PROFHILO STRUCTURA IBSA (1 x 2 ml)

Profhilo

Injectable aesthetic medical device

Hyaluronic acid lipolifting bioremodeling injectable for adipose tissue restoration

CE Marked Class III injectable hyaluronic acid medical device for intradermal/subcutaneous use in facial adipose tissue restoration and lipolifting.
Manufactured using IBSA’s NAHYCO Hybrid Technology to produce stabilised hybrid cooperative complexes of high and low Molecular Weight hyaluronic acid without chemical cross Linking agents such as BDDE.
Produced under IBSA Group’s pharmaceutical and medical device quality systems in compliance with applicable EU Medical Device Regulation and relevant ISO/EN standards for sterile injectable devices.

CE Marked Class III injectable hyaluronic acid medical device for intradermal/subcutaneous use in facial adipose tissue restoration and lipolifting.
Manufactured using IBSA’s NAHYCO Hybrid Technology to produce stabilised hybrid cooperative complexes of high and low Molecular Weight hyaluronic acid without chemical cross Linking agents such as BDDE.
Produced under IBSA Group’s pharmaceutical and medical device quality systems in compliance with applicable EU Medical Device Regulation and relevant ISO/EN standards for sterile injectable devices.

Hyaluronic acid lipolifting bioremodeling injectable for adipose tissue restoration

Description

PROFHILO STRUCTURA IBSA (1 x 2 ml) is a Class III CE-marked injectable hyaluronic acid medical device from IBSA Derma specifically developed for lipolifting and deep structural rejuvenation of the face. Each pre-filled 2 ml syringe contains 90 mg of ultrapure hyaluronic acid in the form of hybrid cooperative complexes (HCC) of high- and low-molecular-weight HA (45 mg H-HA + 45 mg L-HA), created using IBSA’s patented NAHYCO thermal technology. PROFHILO STRUCTURA is indicated for facial treatment with the specific intended use of restoring adipose tissue and improving deep laxity, targeting age-related fat atrophy and contour changes. Injected into superficial subcutaneous fat compartments with cannula-based techniques, it provides deep hydration, structural support and regeneration of facial fat tissue, improving firmness, elasticity, contour definition and overall skin texture while stimulating collagen and elastin production. The formulation is thermally stabilised, free from BDDE and other chemical cross-linking agents, and designed for excellent biocompatibility and tissue integration.

Bnefits

High concentration of ultrapure hyaluronic acid: 90 mg HA in a 2 ml pre-filled syringe (45 mg high-molecular-weight HA + 45 mg low-molecular-weight HA), one of the highest HA contents available for an injectable biorestructuring device.
Developed using NAHYCO hybrid technology to form stabilised hybrid cooperative complexes (HCC) of high- and low-molecular-weight HA via a patented thermal process, without BDDE or other chemical cross-linkers.
Specifically indicated for lipolifting and restoration of facial adipose tissue, addressing deep structural ageing changes such as midface hollows, contour loss and deep laxity.
Provides deep hydration and structural support, regenerating superficial fat compartments and improving firmness, elasticity and overall tissue tone.
Improves skin texture and reduces the appearance of wrinkles and deep slackness while preserving a natural look, rather than producing a traditional filler-type volumising effect.
Acts at the level of subcutaneous fat to restore volume and support, while also enhancing the quality and compactness of overlying skin.
Demonstrates excellent biocompatibility and tolerance due to the absence of chemical modification and the use of ultrapure, biofermented hyaluronic acid.
Supported by clinical and observational studies showing effective restoration of lateral cheek fat compartments, improved midface contours and maintained benefits over several months with a good safety profile.

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Usage

PROFHILO STRUCTURA is a Class III medical device strictly for medical use and must only be administered by qualified healthcare professionals with appropriate training in facial anatomy and cannula-based injectable techniques.
Before use, verify that the outer carton and sterile blister are intact and that the product is within the labelled expiry date. Do not use if packaging is damaged or if the gel appears cloudy, discoloured or contains visible particles.
Perform a full medical history and facial assessment to determine suitability, focusing on patterns of fat loss (e.g. lateral cheek hollows, midface sinking or sagging) and overall skin quality.
Under aseptic conditions, remove the syringe from its blister and attach the recommended TSK cannula (e.g. 22G x 50 mm or 25G x 38 mm) using the corresponding pre-bore needle entry point, as per training and manufacturer guidance.
PROFHILO STRUCTURA is injected into the superficial fat compartments of the face using retrograde cannula techniques. Common approaches include treating the preauricular area and zygomatic arch for sinkers and saggers, respecting anatomical safety zones and avoiding major vessels.
Typical treatment protocol (according to clinical studies and manufacturer guidance) consists of two Profhilo Structura sessions of 2 ml each, spaced approximately 4 weeks (30 days) apart, with product distributed between both hemifaces (e.g. 1 ml per side).
Injection depth should target the intended fat compartments rather than the dermis alone; avoid intravascular, intramuscular or intradermal-only injection when adipose restoration is the objective.
Following injection, gentle moulding may be performed if required, avoiding aggressive massage or excessive pressure.
Advise the patient to avoid makeup on the treated area for several hours post procedure and to refrain from intense physical exercise, extreme temperatures (saunas, steam rooms, hot baths), and direct UV or sunbed exposure for a few days.
Instruct the patient to report any unusual pain, blanching, prolonged redness, swelling, nodules or other concerning symptoms promptly.
Single-use only: any remaining product in the syringe after the procedure must be discarded. Do not resterilise or reuse the syringe or cannula. Dispose of all sharps in approved containers in accordance with local regulations.

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PROFHILO STRUCTURA IBSA (1 x 2 ml)

Description