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Exoblanc COS Range

Exoblanc COS Range

Exoblanc

Professional aesthetic skin booster
  • Marketed as a professional cosmetic/aesthetic skin booster for use with microneedling and mesotherapy; not presented as a licensed medicinal product in the UK.
  • Manufactured under cosmetic or cosmeceutical Good Manufacturing Practice (GMP) standards appropriate to the markets where it is distributed.
  • Use in clinics should comply with local regulations governing aesthetic procedures, infection control, sharps handling and patient consent.
  • Practitioners are responsible for ensuring that their use of Exoblanc COS PN aligns with professional guidelines and any applicable national regulatory requirements for injectable or needling procedures.
Exosome & polynucleotide skin booster ampoule

Description

Exoblanc COS PN (Single 1 x 4ml) is a professional-grade skin booster ampoule that combines PDRN, PN (polynucleotides) and exosomes to promote skin renewal, hydration and elasticity. Designed for use with microneedling and mesotherapy by trained professionals, this advanced formulation works at a cellular level to support cell regeneration and tissue repair, stimulate fibroblasts and enhance collagen absorption. The result is improved skin texture, elasticity and radiance with a visible reduction in fine lines and wrinkles. Supplied as a single 4ml vial, Exoblanc COS PN is ideal for smaller treatments, patch testing, or introducing new clients to exosome and polynucleotide-based rejuvenation, and can be integrated into wider Exoblanc protocols for intensive skin repair and anti-ageing support.

Bnefits

  • Promotes cell regeneration and tissue repair with a synergy of PDRN, PN and exosomes.
  • Stimulates fibroblasts and enhances collagen absorption, supporting firmer, more elastic skin.
  • Improves skin elasticity, hydration and overall texture, helping to restore a smoother, more supple complexion.
  • Reduces the appearance of fine lines and wrinkles as part of a professional rejuvenation protocol.
  • Delivers powerful hydration and barrier support, particularly beneficial for dry, sensitive or compromised skin.
  • Exosome-based technology targets cellular communication pathways to optimise repair and regeneration.
  • High-performance formulation designed specifically for use with microneedling and mesotherapy treatments.
  • Single 4ml vial format is convenient for smaller treatment areas, patch tests or first-time client trials.

Indications

  • Skin in need of regeneration and repair following ageing, environmental stress or aesthetic procedures (as directed by a professional).
  • Dry, dehydrated or moisture-depleted skin with compromised barrier function.
  • Loss of elasticity, firmness and resilience in the skin.
  • Fine lines and early to moderate wrinkles requiring visible softening and support.
  • Dull, uneven or rough skin texture requiring smoothing and revitalisation.
  • Skin suitable for professional microneedling or mesotherapy treatments using exosome and polynucleotide-based boosters.

Composition

  • Key active components (as described across manufacturer and distributor sources for Exoblanc COS PN / COS PN+):
  • PDRN (Polydeoxyribonucleotide) – typically present as Sodium DNA; supports DNA repair processes, cell turnover and dermal regeneration.
  • Polynucleotides (PN) – long-chain DNA fragments that promote tissue repair, enhance fibroblast activity and support collagen and elastin synthesis.
  • Exosomes – advanced vesicle-based technology derived from carefully selected sources (e.g. probiotic or plant cell extracellular vesicles in the Exoblanc range) that deliver signalling molecules to support cellular repair and rejuvenation.
  • Hydrating and barrier-supportive components commonly associated with Exoblanc COS PN formulations: Sodium Hyaluronate, Soluble Proteoglycan and Mannitol, which help attract and retain moisture, support extracellular matrix structure and provide antioxidant defence.
  • Additional excipients, stabilisers and solvents (not fully disclosed in public listings) to ensure isotonicity, pH balance and stability for professional microneedling/mesotherapy use.

Formulation

  • Sterile cosmetic/esthetic solution in an ampoule / vial intended for professional topical or transdermal delivery via microneedling and mesotherapy techniques.
  • Clear, low-viscosity liquid designed for optimal glide and penetration when used with professional devices.
  • Multifactorial skin booster formula combining polynucleotides, PDRN and exosome technology with hydrating and barrier-supportive actives.
  • Single-use 4ml vial to help maintain product integrity and minimise contamination risk during professional treatments.

Packaging

  • Single 4ml glass vial (ampoule) of Exoblanc COS PN skin booster.
  • Supplied as an individual unit (1 x 4ml) for smaller treatments, patch testing or introductory protocols.
  • Vial typically packaged in a branded carton or protective packaging with product identification and basic instructions.
  • Also available in multi-vial packs (e.g. 6 x 4ml) for regular professional use; the single-vial SKU corresponds to the individual unit format.

Usage

  • For professional use only by suitably qualified and trained practitioners in accordance with local regulations.
  • Intended to be used as a skin booster in conjunction with approved microneedling or mesotherapy techniques and compatible devices.
  • Prior to use, a full medical and aesthetic consultation, skin assessment and patch testing (where appropriate) should be undertaken.
  • The skin should be cleansed and prepared according to clinic protocol before the procedure.
  • The contents of a single 4ml vial are used during the treatment session as directed by the practitioner, in line with device manufacturer guidelines and Exoblanc treatment protocols.
  • Any unused product from an opened vial should be discarded in accordance with clinic hygiene and sharps/waste disposal policies; vials are designed as single-use units.
  • Clients should be provided with tailored aftercare advice, including sun protection and post-procedure skincare, as determined by the treating professional.
  • Self-administration or home injection is not recommended and may be unsafe.

Contraindications

  • Known hypersensitivity or allergy to any component of the product, including polynucleotides, Sodium DNA (PDRN), exosome-related components or excipients.
  • Active skin infections, inflammatory dermatoses or open wounds at the intended treatment site.
  • History of keloid or hypertrophic scarring in the proposed treatment area, unless the practitioner deems treatment appropriate with caution.
  • Severe systemic conditions or autoimmune diseases where microneedling or mesotherapy are contraindicated, according to medical judgement.
  • Pregnancy or breastfeeding, unless a medical professional experienced in aesthetics specifically approves treatment after risk–benefit assessment.
  • Ongoing use of systemic medications or therapies that significantly impair healing or increase bleeding risk (e.g. certain anticoagulants, high-dose corticosteroids), unless managed in consultation with the prescribing physician.
  • Any general contraindications to microneedling or mesotherapy as defined by professional guidelines and device manufacturers.

Adverse Effects

  • Transient erythema (redness), oedema (swelling), pinpoint bleeding and mild discomfort at the treatment site, typical of microneedling and mesotherapy procedures.
  • Temporary dryness, tightness or mild flaking as the skin renews.
  • Occasional bruising or petechiae, especially in more vascular areas or with deeper needle penetration.
  • Risk of infection if aseptic technique is not strictly observed during treatment.
  • Rare hypersensitivity or allergic reactions to product components, potentially presenting with persistent redness, swelling, itching, rash or urticaria.
  • Very rare risk of post-inflammatory hyperpigmentation or scarring if procedures are performed inappropriately or on unsuitable skin types/conditions.
  • Any suspected serious adverse events should prompt immediate cessation of use and medical evaluation.

Storage Conditions

  • Store in a cool, dry place at controlled room temperature, typically between 2 °C and 25 °C, as per distributor guidance.
  • Protect from direct sunlight and excessive heat or freezing conditions.
  • Keep vials in their original outer packaging until use to protect from light and contamination.
  • Do not use if the vial is damaged, cracked, leaking or if the solution appears cloudy or discoloured.
  • Once opened, use immediately during a single treatment session and discard any remaining product; do not re-use opened vials.
  • Keep out of reach of children.

Duration

Treatment schedules are determined by the treating professional based on the client\u2019s skin condition and goals. Exoblanc COS PN is commonly used in a course of sessions spaced several weeks apart (for example, a series of microneedling or mesotherapy treatments), with maintenance sessions as needed. The single 4ml vial format is suited to individual sessions, patch testing or small-area treatments.

Onset

Hydration and surface comfort may improve shortly after treatment, with progressive enhancements in texture, elasticity and fine lines typically observed over subsequent weeks as collagen and tissue remodelling occur. Exact onset and degree of effect depend on individual skin condition, treatment protocol and adjunctive skincare.

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