MG-EXO-SKIN by Dp Dermaceuticals is a professional-only Meso-Glide (MG) serum designed for use with the Dermapen 4 microneedling device. The ultra-regenerative formula combines exosomes derived from mesenchymal stem cells (MSC) with HylaFuse hyaluronic acid technology at 35 mg/ml and Calphasomes dual delivery systems. During microneedling, MG-EXO-SKIN helps the device glide smoothly over the skin while actively delivering performance ingredients to boost natural cellular repair, accelerate visible results and improve the appearance of multiple skin concerns, including sun damage, ageing, rosacea and pigmentation.
Bnefits
Stimulates natural cellular repair signals for younger-looking, more revitalised skin.
Regenerative exosomes accelerate microneedling outcomes and post-procedure recovery.
Helps improve the visible appearance of sun damage, fine lines, wrinkles and general signs of ageing.
Targets skin concerns such as rosacea, redness and blotchy or uneven skin tone.
Assists in reducing the appearance of pigmentation and post-inflammatory discolouration.
Contains HylaFuse hyaluronic acid at an unprecedented 35 mg/ml to deeply hydrate and plump the skin.
Calphasomes delivery technology enhances penetration and bioavailability of active ingredients.
Provides an optimal meso-glide texture so Dermapen 4 can move smoothly across the skin.
Supports barrier function and helps soothe stressed, post-treatment skin.
Formulated specifically for professional, in-clinic microneedling protocols as part of the MG-Collection.
Indications
Professional in-clinic use as a meso-glide serum during Dermapen 4 microneedling procedures.
Skin with visible signs of ageing, including fine lines, wrinkles and loss of firmness.
Photo-damaged skin with uneven tone, texture and dullness.
Rosacea-prone or redness-prone skin (where microneedling is deemed appropriate by the professional).
Hyperpigmentation and uneven pigmentation patterns, including sun spots and age spots.
Skin requiring enhanced regeneration and support after controlled micro-injury treatments.
Suitable for face, neck and other body areas treated with microneedling, according to professional protocols.
Composition
Exosomes derived from mesenchymal stem cells (MSC), harvested from Wharton’s Jelly.
HylaFuse Hyaluronic Acid at 35 mg/ml (multi-weight hyaluronic acid complex).
Calphasomes (phospholipid-based encapsulation and delivery system).
Vitamin C (Sodium Ascorbyl Phosphate).
Zinc PCA.
Pro-Vitamin B5 (Panthenol).
Aloe Vera.
Aqua and other cosmetic-grade excipients forming a professional meso-glide serum base.
Formulation
Professional-grade meso-glide serum formulated for use with automated microneedling devices (Dermapen 4).
High-concentration HylaFuse hyaluronic acid (35 mg/ml) for deep, multi-level hydration.
Exosome-enriched formula using MSC-derived exosomes as regenerative signalling vesicles.
Dual delivery mechanisms: HylaFuse for enhanced HA penetration and Calphasomes for targeted release of actives.
Non-injectable, topical serum designed to be worked into the skin via microneedling.
Free from typical everyday moisturiser textures; optimised for device glide and active delivery rather than general consumer use.
Packaging
Box containing 5 sterile 5 ml vials/ampoules of MG-EXO-SKIN serum (total 25 ml).
Each 5 ml vial is intended for professional, single-patient use according to clinic protocol.
Outer carton branded with Dp Dermaceuticals / DermapenWorld MG-Collection identity, product name and key technical details.
Professional-only labelling indicating use with Dermapen 4 and other MG-Collection products.
Usage
For professional in-clinic use only by trained and authorised practitioners familiar with Dermapen 4 microneedling protocols.
Use MG-EXO-SKIN as the dedicated meso-glide medium during Dermapen 4 treatments, applying to cleansed skin in accordance with the manufacturer’s protocol.
Dispense an appropriate amount of serum from the 5 ml vial onto the treatment area or into a sterile dish, replenishing as needed to maintain optimal glide.
Perform microneedling according to the selected protocol (needle depth, passes and pattern) while ensuring a continuous layer of MG-EXO-SKIN remains on the skin surface.
Follow with post-procedure care recommended by Dp Dermaceuticals (e.g. Hyla Active, cooling masks, SPF) and the clinic’s own aftercare guidelines.
Do not use for injection; MG-EXO-SKIN is strictly a topical meso-glide serum used in combination with microneedling.
Discard any unused product from an opened vial at the end of the treatment session in accordance with local clinic and infection-control policies.
Always refer to the official DermapenWorld / Dp Dermaceuticals instructions for use (IFU) and training materials for detailed treatment parameters and contraindications.
Contraindications
Use is contraindicated on compromised or infected skin where microneedling itself is contraindicated (e.g. active infection, open wounds, uncontrolled inflammatory dermatoses) according to professional judgement.
Known allergy or hypersensitivity to any component of the formula (e.g. hyaluronic acid, Aloe Vera, Vitamin C derivatives, Zinc PCA, Panthenol) or to exosome-based products.
Use should follow the same general contraindications and cautions that apply to Dermapen 4 microneedling, as defined in official training/IFU (e.g. certain systemic conditions, anticoagulant therapy, active skin cancers in the area, etc.).
Not intended for use by untrained persons or for at-home microneedling devices.
Avoid contact with eyes and mucous membranes; if contact occurs, rinse thoroughly with water and follow clinic protocol.
Adverse Effects
When used in conjunction with microneedling, transient erythema, mild oedema, warmth and tightness may occur as expected post-procedure responses.
Temporary dryness, flaking or sensitivity may be experienced during the short-term healing phases after treatment.
Rarely, hypersensitivity reactions such as persistent redness, itching or irritation may occur in individuals sensitive to one or more ingredients.
Any unusual, persistent or severe reaction following treatment should be assessed by the treating professional and managed according to clinical best practice.
Adverse events are more commonly associated with the microneedling procedure itself rather than with the serum; appropriate protocol adherence and aseptic technique are essential.
Storage Conditions
Store in a cool, dry place away from direct sunlight and excessive heat.
Keep vials in their original outer carton until use to protect from light and contamination.
Do not freeze.
Use within the expiry date printed on the packaging.
Once opened, use the contents of a vial for a single treatment session and discard any remainder in line with clinic protocol.
Duration
Used per microneedling session; overall course length (number and frequency of sessions) is determined by the treating professional based on skin condition, indication and clinic protocol.
Onset
Patients may notice increased hydration, radiance and smoother texture within days after treatment, with progressive improvements in tone, firmness and visible damage typically developing over several weeks to months as skin regeneration and remodelling occur.
