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Lapiena NMN+ 1 x 5ml

Lapiena NMN+ 1 x 5ml

Lapiena

Skin booster / mesotherapy solution
  • Labelled "Made in Korea" and marketed as a cosmetic/professional skin booster rather than an MHRA Licensed medicinal product.
  • Distributed in the UK and EU through aesthetics wholesalers under cosmetic, mesotherapy or skin Booster categories, rather than as a CE Marked injectable medical device.
  • Manufactured under Korean cosmetic and aesthetic product quality frameworks; specific GMP or ISO certifications are not explicitly listed in publicly available product descriptions.
  • Positioned within Lapiena’s professional Pro Skin range alongside other clinic Focused boosters and cosmeceutical products.
NAD+ precursor-based NMN cosmetic skin booster vial for anti-ageing and cellular revitalisation

Description

Lapiena NMN+ 1 x 5ml is a professional NAD+ precursor-based skin booster designed to support healthy ageing, cellular vitality and visible skin rejuvenation from within. Each 5 ml amber glass vial contains a concentrated solution powered by Nicotinamide Mononucleotide (NMN) alongside complementary actives such as NAD+, niacinamide, adenosine, PDRN, panthenol and phosphate-buffered excipients. By replenishing intracellular NAD+ levels, it aims to enhance mitochondrial energy production, support DNA repair and activate sirtuin pathways associated with longevity. Clinically oriented marketing describes benefits for overall skin health, hydration, texture, fine lines and radiance. The product can be integrated into aesthetic protocols as a topical solution, used with microneedling or other device-based treatments, and, according to Lapiena’s own instructions, in microinjection protocols performed only by qualified professionals, while some distributors market it strictly as a topical cosmetic solution depending on local regulations.

Bnefits

  • Supports and sustains intracellular NAD+ levels over time via NMN and NAD+ to promote cellular energy metabolism and longevity pathways.
  • Improves overall skin quality, including texture, tone and radiance, by supporting renewal and repair at the cellular level.
  • Combats visible signs of ageing such as dullness, fine lines and loss of firmness through enhanced collagen and elastin stimulation and cell regeneration.
  • Enhances metabolic activity and ATP production in skin cells, helping to reduce cellular fatigue and promote long-term vitality.
  • Promotes skin hydration and barrier repair via panthenol, PDRN, hyaluronic acid complex and other hydrating/regenerative ingredients.
  • Helps control oxidative stress and supports DNA repair mechanisms associated with healthier, more resilient skin.
  • May support systemic wellbeing and cognitive function as part of an NAD+-focused regimen, as described in some distributor marketing, although primary positioning is as a cosmetic skin booster.
  • Versatile administration options: suitable for topical application, use with microneedling or other energy-based devices, and (per Lapiena’s protocol) professional microinjection, allowing integration into a wide range of clinic treatment plans.
  • Formulated with a near-neutral pH (approximately 6.8–7.4) and phosphate buffer to maintain ingredient stability and skin compatibility.
  • Designed as a high-performance NAD+ booster for clients interested in long-term skin rejuvenation, improved mitochondrial health and advanced anti-ageing care.

Indications

  • Overall skin health optimisation and cosmetic skin rejuvenation in adults.
  • Visible anti-ageing concerns, including fine lines, loss of radiance and mild loss of firmness or elasticity.
  • Dull, tired or fatigued skin lacking glow and vitality.
  • Photoaged skin with early signs of sun damage when used as part of a broader skincare and procedural plan.
  • Compromised skin barrier and dehydration, where improved hydration and repair are desired.
  • Supportive post-procedure care for skin recovering from professional treatments such as microneedling, RF, HIFU or fractional laser, when used topically to enhance regeneration (following practitioner judgment and local guidelines).
  • Adjunctive cosmetic treatment for patients seeking NAD+/NMN-based approaches to slow visible ageing and support cellular repair pathways.
  • Clinic-based mesotherapy-style protocols aimed at improving texture, elasticity and overall skin quality on the face and other cosmetically relevant areas.

Composition

  • Nicotinamide Mononucleotide (NMN) – NAD+ precursor that increases intracellular NAD+ and supports cellular energy and DNA repair.
  • Nicotinamide Adenine Dinucleotide (NAD+) – essential coenzyme involved in mitochondrial ATP production, DNA repair and sirtuin activation.
  • Niacinamide (Vitamin B3) – brightens dull skin, supports barrier function, regulates sebum and further supports NAD+ metabolism.
  • Adenosine – promotes collagen synthesis, helps reduce fine lines and supports elastic, smoother skin.
  • PDRN (Polydeoxyribonucleotide / Salmon DNA extract) – supports tissue regeneration, healing and improved skin firmness.
  • Panthenol (Provitamin B5) – provides deep hydration, soothes irritation and strengthens the skin’s moisture barrier.
  • Hyaluronic Acid complex – helps lock in moisture, improve plumpness and support dermal matrix structure (listed in some distributor technical descriptions).
  • Sodium DNA – nucleic-acid derivative supporting regenerative and hydrating effects (as per some distributor information).
  • Disodium Phosphate – buffering agent contributing to a near-neutral pH and formulation stability.
  • Sodium Phosphate – buffering component maintaining physiological pH and compatibility.
  • Water and standard cosmetic excipients (not exhaustively listed on public materials) forming a sterile, phosphate-buffered aqueous solution.

Formulation

  • Clear, aqueous, phosphate-buffered solution containing NMN, NAD+ and supportive cosmetic actives for professional skin booster use.
  • Near-neutral pH (approximately 6.8–7.4) formulated to maintain NMN and NAD+ stability and optimise skin compatibility.
  • Liquid solution supplied in sterile 5 ml amber glass vials with a sealed cap, suitable for topical application, device-assisted delivery (e.g., microneedling) and, according to Lapiena, microinjection by trained professionals.
  • Cosmetic/skin booster formulation designed for use on the face and other cosmetically relevant areas as part of professional aesthetic protocols.

Packaging

  • Single 5 ml amber glass vial (1 x 5 ml) supplied in a branded Lapiena NMN+ outer box labelled as a premium NAD+ skin booster and marked "Made in Korea".
  • Vial closed with a sealed cap suitable for aseptic withdrawal of product in clinic settings.
  • Also available in multi-vial box formats (e.g., 10 x 5 ml pack) through Lapiena and other distributors, although the LPG Clinics Wholesale SKU referenced here is a single 5 ml vial.
  • External packaging includes product name, volume, usage category (skin booster / NAD+ booster), manufacturing origin and distributor branding.

Usage

  • Lapiena NMN+ is intended for professional use in aesthetic clinics and by trained skincare practitioners; it should not be self-injected by patients or used outside appropriate professional supervision.
  • Before use, review the full product information supplied by Lapiena or the distributor, screen for allergies to any listed ingredients (e.g., NMN, niacinamide, adenosine, PDRN, panthenol) and assess skin condition and suitability.
  • Store the vial correctly and allow it to reach room temperature before application.
  • For topical cosmetic use: apply an appropriate amount of solution to cleansed skin, either as a standalone booster or layered within a professional skincare protocol; gently massage until absorbed, avoiding contact with eyes and mucous membranes.
  • For microneedling or device-assisted delivery: apply Lapiena NMN+ during or immediately after microneedling, RF, HIFU, fractional laser or similar treatments as per clinic protocol to enhance penetration and support regeneration; observe device manufacturer guidelines and avoid over-treatment.
  • According to Lapiena’s own protocol, when used as an injectable booster, only qualified medical professionals should perform treatment using a very fine 34G needle with vertical or slightly angled microinjections into the dermis, administering approximately 0.01–0.03 ml per point across roughly 100–200 points per side of the face to ensure a dense, even distribution.
  • Do not mix Lapiena NMN+ in the same syringe with other injectable products; if combining with other agents in a protocol, apply them sequentially according to professional judgment.
  • Use one 5 ml vial per full-face session, in line with distributor guidance; any remaining solution from an opened vial should not be stored for later use unless explicitly permitted by the manufacturer’s instructions.
  • Example treatment plan from distributor guidance: 2–3 sessions in the first month (one vial per session), followed by maintenance sessions every 2–3 months, adjusted based on patient response and practitioner assessment.
  • In markets or settings where distributors specify "for topical cosmetic use only" and "not for injection", follow local labelling, regulatory requirements and professional standards by limiting use to topical and device-assisted (non-injectable) applications.
  • Advise clients to avoid makeup immediately after intensive procedures, minimise sun and UV exposure, and avoid alcohol, smoking, sauna and very hot environments for at least 24 hours after treatment, in line with K Derma and other distributor safety tips.
  • Instruct clients to seek medical advice if they experience significant or persistent redness, irritation, swelling, pain, or any unexpected reaction after treatment.

Contraindications

  • Known hypersensitivity or allergy to any ingredient in the formula (e.g., NMN, niacinamide, adenosine, PDRN, panthenol, hyaluronic acid or other excipients).
  • Active skin infections, inflammatory dermatoses or open wounds at or near the intended treatment area (e.g., bacterial infection, active herpes simplex, severe dermatitis).
  • Compromised skin barrier or significant irritation in the planned treatment area until adequately healed.
  • Pregnancy or breastfeeding, unless a qualified healthcare professional has assessed the risk–benefit and explicitly approved use (many distributors advise caution or consultation before use).
  • History of severe allergic reactions or anaphylaxis to cosmetic injectables or similar skin boosters.
  • For injection-based protocols: use in individuals without appropriate medical assessment or in settings where injectable aesthetic treatments are not legally permitted.
  • Inappropriate use on mucous membranes, in the eyes or intravascularly; the product is intended for dermal/tissue use, not for intravenous or intra-arterial administration.
  • Use in patients with uncontrolled systemic illness or acute febrile conditions, unless cleared by a medical professional.
  • Any local regulatory or labelling restrictions that classify the product as "topical cosmetic use only" and prohibit injection in that jurisdiction.

Adverse Effects

  • For topical application: transient redness, mild irritation, tingling, itching or dryness at the application site, usually resolving spontaneously.
  • For microneedling or device-assisted protocols: expected post-procedure reactions such as erythema, mild swelling, pinpoint bleeding, temporary roughness or tightness of the skin.
  • For any injectable use by professionals: common injection-related reactions, including local redness, swelling, tenderness, bruising or small papules at injection points, typically settling within a few days.
  • Possible temporary worsening of dryness or flaking if barrier-compromised skin is treated too aggressively or without suitable supportive skincare.
  • Allergic or hypersensitivity reactions to NMN, niacinamide, PDRN, panthenol or other components, which may manifest as persistent redness, itching, oedema or rash; treatment should be stopped and medical advice sought if such reactions occur.
  • In rare cases, more significant inflammatory responses, nodules or prolonged irritation may develop, particularly if used on sensitised skin or combined with aggressive procedures.
  • If misused or injected improperly by unqualified persons, there is potential for more serious complications associated with any injectable skin booster, such as infection, significant bruising, tissue damage or, very rarely, vascular compromise.

Storage Conditions

  • Store below 30 °C as indicated by distributor guidance.
  • Keep vials out of direct sunlight and away from excessive heat sources to preserve NMN and NAD+ stability.
  • Store in a dry place in the original outer packaging until use.
  • Do not freeze the product and avoid large temperature fluctuations.
  • Keep out of reach of children and unauthorised persons.
  • Use the vial before the expiry date printed on the packaging and do not use if the vial or packaging appears damaged or compromised.

Duration

Marketing and distributor information describe Lapiena NMN+ as supporting long-term vitality and sustained improvement in skin quality when used in a series. A typical protocol involves 2\u20133 sessions in the first month using one 5 ml vial per full-face session, followed by maintenance every 2\u20133 months. Visible benefits such as improved texture, hydration and radiance generally develop over several weeks; the exact duration of effect and maintenance frequency depend on individual skin condition, lifestyle, and the overall treatment plan.

Onset

Many patients experience an immediate or early improvement in skin radiance and hydration after initial treatment, with progressive benefits in texture, elasticity and visible signs of ageing emerging over subsequent weeks as cellular energy, collagen synthesis and repair pathways are supported through repeated sessions.

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