REVS RMT 140HPn (3ml x 10 vials)
REVS
Skin BoosterPN and Hyaluronic Acid Mesotherapy Skin Booster for Anti-Aging and Skin Revitalisation
Certifications
- Manufactured by Reanzen Co., Ltd., a South Korean company listed as a manufacturer of cosmetic and aesthetic products with export certifications.
- Marketed by various European and UK distributors who state that their products are CE or CPNP registered where required, although specific CE device registration details for RMT 140HPn are not publicly disclosed.
- Intended and supplied exclusively for professional use in line with local regulations on injectable aesthetic and mesotherapy products.
- Formulated with non Crosslinked hyaluronic acid and polynucleotides in accordance with widely accepted safety and quality standards for injectable cosmeceutical skin boosters.
- Manufactured by Reanzen Co., Ltd., a South Korean company listed as a manufacturer of cosmetic and aesthetic products with export certifications.
- Marketed by various European and UK distributors who state that their products are CE or CPNP registered where required, although specific CE device registration details for RMT 140HPn are not publicly disclosed.
- Intended and supplied exclusively for professional use in line with local regulations on injectable aesthetic and mesotherapy products.
- Formulated with non Crosslinked hyaluronic acid and polynucleotides in accordance with widely accepted safety and quality standards for injectable cosmeceutical skin boosters.
PN and Hyaluronic Acid Mesotherapy Skin Booster for Anti-Aging and Skin Revitalisation
Description
REVS RMT 140HPn (3ml x 10 vials) is a professional-use PN and hyaluronic acid skin booster designed for mesotherapy-based skin rejuvenation. Developed by Reanzen Co., Ltd. in South Korea, this advanced cosmeceutical formulation combines non-crosslinked hyaluronic acid with polynucleotide (PN) extracted from salmon DNA and approximately 50 active ingredients, including amino acids, vitamins, minerals, co-enzymes, and antioxidants such as glutathione. The complex is engineered to optimise the skin’s regeneration environment by mimicking the amino acid ratio of collagen and the vitamin and mineral balance in blood, thereby supporting fibroblast activity, collagen synthesis, and skin turnover. RMT 140HPn targets multiple signs of aging, improving skin texture, tone, elasticity, moisture balance, pore appearance, and fine wrinkles. It is indicated for facial mesotherapy (particularly full-face rejuvenation) and can also be used on the neck, décolletage, and hands to restore radiance and firmness. Supplied as 3 ml vials in a box of 10, it is intended exclusively for trained medical and aesthetic professionals.
Bnefits
- Multi-tasking PN and HA skin booster that addresses texture, tone, elasticity, and hydration in a single treatment course.
- Restores moisture balance and delivers deep hydration through high-quality non-crosslinked hyaluronic acid.
- Polynucleotide (PN) component supports skin regeneration, fibroblast activity, collagen synthesis, and improved skin density.
- Helps refine and tighten pores, smooth skin surface, and improve overall skin texture.
- Improves skin tone and radiance, reducing dullness and contributing to a more even complexion.
- Assists in reducing fine lines and wrinkles, especially in photo-aged or lax skin.
- Approximately 50 active ingredients (amino acids, vitamins, minerals, co-enzymes, antioxidants) provide broad-spectrum nutritional support to skin cells.
- Designed to replenish elastic fibres lost due to ageing and to help restore the oil–water balance of the skin.
- Cosmeceutical formulation specifically created for professional dermatologists and aesthetic practitioners.
- Suitable as a stand-alone mesotherapy treatment or as part of a combined protocol with other aesthetic procedures such as dermal fillers and skin boosters.
Indications
- Mesotherapy-based facial rejuvenation and anti-aging treatment.
- Improvement of skin laxity, texture, and fine lines on the face.
- Enhancement of skin moisture balance and radiance in dehydrated or dull skin.
- Supportive treatment for enlarged pores and uneven skin texture.
- Skin tone improvement in cases of mild dyschromia and tired-looking skin.
- Rejuvenation of the neck and décolletage where skin shows early signs of ageing.
- Hand rejuvenation to improve hydration, texture, and fine lines when appropriate.
- Adjunct treatment in comprehensive anti-aging protocols alongside other injectables or aesthetic procedures.
Composition
- Non-crosslinked hyaluronic acid (HA) as a key hydrating and skin-conditioning agent (exact concentration not publicly disclosed).
- Polynucleotide (PN) derived from salmon DNA, designed to last longer than PDRN in the skin and to support regeneration and collagen remodelling.
- Approximately 50 active ingredients in total to support skin cell function.
- Amino acids formulated to mirror the amino acid ratio of collagen and provide building blocks for dermal matrix proteins.
- Vitamins to support cellular metabolism, antioxidant defence, and skin vitality.
- Minerals including calcium, potassium, sodium, and magnesium to help maintain physiological balance and cellular processes.
- Co-enzymes involved in key metabolic pathways relevant to skin repair and energy production.
- Antioxidant glutathione to help counteract oxidative stress and support skin brightening effects.
- Aqueous carrier solution suitable for injectable mesotherapy use (full excipient list not publicly disclosed).
Formulation
- Cosmeceutical PN and HA mesotherapy solution designed for intradermal / superficial dermal injection.
- Non-crosslinked, high-quality hyaluronic acid with strong water-binding capacity and skin affinity.
- Polynucleotide (PN) component formulated to promote regeneration, oil–water balance, and anti-wrinkle effects.
- Complex cocktail of roughly fifty bioactive ingredients (amino acids, vitamins, minerals, co-enzymes, antioxidant) at optimised ratios for collagen regeneration and fibroblast support.
- Sterile, pyrogen-free solution supplied in 3 ml glass vials for single-patient use per vial.
- Classified and marketed as a professional-use skin booster / mesotherapy product rather than a volumising dermal filler.
Packaging
- Standard presentation: box containing 10 x 3 ml sterile glass vials (total 30 ml of solution).
- Vials supplied in sterile packaging suitable for professional clinical environments.
- Outer carton labelled with product name (REVS RMT 140HPn), volume (3 ml x 10 vials), batch number, and expiry date.
- Typically offered by distributors in multiple purchasing configurations (e.g., single vial, 1 box of 10 vials, multi-box options).
- Intended for professional use only; each vial designed for one patient session or according to clinic protocol and local regulations.
Usage
- For professional use only: REVS RMT 140HPn must be administered exclusively by appropriately trained and qualified medical or aesthetic practitioners familiar with mesotherapy and facial anatomy.
- Before treatment, obtain a detailed medical history including allergies (especially to hyaluronic acid, fish/salmon-derived products, or any listed components), autoimmune conditions, bleeding disorders, current medications, and previous aesthetic procedures.
- Examine the treatment areas (face, neck, décolletage, hands) and determine suitability, treatment goals, and expectations; ensure informed consent is obtained.
- Inspect vials prior to use; do not use if the vial, seal, or packaging is damaged, if the solution is discoloured, or if particulate matter is visible, or if the product is past its expiry date.
- Maintain strict aseptic technique: disinfect practitioner hands, wear gloves, and thoroughly cleanse and disinfect the patient’s skin in the treatment area.
- Draw the required volume from the 3 ml vial into a sterile syringe using an appropriate needle; attach the recommended mesotherapy needle (commonly 30–32G, length and type per practitioner preference and protocol).
- Inject via mesotherapy techniques into the superficial to mid dermis according to local guidelines; methods may include micro-papular injections, point-by-point, nappage, or linear threading depending on indication and area.
- Avoid intravascular injection and take care around high-risk anatomical zones; inject slowly with minimal pressure and aspirate where clinically appropriate.
- According to manufacturer regimen guidance, the initial course typically consists of four treatment sessions at 15-day intervals, followed by two sessions at one-month intervals during the recovery phase.
- Once the maintenance phase begins, sessions are usually performed approximately once every 2–6 months, tailored to patient response, skin condition, and practitioner judgment.
- Do not mix REVS RMT 140HPn in the same syringe with other products unless specifically supported by compatible protocols and safety data.
- After treatment, gently massage treated areas only if needed to distribute product evenly; avoid excessive pressure that may cause bruising.
- Discard any unused remaining product in an opened vial at the end of the session; do not reuse opened vials on another patient. Dispose of needles and syringes in approved sharps containers.
- Provide post-procedure care instructions: avoid makeup on treated areas for around 12 hours, avoid intense heat exposure (saunas, hot baths, sunbeds) and strenuous exercise for 24–48 hours, and minimise alcohol intake immediately after treatment.
- Advise patients to avoid touching or massaging treated areas unnecessarily and to use broad-spectrum SPF daily to protect the skin.
- Instruct patients to contact the clinic promptly if they experience severe or increasing pain, significant or spreading redness, extensive bruising or swelling, signs of infection (warmth, pus, fever), or any other unexpected or concerning symptoms.
Contraindications
- Known hypersensitivity or allergy to hyaluronic acid, polynucleotides (including salmon-derived DNA), or any other component of the formulation.
- History of severe allergic reactions or anaphylaxis to injectable aesthetic or mesotherapy products.
- Active skin infection, inflammation, eczema, psoriasis, acne flare, or herpetic lesions at or near the intended injection sites.
- Tendency to form hypertrophic scars or keloids in the proposed treatment area.
- Pregnancy or breastfeeding (use is not recommended due to lack of safety data).
- Patients under 18 years of age.
- Uncontrolled systemic diseases, significant autoimmune disorders, or severe immunosuppression unless carefully assessed and approved by the treating physician.
- Severe coagulation disorders or current use of strong anticoagulant therapy, unless risk–benefit is carefully evaluated.
- Recent aggressive skin procedures (e.g., deep chemical peels, ablative laser resurfacing, dermabrasion) in the treatment area before complete healing has occurred.
- Injection into or very close to blood vessels or use in areas with significantly compromised vascularity or prior ischemic events.
Adverse Effects
- Common transient injection-site reactions such as redness (erythema), swelling (oedema), tenderness or pain, warmth, and mild bruising.
- Small papules or bumps at injection points, which usually resolve over several hours to days as the product disperses.
- Minor bleeding or hematoma at needle entry sites.
- Temporary changes in sensation (numbness, tingling, or heightened sensitivity) in treated areas due to needle trauma or local inflammatory response.
- Short-term pruritus (itching) or mild irritation around injection sites.
- Infrequent delayed inflammatory or hypersensitivity reactions presenting as prolonged redness, swelling, nodules, or induration that may require medical evaluation.
- Infection at injection sites, potentially leading to cellulitis or abscess formation if aseptic technique is not followed or aftercare is inadequate (rare).
- Formation of persistent nodules or granuloma-like reactions (rare), necessitating specialist assessment and possible specific treatment.
- Vascular events such as inadvertent intravascular injection or compression, which may cause pain, blanching, livedo, or, in severe cases, tissue ischemia and necrosis; though risk is lower with superficial mesotherapy techniques, it remains a serious potential complication requiring urgent management.
- Very rare but serious adverse events associated with injections in the facial region, such as visual disturbance or blindness in the event of embolisation, requiring immediate emergency intervention.
Storage Conditions
- Store at room temperature, typically between 1°C and 30°C, as indicated by distributor guidance; avoid extremes of temperature.
- Keep vials in their original packaging to protect from light, moisture, and contamination until use.
- Avoid direct sunlight and excessive humidity during storage.
- Do not freeze the product and do not use if it has been frozen or exposed to inappropriate storage conditions.
- Do not use after the expiry date printed on the vial and outer carton.
- Keep out of the sight and reach of children.
Duration
Clinical course is typically structured as four sessions at 15-day intervals followed by two sessions at one-month intervals, with maintenance treatments every 2\u20136 months; the visible benefits on hydration, texture, and tone generally persist for several months, depending on individual skin condition, lifestyle, and adherence to maintenance.
Onset
Hydration and radiance improvements are often noticeable shortly after treatment, with progressive enhancement of texture, tone, elasticity, and fine lines over subsequent weeks as dermal regeneration and collagen remodelling occur.
