Azelaic 20% Cream (30g)
Skinoren
Topical dermatology medicationPrescription-only acne treatment (azelaic acid 20% cream)
Certifications
- UK MHRA Licensed medicinal product (Skinoren 20% Cream, PL 00043/0236).
- Manufactured under EU/UK Good Manufacturing Practice (GMP) for medicinal products.
- Distributed by Teleta Pharma, an MHRA Accredited, WDA Certified and GDP Compliant pharmaceutical wholesaler.
- UK MHRA Licensed medicinal product (Skinoren 20% Cream, PL 00043/0236).
- Manufactured under EU/UK Good Manufacturing Practice (GMP) for medicinal products.
- Distributed by Teleta Pharma, an MHRA Accredited, WDA Certified and GDP Compliant pharmaceutical wholesaler.
Prescription-only acne treatment (azelaic acid 20% cream)
Description
Azelaic 20% Cream (30g) is a prescription-only topical cream containing 20% w/w azelaic acid (marketed as Skinoren 20% Cream). It is used for the topical treatment of acne vulgaris, particularly mild to moderate acne affecting the face, chest or back. The cream has antibacterial, anti-inflammatory and comedolytic properties, helping to reduce Propionibacterium acnes, normalize keratinization, and decrease formation of comedones and inflammatory lesions.
Bnefits
- Topical treatment for mild to moderate acne vulgaris
- Reduces formation of comedones (blackheads and whiteheads)
- Antibacterial action against acne-causing bacteria (Propionibacterium acnes / Cutibacterium acnes)
- Anti-inflammatory effect, helping to reduce redness and swelling of acne lesions
- Helps to prevent new acne lesions while treating existing ones
- Well-established safety profile with low systemic absorption
- Alcohol-free cream base suitable for long-term use when tolerated
Indications
- Topical treatment of acne vulgaris in patients aged 12 years and older
- Mild to moderate acne on the face, chest and/or back, including inflammatory lesions and comedones
Composition
- Azelaic acid 20% w/w (200 mg azelaic acid per 1 g cream) – active ingredient
- Benzoic acid (E210) – preservative, may cause local irritation
- Cetearyl octanoate + isopropyl myristate (PCL Liquid)
- Glycerol 85%
- Propylene glycol – humectant, may cause local irritation
- Purified water
- Stearoyl macrogolglycerides
- Glycerol monostearate 40–55
- Cetostearyl alcohol – emulsifying agent, may cause local skin reactions (e.g. contact dermatitis)
Formulation
- Topical cream for cutaneous use
- White, opaque cream
- Strength: 20% w/w azelaic acid (200 mg/g)
- Pack size: 30 g aluminium tube
Packaging
- Aluminium tube with internal epoxide coating and polyethylene screw cap
- 30 g tube (other pack sizes such as 20 g and 50 g exist for the same brand, but Teleta supplies the 30 g pack)
- Outer carton with patient information leaflet
Usage
- For cutaneous use only.
- Apply Skinoren (Azelaic 20% Cream) to the affected areas of skin twice daily (morning and evening).
- As a guide, approximately 2.5 cm of cream (about 0.5 g) is sufficient for the entire facial area.
- If other areas (e.g. chest and back) also require treatment, adjust the amount of cream accordingly.
- Before application, thoroughly cleanse the skin with plain water and gently dry; a mild skin-cleansing agent may be used.
- Gently rub the cream into the affected areas.
- In patients with sensitive skin, use once daily (in the evening) during the first week of treatment, then increase to twice daily as tolerated.
- In the event of intolerable skin irritation, reduce the amount of cream applied or reduce the frequency to once daily until irritation subsides; if needed, treatment may be temporarily interrupted for a few days.
- Avoid contact with eyes, mouth and other mucous membranes; if accidental contact occurs, rinse with plenty of water.
- Wash hands after each application.
Contraindications
- Known hypersensitivity to azelaic acid.
- Hypersensitivity to any of the excipients (including benzoic acid, propylene glycol or cetostearyl alcohol).
Adverse Effects
- Very common: application site burning, application site pruritus (itching), application site erythema (redness).
- Common: application site exfoliation (peeling), pain, dryness, discolouration or irritation.
- Uncommon: application site paraesthesia (tingling), dermatitis, discomfort, oedema (swelling).
- Rare or frequency not known: application site vesicles or eczema, warmth, ulcer; urticaria; rash; cheilitis.
- Hypersensitivity reactions including angioedema, contact dermatitis, eye swelling, facial swelling.
- Worsening of asthma has been reported rarely in patients treated with azelaic acid.
- Local irritation usually decreases as treatment continues.
Storage Conditions
- Do not store above 30°C.
- Keep the tube tightly closed when not in use.
- Shelf life of unopened pack: typically 3 years (refer to pack expiry date).
- In-use shelf life after first opening: up to 6 months, provided storage conditions are followed.
- Keep out of the sight and reach of children.
Duration
Duration of use varies between patients and depends on acne severity. A distinct improvement is generally seen after about 4 weeks. For optimal results, continuous use over several months is recommended. Clinical experience supports continuous use for up to one year under medical supervision.
Onset
A noticeable improvement in acne is typically observed after approximately 4 weeks of regular twice-daily application.
| Price | Link |
|---|---|
| £6.73 | https://www.teleta.co.uk/product/azelaic-20-cream-30g |
