Marketed as a professional cosmetic / aesthetic exosome Based skin booster, not as a medicinal product.
Described by several European distributors as CE Marked for cosmetic use and imported from the European Community.
Plant Derived exosome origin is emphasised to minimise ethical concerns and align with vegan, non Animal product standards.
Marketed as a professional cosmetic / aesthetic exosome Based skin booster, not as a medicinal product.
Described by several European distributors as CE Marked for cosmetic use and imported from the European Community.
Plant Derived exosome origin is emphasised to minimise ethical concerns and align with vegan, non Animal product standards.
Manufacturing and distribution are claimed to comply with relevant cosmetic and medical device quality standards (e.g., ISO Based quality systems) in South Korea and the EU, though specific certificate numbers are not widely published.
Description
Exojuv is a professional, plant-derived exosome skin booster presented as a 2-vial system and supplied here as a pack of five complete sets. Developed by Oreon Life Science, Exojuv combines highly purified lyophilised plant exosomes from Centella Asiatica callus and other botanical cells with a bioactive amino acid complex containing polynucleotides, hyaluronic acid, amino acids, glutathione, vitamins and niacinamide. Each first vial contains around 5 billion plant-derived exosome particles, isolated and purified via a patented two-stage filtration process. When reconstituted with the second vial, the solution delivers a high density of growth factors, cytokines and signalling molecules to support anti-inflammatory action, cell proliferation, pigmentation reduction, antioxidant protection, wrinkle improvement and wound-healing support. The product is intended for topical professional application, often with mesotherapy or microneedling techniques, for advanced facial and body skin rejuvenation.
Bnefits
Delivers a high concentration of plant-derived exosomes (around 5 billion particles per vial) to support intensive skin regeneration.
Provides more than 250 types of growth factors and cytokines to enhance cellular communication and tissue repair.
Offers strong anti-inflammatory effects that help calm irritated and reactive skin.
Supports cell proliferation and dermal remodelling for improved texture and resilience.
Helps reduce pigmentation and uneven tone by modulating melanogenesis.
Provides powerful antioxidant protection via glutathione, vitamins and plant-derived factors, protecting skin from oxidative stress.
Improves fine lines and wrinkles by increasing type I procollagen and supporting collagen synthesis.
Enhances wound-healing responses and post-procedure recovery when used after aesthetic treatments on intact skin.
Hydrates and plumps the skin through hyaluronic acid and amino acids in the activator solution.
Plant-derived exosomes are biocompatible and designed to minimise immune or inflammatory reactions compared with many synthetic nanomaterials.
Indications
Facial and body skin rejuvenation in aesthetic and dermatological practice.
Manufacturing and distribution are claimed to comply with relevant cosmetic and medical device quality standards (e.g., ISO Based quality systems) in South Korea and the EU, though specific certificate numbers are not widely published.
Practitioners should verify local regulatory status and guidance for exosome Based products before clinical use, as this area is evolving.
Practitioners should verify local regulatory status and guidance for exosome Based products before clinical use, as this area is evolving.
• Tea Tree Exosome – purifying, protective exosomes with antimicrobial support.
• Cica Exosome (Centella/‘cica’ complex) – regeneration-supporting and calming exosomes.
• Collagen – supports firmness, elasticity and extracellular matrix structure.
• Growth factors and cytokines (around 250 types) encapsulated within exosomes.
Vial 2 – Amino Acid Complex (5 ml activator solution):
• Polynucleotides (PN / polynucleotide complex) – support DNA repair, cell renewal and tissue regeneration.
• Hyaluronic Acid – hydrating polymer that improves moisture retention and skin plumpness.
• Amino Acids – building blocks for protein synthesis, collagen formation and repair mechanisms.
• Glutathione – antioxidant and brightening tripeptide that helps neutralise free radicals and reduce pigmentation.
• Vitamins – supportive micronutrients for antioxidant defence and cellular metabolism.
• Niacinamide (reported by some distributors) – barrier-supporting, brightening and anti-inflammatory B3 derivative.
• Aqueous excipient system suitable for topical and mesotherapeutic use (full INCI not publicly disclosed).
Formulation
Professional exosome-based skin booster.
Two-vial set consisting of lyophilised exosome powder and a liquid amino acid activator.
Plant-derived, high-purity exosomes obtained from Centella Asiatica and additional botanical cell cultures via a patented two-stage filtration and isolation process.
Non-human, non-animal, non-bacterial exosome source designed to minimise ethical and regulatory concerns surrounding human stem-cell products.
Formulated for topical professional use, often combined with microneedling, mesotherapy or other transdermal delivery techniques.
Cosmetic / aesthetic regenerative product, not a dermal filler or traditional injectable volumiser.
Packaging
Pack of 5 complete Exojuv sets.
Each individual set contains:
• 1 x Vial 1: plant-derived lyophilised powder (exosome complex; around 5 billion particles / 50 mg class).
• 1 x Vial 2: 5 ml amino acid activator complex.
Total pack contents:
• 5 x Vial 1 – Plant Derived Lyophilised Powder.
• 5 x Vial 2 – 5 ml Amino Acid Complex.
Supplied in professional packaging branded Exojuv, with storage and handling instructions for clinic use.
Usage
For professional use only by appropriately trained and licensed practitioners, according to local regulations.
1. Prepare the treatment area:
• Cleanse the skin thoroughly.
• Apply topical anaesthetic to the treatment area if using mesotherapy or microneedling; remove once adequate anaesthesia is achieved and cleanse again.
2. Reconstitution:
• Open Vial 2 (amino acid complex) and Vial 1 (lyophilised powder) as directed.
• Pour the full contents of Vial 1 into Vial 2 (or vice versa as per local protocol) to combine the lyophilised powder with the activator solution.
• Shake gently but thoroughly and allow 3–5 minutes for complete dissolution of the powder.
3. Application:
• Apply the reconstituted solution topically to the treatment area, either:
– Directly on the skin and then perform microneedling or other transdermal delivery procedures to enhance penetration, or
– Via mesotherapy or similar microinjection technique according to clinic protocol and local regulations.
• Distribute the solution evenly across the target area (face, neck, décolletage, scalp or body), avoiding intravascular injection and respecting depth guidelines.
4. Post-treatment:
• Gently remove excess product if required and apply soothing, non-occlusive post-procedure skincare.
• Advise the patient on post-care, including sun protection and avoidance of irritants.
5. Handling:
• Use the full reconstituted mixture for a single session; discard any unused portion unless the manufacturer’s documentation clearly supports storage and reuse.
• Maintain aseptic technique during reconstitution and application to minimise infection risk.
Contraindications
Known hypersensitivity or allergy to any component of Exojuv, including plant-derived exosomes (Centella Asiatica, lavender, tea tree, cica), collagen, polynucleotides, hyaluronic acid, amino acids, glutathione, vitamins or excipients.
Active skin infections (bacterial, viral or fungal) at the intended treatment area.
Severe inflammatory skin disease or uncontrolled dermatoses (e.g., severe eczema, psoriasis flare, severe rosacea, severe acne) at the treatment site without specialist oversight.
Open wounds, ulcerations or non-re-epithelialised areas in the treatment field.
History of severe anaphylactic reactions to injectable or mesotherapy products in the same class.
Severe systemic illness or immunosuppression where wound healing may be compromised, unless carefully evaluated and cleared by a supervising physician.
Pregnancy and breastfeeding: although plant-derived exosomes are promoted as not crossing the placenta in marketing materials, robust clinical safety data are limited; use should be avoided or only considered after medical risk–benefit assessment.
Use by unqualified individuals or outside appropriate clinical settings and protocols.
Adverse Effects
Transient erythema, swelling and warmth at the treatment site, especially when used with microneedling or mesotherapy.
Mild discomfort, tenderness or bruising in treated areas.
Temporary dryness, tightness or flaking as skin regenerates.
Exacerbation of underlying inflammatory skin conditions in susceptible individuals if not properly assessed.
Rare allergic or hypersensitivity reactions manifesting as persistent redness, itchiness, burning, rash or swelling.
Very rare risk of infection, scarring or post-inflammatory hyperpigmentation, particularly if aseptic technique is not followed or aggressive procedures are combined inappropriately.
Any unusual, severe or prolonged adverse effect should prompt immediate cessation of treatment and medical evaluation.
Storage Conditions
Store in a cool, dry place away from direct sunlight and excessive heat, as specified on the product packaging.
Keep vials in their original packaging until use to protect from light and environmental contamination.
Do not freeze unless expressly permitted by the manufacturer.
Use before the expiry date printed on each vial and outer box.
Once reconstituted, use promptly and do not store for extended periods unless supported by official instructions.
Keep out of reach of children and unauthorised personnel.
Duration
Typical protocols recommend one Exojuv session every 1\u20132 weeks for an initial course of 4\u20136 sessions, followed by maintenance treatments every 3\u20136 months as needed. Exact treatment schedule, number of sessions and maintenance frequency should be determined by the treating practitioner based on indication, skin condition and patient response.
Onset
Early improvements in hydration, glow and skin comfort may be noticed within days after the first treatment, whereas more pronounced benefits such as reduced inflammation, smoother texture, decreased pigmentation and improved fine lines typically develop progressively over several weeks and a full course of sessions. Longevity of results varies by indication, technique and patient factors.
