Logo
Rejuran HB Skin Booster (1 × 1 ml)

Rejuran HB Skin Booster (1 × 1 ml)

Rejuran

Skin booster
  • CE Marked PN and HA Based skin booster according to multiple EU/UK aesthetic distributors.
  • Manufactured in South Korea by PharmaResearch under medical device quality Management systems appropriate for injectable biostimulators.
  • Formulated in line with regional regulations governing injectable skin boosters and polynucleotide Based aesthetic products.
Polynucleotide (PN/PDRN) and hyaluronic acid injectable skin booster

Description

Rejuran HB Skin Booster (1 × 1 ml) is an advanced injectable skin booster that combines salmon-derived polynucleotides (PN/PDRN) with hyaluronic acid and a 0.3% numbing agent to regenerate, hydrate and soothe the skin. Designed to provide gentle, multi-layer hydration and dermal repair, it stimulates collagen and elastin production, enhances the extracellular matrix and improves barrier function. Suitable for the face, neck, décolleté and hands, Rejuran HB targets early signs of ageing, fine lines, UV-related damage, rough texture and dullness, delivering natural-looking rejuvenation with minimal downtime.

Bnefits

  • Provides deep, multi-layer hydration to restore skin moisture balance.
  • Stimulates collagen and elastin production, improving firmness and elasticity.
  • Promotes dermal repair and regeneration of UV-damaged and stressed skin.
  • Reduces the appearance of fine lines, superficial wrinkles and redness.
  • Improves overall skin texture, tone and radiance.
  • Enhances the skin barrier, increasing resilience to environmental stressors.
  • Can help smooth mild acne scars and textural irregularities as part of skin-quality improvement.
  • Contains a numbing agent (0.3%) to increase patient comfort during treatment.
  • Suitable for use on face (including under-eye, cheeks, nasolabial lines), neck, décolleté and hands.
  • Delivers subtle, natural rejuvenation with minimal downtime when performed by trained professionals.

Indications

  • Early signs of skin ageing such as fine lines and mild laxity.
  • Dehydrated, dull or tired-looking skin.
  • UV-damaged or environmentally stressed skin requiring repair.
  • Uneven skin texture and tone.
  • Redness and mild post-inflammatory changes.
  • Enlarged pores and mild textural imperfections.
  • Smoothing of mild acne scars and superficial depressions.
  • Skin quality improvement on face, neck, décolleté and hands.

Composition

  • Polynucleotides (PN / polydeoxyribonucleotide, PDRN) 1% derived from salmon DNA.
  • Hyaluronic acid (HA) 1%.
  • Numbing agent (local anaesthetic) 0.3% (commonly lidocaine hydrochloride).
  • Buffered aqueous solution (including sodium phosphate/disodium phosphate as buffering agents, exact formulation may vary by manufacturer disclosure).
  • Water for injections.

Formulation

  • Injectable, transparent PN and HA-based skin booster solution.
  • Combines salmon-derived polynucleotides with hyaluronic acid for dual regeneration and hydration.
  • Contains a 0.3% numbing agent for improved injection comfort.
  • Designed as a non-volumising hydro-booster rather than a traditional dermal filler.
  • Intended for micro-injection into superficial to mid-dermis for hydro-lifting and hydro-filling effects.
  • Sterile, pyrogen-controlled product supplied in a pre-filled syringe for single-patient use.

Packaging

  • 1 × 1 ml pre-filled sterile syringe per pack.
  • Recommended needle size: 33G (fine needle for superficial intradermal injections).
  • Syringe and needle typically supplied in sterile blister packaging.
  • Outer carton with product identification, batch number and expiry date.
  • Instructions for use (IFU) / product leaflet and, where applicable, traceability labels.

Usage

  • For professional use only: Rejuran HB must be administered by a licensed aesthetic practitioner or medical professional trained in injectable skin boosters.
  • Obtain detailed medical history and perform skin assessment to confirm indication and rule out contraindications; obtain informed consent prior to treatment.
  • Cleanse and disinfect treatment areas (face, neck, décolleté, hands) thoroughly with an appropriate antiseptic solution.
  • Inject Rejuran HB into the superficial to mid dermis using micro-injection techniques such as nappage, micro-papular, or serial micro-bolus patterns, spaced evenly across the treatment zone.
  • Recommended needle size is 33G; the practitioner may adjust needle length based on treatment area and depth.
  • Typical clinical protocols use a series of 3 treatment sessions spaced approximately 3–4 weeks apart for optimal results, with dosage per session tailored to skin condition and treated area.
  • Rejuran HB may be used alone or combined with other treatments (e.g. lasers, microneedling) as part of a comprehensive skin-rejuvenation plan, according to clinical judgment.
  • Inject slowly with low, controlled pressure; use correct depth and angle to avoid intravascular injection and unintended deep placement. Aspirate cautiously where appropriate.
  • Following injection, gentle massage may be applied to distribute the product evenly unless contraindicated.
  • Advise patients to avoid makeup on treated areas for several hours following treatment and to refrain from intense exercise, saunas, sunbeds, and extreme temperatures for at least 24 hours or per clinic protocol.
  • Practitioners should always follow the official instructions for use (IFU) and local regulatory guidelines for full details on dosing, technique, post-care, warnings and precautions.

Contraindications

  • Known hypersensitivity or allergy to polynucleotides, salmon-derived ingredients, hyaluronic acid, lidocaine (or other amide-type local anaesthetics) or any excipient in the formulation.
  • History of severe allergic reactions or anaphylaxis to injectable medical or cosmetic products.
  • Active skin infections, inflammatory lesions or dermatologic conditions (bacterial, viral such as herpes, or fungal) at or near the intended injection sites.
  • Autoimmune diseases or immunocompromised conditions unless, after careful evaluation, the treating physician determines that the benefits outweigh potential risks.
  • Uncontrolled systemic diseases or acute febrile illness.
  • Bleeding disorders, coagulation abnormalities, or concurrent use of anticoagulant or high-dose antiplatelet therapies that significantly increase bleeding risk, unless appropriately assessed and managed by a physician.
  • Pregnancy and breastfeeding (generally not recommended due to limited safety data).
  • Patients under 18 years of age.
  • Presence of permanent fillers or foreign bodies in the treatment area where there may be risk of interaction, unless evaluated and approved by an experienced practitioner.
  • Any general contraindication to injectable aesthetic procedures or local anaesthetics as determined by the treating healthcare professional.

Adverse Effects

  • Common, usually mild and transient injection-site reactions such as redness (erythema), slight swelling or oedema, tenderness, itching or a feeling of tightness.
  • Mild pain or discomfort at injection sites despite the presence of a numbing agent, typically resolving within hours to a few days.
  • Small papules or bumps at injection points (especially with micro-papular techniques), which usually subside over several days.
  • Minor bruising or haematoma at injection sites.
  • Temporary skin sensitivity or mild irritation in treated areas.
  • Occasional transient irregularities or asymmetry, which may require adjustment or additional treatment.
  • Rare delayed inflammatory or hypersensitivity reactions, including prolonged redness, swelling, induration or pruritus, requiring medical evaluation and management.
  • Infection at the injection site if aseptic technique is not strictly followed.
  • Very rare but serious complications associated with injectable treatments, such as inadvertent intravascular injection leading to tissue ischaemia or necrosis; such events require immediate emergency management by a suitably trained physician.
  • Any unexpected, persistent or severe adverse reaction should be promptly assessed and managed according to clinical best practice and the official product guidance.

Storage Conditions

  • Store according to the manufacturer’s recommendations, typically in a cool, dry place away from direct sunlight (often within 2–25 °C; check pack labelling).
  • Do not freeze.
  • Keep the syringe in its original packaging until use to protect from light and contamination.
  • Avoid exposure to excessive heat or sudden temperature changes.
  • Do not use after the expiry date printed on the packaging.
  • Use only if the packaging is intact and the solution appears clear and free from visible particles.
  • Single-use sterile product: do not resterilise and do not reuse any opened or partially used syringe.

Duration

After an initial course of approximately 3 sessions at 3\u20134 week intervals, results in hydration, texture and luminosity generally last around 6\u201312 months, depending on skin condition, lifestyle and adjunctive treatments. Maintenance sessions are typically recommended every 6\u201312 months to sustain and enhance outcomes.

Onset

Patients often notice improved hydration and radiance within days to a few weeks after the first treatment, while more pronounced improvements in fine lines, elasticity and overall texture develop progressively over 4\u20138 weeks and continue to build with subsequent sessions.

Browse more Skin booster

Top Treatments

Top Cities in the UK