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Dermaqual REJUVEYES – Advanced Peptide Complex + HA

Dermaqual REJUVEYES – Advanced Peptide Complex + HA

Dermaqual

Cosmetic / Mesotherapy solution
  • Produced by Dermaqual, a Paris Based laboratory specializing in aesthetic and cosmetic mesotherapy solutions for professional use.
  • Intended for use in clinical or aesthetic practice settings by qualified professionals in compliance with local regulations governing mesotherapy and periocular treatments.
  • Not presented as a licensed medicinal product; regulatory classification may vary by country (commonly positioned as a professional cosmetic/mesotherapy solution).
Under-eye peptide & hyaluronic acid meso-cocktail

Description

REJUVEYES is an advanced under-eye mesotherapy cocktail developed by Dermaqual, combining skin-loving hyaluronic acid with a complex of three biomimetic peptides and vascular-strengthening actives. It is specifically formulated to address key periocular concerns, including puffiness, dark circles, fine lines and wrinkles, dehydration and loss of firmness. The formula improves microcirculation and capillary function, reinforces the extracellular matrix, boosts collagen and elastin production, and delivers intensive hydration to the delicate eye contour. Supplied as sterile 5 ml vials for professional use, it is intended for needle and non-needle mesotherapy, microneedling or other meso-delivery techniques performed by trained practitioners.

Bnefits

  • Targets multiple under-eye concerns in one meso-cocktail: puffiness, dark circles, fine lines, wrinkles, and dehydration.
  • Features hyaluronic acid to boost hydration, plump the skin and improve the appearance of fine lines.
  • Contains a complex of three peptides that stimulate collagen production, improve firmness, tone and elasticity around the eye.
  • Includes vascular-protective actives (e.g. troxerutin, chrysin, ginkgo biloba and cynara scolymus extracts) to improve microcirculation and strengthen capillary walls.
  • Helps reduce periocular edema and the appearance of under-eye bags by improving lymphatic drainage and vascular tone.
  • Brightens the eye contour by reducing the appearance of dark circles and dullness.
  • Supports extracellular matrix integrity and capillary function to provide a smoother, more youthful eye area.
  • Designed for the delicate under-eye area, with a texture suitable for controlled mesotherapy delivery.
  • Can be integrated into anti-aging, brightening and eye-rejuvenation protocols as a targeted treatment.
  • Suitable for most skin types when used by professionals within appropriate mesotherapy protocols.

Indications

  • Periocular dark circles (vascular and pigment-associated appearance).
  • Under-eye puffiness and bags related to fluid retention and microcirculatory impairment.
  • Fine lines and wrinkles around the eyes, including crow’s feet and tear-trough fine lines.
  • Dehydrated, dull, tired-looking under-eye skin lacking luminosity and smoothness.
  • Loss of firmness and elasticity in the eye contour with early signs of skin laxity.
  • Supporting rejuvenation after eye-area treatments where improved microcirculation and ECM support are beneficial.
  • Areas indicated for use: under and around the eyes (inferior eyelid and periocular area only).

Composition

  • Aqua / Water
  • Alcohol
  • Propylene Glycol
  • Butylene Glycol
  • Glycerin
  • Magnesium Ascorbyl Phosphate (stable Vitamin C derivative)
  • Sodium Hyaluronate (Hyaluronic Acid)
  • Steareth-20
  • Coumarin
  • Troxerutin
  • Cynara Scolymus (Artichoke) Leaf Extract
  • Ginkgo Biloba Leaf Extract
  • Potassium Sorbate
  • Methylsilanol Mannuronate (Organic Silicon derivative)
  • Chlorhexidine Digluconate
  • N-Hydroxysuccinimide
  • Phenoxyethanol
  • Chrysin
  • Palmitoyl Tripeptide-1
  • Acetyl Tetrapeptide-5
  • Palmitoyl Tetrapeptide-7
  • Sorbic Acid

Formulation

  • Advanced peptide complex plus hyaluronic acid mesotherapy solution tailored for the eye contour.
  • Water-glycol base with humectants (glycerin, propylene glycol, butylene glycol) to enhance hydration and penetration.
  • Biomimetic peptide complex (Palmitoyl Tripeptide-1, Acetyl Tetrapeptide-5, Palmitoyl Tetrapeptide-7) to support collagen synthesis, reduce puffiness and improve elasticity.
  • Hyaluronic acid (sodium hyaluronate) for moisture retention, plumping and smoothing of fine lines.
  • Vasoactive and antioxidant actives (troxerutin, chrysin, ginkgo biloba, artichoke leaf extract, magnesium ascorbyl phosphate) to improve microcirculation, reduce oxidative stress and support even skin tone.
  • Organic silicon (methylsilanol mannuronate) to help reinforce the extracellular matrix and dermal architecture.
  • Preserved with phenoxyethanol, potassium sorbate and sorbic acid, with chlorhexidine digluconate as an antiseptic component for solution stability.

Packaging

  • Standard manufacturer presentation: box containing 5 sterile vials × 5 ml (0.17 fl. oz.) each.
  • Some distributors sell individual 5 ml vials taken from manufacturer boxes for clinic use.
  • Each vial is labelled with product name (REJUVEYES – Advanced Peptide Complex + HA), batch/lot number, and expiry date.
  • Vials are packaged in a protective outer carton suitable for professional storage conditions.

Usage

  • For professional use only; to be administered by licensed medical or aesthetic practitioners experienced in mesotherapy and periocular treatments.
  • Before treatment, perform a detailed assessment of the under-eye area and patient history, including allergies and contraindications.
  • Cleanse and disinfect the periocular skin thoroughly, ensuring the eye is protected and no product enters the conjunctival sac.
  • Apply using appropriate mesotherapy techniques for the eye area: micro-injections (nappage, point-by-point), microneedling, non-needle mesotherapy, or other meso-delivery methods according to clinic protocol and local regulations.
  • Inject or apply only into the superficial to mid-dermal plane of the under-eye and periocular region, carefully avoiding intravascular injection and respecting anatomical safety zones.
  • Use small aliquots in a grid or linear pattern to evenly treat the under-eye region; do not overfill or inject boluses in risky areas.
  • Typical in-clinic use follows a multi-session protocol (for example: an intensive phase of weekly or bi-weekly sessions for several treatments, followed by spacing to monthly sessions, then maintenance every few months), adjusted based on patient response and the official Dermaqual mesotherapy guidelines.
  • Use each vial for a single patient only; any unused remainder must be discarded and not stored or reused.
  • After treatment, gently dab the area without strong massage; advise the patient to avoid rubbing the eyes, heat exposure, or strenuous exercise for the rest of the day.
  • Recommend the patient use broad-spectrum sun protection and follow appropriate periocular skincare to maintain results and reduce further photo-induced damage.
  • Instruct patients to report promptly any persistent pain, swelling, visual disturbance, or signs of infection.

Contraindications

  • Known hypersensitivity or allergy to any of the components (e.g. hyaluronic acid, peptides, plant extracts, preservatives, chlorhexidine).
  • Active skin infections, inflammation, dermatitis, eczema, or herpes lesions in or near the periocular treatment area.
  • Compromised periocular skin barrier, open wounds, or recent surgical procedures around the eyes without complete healing.
  • History of severe allergic reactions or anaphylaxis to injectable mesotherapy products or similar cocktail components.
  • Pregnancy and breastfeeding (generally considered cautionary for aesthetic mesotherapy due to limited safety data; many clinics avoid treatment in these cases).
  • Severe systemic illness, uncontrolled autoimmune diseases, or immune deficiency without specialist clearance.
  • Patients using medications or with conditions that significantly increase the risk of bruising or bleeding (e.g. uncontrolled coagulopathies), unless evaluated and cleared by a physician.
  • Any condition where periocular mesotherapy is contraindicated according to local medical guidelines or Dermaqual’s official recommendations.

Adverse Effects

  • Transient erythema (redness), mild swelling and sensitivity at injection or microneedling sites under and around the eyes.
  • Temporary bruising or small hematomas due to vascular density in the periocular area, especially when injectable techniques are used.
  • Mild stinging, burning or tightness during or shortly after treatment, particularly on sensitive skin.
  • Occasional dryness or flakiness if post-procedure care and hydration are inadequate.
  • Risk of post-inflammatory hyperpigmentation in predisposed individuals if the area is not protected from sun exposure after treatment.
  • Rare allergic or hypersensitivity reactions to one or more ingredients, potentially requiring discontinuation and medical management.
  • Very rare but serious complications associated with eye-area procedures, such as infection, prolonged edema, or vascular complications, particularly if improper technique is used; these require urgent medical evaluation.
  • As with all periocular mesotherapy, adverse effects are minimized when correct sterile technique, anatomical knowledge and appropriate patient selection are respected.

Storage Conditions

  • Store in a cool, dry place away from direct sunlight and sources of heat.
  • Keep vials in their original carton until use to reduce exposure to light and environmental factors that may degrade active ingredients (e.g. vitamin C derivative, plant extracts).
  • Do not freeze; freezing may destabilize the formulation.
  • Do not use after the expiry date printed on the vial and outer packaging.
  • Do not use if the vial, seal or packaging is damaged, leaking or shows signs of compromised sterility.
  • Once opened, use immediately for a single session and single patient; discard any unused remainder.

Duration

A complete under-eye mesotherapy course with REJUVEYES is typically conducted over multiple sessions (commonly an intensive phase over several weeks, followed by consolidation and maintenance sessions every 1\u20133 months). The visible benefits in terms of puffiness, dark circles and fine lines are usually maintained with periodic maintenance treatments, but exact duration depends on individual skin condition, lifestyle and protocol used.

Onset

Hydration and a smoother feel of the under-eye skin can appear shortly after initial sessions, while more pronounced improvements in dark circles, puffiness, and fine lines are generally progressive and become more evident over the course of several treatments as collagen production and microcirculation improve.

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