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Richesse Eyes

Richesse Eyes

Richesse

Skin Booster
  • Manufactured in South Korea by JDBIO Co., Ltd., a specialist producer of medical aesthetic injectables and tissue stimulators.
  • Polynucleotide (PN) ingredient approved by the Korean Ministry of Food and Drug Safety (MFDS) for regenerative medical use in relevant contexts.
  • Distributed as a professional Use injectable tissue biostimulator; regulatory classification (cosmetic vs. medical device) may vary by country and should be confirmed locally before clinical use.
  • Intended only for use by qualified healthcare professionals in accordance with local laws and professional guidelines.
Polynucleotide (PN) tissue biostimulator for periorbital rejuvenation

Description

Richesse Eyes is a next-generation polynucleotide (PN) skin booster and tissue biostimulator specifically formulated for the delicate periorbital area. Using purified salmon-derived DNA (polynucleotides/PDRN), it induces intensive tissue regeneration, enhances the skin’s self-healing capacity and restores the structure of damaged or ageing skin from the epidermis through to the deep dermis. Designed for needle mesotherapy of the eye area and tear trough, Richesse Eyes provides a filling and revitalising effect without typical risks such as lumps or lymphatic stagnation. It effectively targets fine lines, wrinkles, dark circles and hollowness around the eyes, while also improving elasticity, firmness, brightness and overall skin quality. The PN-based formula strengthens the skin barrier, supports collagen and elastin synthesis and promotes a smoother, more radiant and youthful appearance in the eye area and other finely wrinkled regions such as the neck and hands.

Bnefits

  • Targets fine lines, wrinkles, dark circles and under-eye hollows for comprehensive periorbital rejuvenation.
  • Stimulates tissue regeneration and the skin’s natural healing processes from the epidermis to the deep dermis.
  • Strengthens the skin’s protective barrier, improving texture, resilience, elasticity and firmness.
  • Encourages new collagen and elastin synthesis for firmer, more youthful-looking skin.
  • Promotes natural radiance and skin brightening, improving tone and reducing dullness.
  • Provides a subtle filling effect in the tear trough area without causing lumps or lymphatic stagnation when correctly administered.
  • Improves fine lines on the face, neck and hands, making it suitable for broader anti-ageing protocols.
  • Derived from purified salmon DNA (PN/PDRN), offering high biocompatibility and regenerative potential.

Indications

  • Periorbital area including tear trough and under-eye hollows (fine lines, wrinkles, dark circles and volume loss).
  • Crow’s feet and lateral canthal fine lines.
  • Upper eyelids with mild laxity or creping (according to practitioner assessment and technique).
  • Fine lines and superficial wrinkles on the face, including perioral and cheek regions.
  • Neck lines and finely wrinkled skin in the neck area.
  • Dorsum of the hands where texture, fine lines and elasticity are compromised.
  • Patients seeking regenerative anti-ageing treatment rather than volumising filler alone in delicate areas.

Composition

  • Sodium Polynucleotide (PN) / Sodium DNA 1% (20 mg/mL) as the main active ingredient.
  • Polynucleotide derived from purified salmon DNA (PDRN origin) with low molecular weight for enhanced tissue repair.
  • Phosphate buffered saline (PBS), pH 7.0, as the carrier solution.
  • No lidocaine included in the formulation (analgesia to be provided separately if required).
  • Free of hyaluronic acid volumising gel; functions primarily as a polynucleotide tissue biostimulator.

Formulation

  • Injectable polynucleotide (PN) tissue biostimulator solution for mesotherapy-style use.
  • Concentration: Poly-nucleotide (PN) 1% (20 mg/mL) in phosphate buffered saline, pH 7.
  • Non-crosslinked, clear aqueous solution designed for superficial to mid-dermal deposition.
  • PN/PDRN derived from salmon DNA, refined to improve purity and regenerative efficacy.
  • Formulated for smooth injection with low viscosity suitable for micro-bolus and mesotherapy techniques.

Packaging

  • 1 pre-filled glass syringe of 1.0 mL Richesse Eyes solution per box.
  • Syringe supplied sterile and ready-to-use for professional injection.
  • Typically includes 2 x 30G (13 mm) needles in some kits (needle supply may vary by distributor).
  • Outer carton labelled with product name, active ingredient (PN/Sodium DNA), volume, batch number and expiry date.
  • Country of origin indicated as South Korea.

Usage

  • For professional use only by licensed medical or aesthetic practitioners trained in periorbital PN injection techniques.
  • Conduct a full medical history and assessment including skin condition, previous procedures, allergies (especially to fish-derived products or polynucleotides) and medications; obtain informed consent.
  • Cleanse and disinfect the treatment area thoroughly following clinic protocols for periocular injections.
  • Richesse Eyes is designed for needle mesotherapy of the eye area and tear trough; typical delivery involves multiple small micro-boluses or linear threading in the superficial to mid-dermis, avoiding intravascular injection and critical anatomical structures.
  • Recommended treatment protocol from manufacturer and distributors: a course of 3–4 sessions spaced approximately 2–3 weeks apart, adjusted according to individual response and practitioner judgement.
  • Initial improvements in softness and revitalisation are often reported within 3–5 days; further gains in elasticity and fine wrinkle reduction are typically observed over 2–4 weeks, with lifting and volume-enhancing effects becoming more apparent after 4–6 weeks.
  • Can be used primarily in the periorbital region (under-eye, crow’s feet) and, where appropriate, for fine lines on face, neck and hands using superficial mesotherapy-style injection patterns.
  • Avoid overfilling or injecting large boluses in delicate periocular tissues to minimise the risk of contour irregularities or swelling.
  • After treatment, advise patients to avoid touching or washing the treated area for at least 4 hours, and to avoid alcohol, seafood and very spicy food for 24 hours as per many protocol recommendations.
  • Recommend high-SPF broad-spectrum sun protection and gentle skincare post-procedure; avoid saunas, intense exercise and makeup on the treated area for the rest of the day or as per clinic protocol.
  • Dispose of any remaining product in an opened syringe at the end of the session; the product is single-use and must not be stored or reused.
  • All used needles, syringes and consumables must be disposed of in appropriate sharps and clinical waste containers.

Contraindications

  • Known hypersensitivity or allergy to polynucleotides, fish-derived ingredients (salmon DNA) or any other component of the product.
  • Active skin infections, inflammation, eczema, dermatitis or open wounds in the intended treatment area.
  • Severe or uncontrolled systemic diseases where regenerative injections may pose additional risk, unless cleared by an appropriate medical specialist.
  • History of severe allergic reactions or anaphylaxis to injectable cosmetic products.
  • Pregnancy or breastfeeding, due to limited safety data for PN/PDRN-based aesthetic treatments in these populations.
  • Known tendency to keloid or hypertrophic scarring in the proposed treatment region when using needle-based procedures.
  • Use in patients on strong anticoagulant or immunosuppressive therapy without careful risk–benefit assessment and appropriate precautions.

Adverse Effects

  • Expected transient injection-site reactions such as redness, mild swelling, tenderness or warmth around the treated area.
  • Pinpoint bleeding and minor bruising, particularly in the highly vascular periocular region.
  • Temporary oedema or puffiness under the eyes, usually resolving over several days.
  • Itching, tightness or mild discomfort at the injection sites in the early post-treatment period.
  • Rare local hypersensitivity or inflammatory reactions (prolonged redness, oedema, induration); treatment should be discontinued and appropriate medical steps taken if such reactions occur.
  • As with all injectable treatments, there is a theoretical risk of infection, vascular compromise or other procedure-related complications if improper technique or inadequate asepsis is used; emergency protocols should be in place in any treating clinic.

Storage Conditions

  • Store unopened product at a controlled temperature between 2°C and 8°C (refrigerated conditions).
  • Do not freeze; avoid temperature extremes and direct exposure to sunlight or heat sources.
  • Keep the syringe in its original blister and outer carton until use to maintain sterility and protect from light.
  • Do not use the product after the expiry date indicated on the packaging (typical shelf-life approximately 24 months from manufacture).
  • Once opened and used for a treatment session, discard any remaining product; do not attempt to resterilise or reuse.
  • Store out of the reach of children and non-professional users.

Duration

Clinical and distributor information suggests that aesthetic improvements can last approximately 6\u201312 months depending on patient factors, treatment protocol and aftercare; maintenance sessions are typically scheduled periodically to sustain results.

Onset

Subtle improvements in skin softness and radiance may be noticeable within 3\u20135 days after treatment, with progressive enhancement of elasticity, fine line reduction and periorbital contour over 2\u20136 weeks as tissue regeneration and collagen synthesis occur.

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