions may include redness, swelling, bruising, tenderness or small papules at the injection sites.
  • Any serious, persistent or unexpected reactions should be managed according to standard medical practice and reported via appropriate pharmacovigilance channels.
  • Clinicians are advised to review the official package leaflet for the full safety profile and risk information before use.

Storage Conditions

  • Exact storage temperature range is not clearly specified in publicly available distributor information.
  • Standard practice for similar injectable skin boosters is storage in original packaging, protected from light and extremes of temperature, and not frozen.
  • Clinics should follow storage instructions printed on the RE: PRIMA i box and in the official package leaflet and comply with local medicines/device storage regulations.

Duration

Distributors report that results are visible after the first treatment and typically last approximately 6\u201312 months following a short protocol of around 3 sessions spaced 4 weeks apart (some sources describe durability as \u2018up to 9 months\u2019, reflecting individual variation).

Onset

Initial visible improvement is usually reported after the first treatment session, with immediate enhancement in skin hydration and radiance and progressive improvement in fine lines, dark circles and elasticity over subsequent weeks.

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