ISDIN A.G.E Reverse Night ISDINCEUTICS Rejuvenate 50ml
ISDINCEUTICS
Cosmetic dermocosmetic anti-aging night creamMelatonin-based anti-aging night cream for face, neck and d\u00e9collet\u00e9
Certifications
- Marketed as a cosmetic dermocosmetic anti Aging night cream; no UK MHRA medicinal product licence is publicly listed for this product.
- No CE or UKCA medical device marking is publicly referenced for A.G.E Reverse Night; it is positioned as a cosmetic skincare product rather than a medical device.
- Listed by multiple pharmacies and dermocosmetic retailers as a dermatologically tested cosmetic product suitable for all skin types.
- ISDIN is widely described as a dermocosmetic company offering products that combine dermatology and cosmetics; corporate communications reference international quality and safety standards for skincare products (these are brand Level rather than product Specific).
- Marketed as a cosmetic dermocosmetic anti Aging night cream; no UK MHRA medicinal product licence is publicly listed for this product.
- No CE or UKCA medical device marking is publicly referenced for A.G.E Reverse Night; it is positioned as a cosmetic skincare product rather than a medical device.
- Listed by multiple pharmacies and dermocosmetic retailers as a dermatologically tested cosmetic product suitable for all skin types.
- ISDIN is widely described as a dermocosmetic company offering products that combine dermatology and cosmetics; corporate communications reference international quality and safety standards for skincare products (these are brand Level rather than product Specific).
Melatonin-based anti-aging night cream for face, neck and d\u00e9collet\u00e9
Description
ISDIN A.G.E Reverse Night ISDINCEUTICS Rejuvenate 50ml is an anti-aging facial night cream formulated by ISDIN under the ISDINCEUTICS line. It is described as a moisturizing and restorative night cream based on melatonin that helps repair the skin overnight, remodel the facial oval, and reduce wrinkles and expression lines. The formula combines melatonin, carnosine, Helichrysum italicum extract, cross-linked hyaluronic acid, betaine, niacinamide and matrikine-like peptides in a rich yet cosmetic-texture cream designed for face and neck (and often décolleté). Melatonin helps fight oxidative damage accumulated during the day and stimulates the skin’s natural antioxidant defenses while sleeping. Carnosine delays the formation of advanced glycation end products (AGEs) that can reduce collagen and elastin functionality, while Helichrysum italicum extract stimulates the release of calming molecules to promote a pleasant sensation of well-being. The product is marketed as suitable for all skin types, including mature and photoaged skin, and is intended to be used at night, ideally alongside A.G.E Reverse Day as a complementary anti-aging regimen.
Bnefits
- Moisturizing and restorative night cream formulated with melatonin that fights oxidative damage accumulated during the day and stimulates the skin’s natural antioxidant defenses while you sleep.
- Helps repair the skin overnight and supports visible regeneration for a more rested, revitalized appearance.
- Remodels the oval of the face and improves the appearance of facial contours with continued use.
- Reduces the appearance of wrinkles and expression lines, contributing to a smoother, more youthful-looking complexion.
- Contains carnosine, which delays the phenomenon of advanced glycation and helps maintain the functionality of collagen and elastin.
- Includes Helichrysum italicum extract, which stimulates the release of calming molecules to provide a pleasant sensation of well-being and support skin comfort.
- Incorporates cross-linked hyaluronic acid and betaine to boost hydration and help maintain skin suppleness and elasticity.
- Niacinamide and other dermocosmetic actives support an even, luminous tone and healthier-looking skin.
- Dermatologically tested cosmetic formula suitable for use as part of an anti-aging night routine.
- Designed to be used in combination with A.G.E Reverse Day for complementary remodeling care by day and reparative care at night.
Indications
- Cosmetic management of visible signs of skin aging, including wrinkles and expression lines.
- Night-time moisturizing and restorative care for face and neck (and often décolleté) in adults.
- Improvement of skin firmness and the appearance of facial contours (oval of the face).
- Support for skin exposed to oxidative stress and environmental aggressions during the day.
- Anti-glycation support to help maintain the functionality of collagen and elastin through the presence of carnosine.
- Soothing and comfort care for skin requiring a pleasant sensation of well-being, supported by Helichrysum italicum extract.
- Use as an anti-aging night cream in dermocosmetic and aesthetic medicine routines, especially when combined with A.G.E Reverse Day and other ISDINCEUTICS products.
Composition
- Full INCI list as published in official and professional product information: Aqua (Water), Glycerin, Propanediol, Niacinamide, Betaine, Olus Oil (Vegetable Oil), Caprylic/Capric Triglyceride, Silica, Dimethicone, Hydrogenated Polyisobutene, Isodecyl Neopentanoate, Octyldodecanol, Stearyl Alcohol, Dipentaerythrityl Hexacaprylate/Hexacaprate, Tridecyl Trimellitate, Alcohol Denat., Butylene Glycol, Phenylpropanol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Panthenol, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Tridecyl Stearate, Carnosine, Parfum (Fragrance), Neopentyl Glycol Dicaprylate/Dicaprate, Melatonin, Cetyl Alcohol, Glyceryl Stearate, Pentylene Glycol, Sodium Hyaluronate Crosspolymer, Disodium EDTA, PEG-75 Stearate, PEG-8, Carbomer, Polysorbate 20, Sodium Lactate, Ceteth-20, Steareth-20, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Tocopherol, Ascorbyl Palmitate, Magnesium Chloride, Helichrysum Italicum Extract, Ascorbic Acid, Citric Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, CI 15985 (Yellow 6), CI 19140 (Yellow 5).
- Key highlighted actives: Melatonin (stimulates skin antioxidant defenses to combat oxidative damage accumulated during the day), Carnosine (anti-glycation active that acts on sugar molecules to delay the formation of advanced glycation end products), Helichrysum Italicum extract (stimulates release of calming molecules and contributes to skin comfort and barrier support).
- Hydration and barrier-support ingredients include Glycerin, Betaine, Caprylic/Capric Triglyceride, cross-linked Sodium Hyaluronate and emollient oils and esters.
- Antioxidant-related ingredients include Melatonin, Tocopheryl Acetate, Tocopherol, Ascorbyl Palmitate and Ascorbic Acid.
- Peptide components include Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7 and Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate (matrikine-like peptide), supporting visible anti-aging effects.
- The formulation is presented as a cosmetic dermocosmetic product; no medicinal active ingredient regulated as a drug substance is listed.
- No parabens are listed among the ingredients in the published INCI list.
Formulation
- Topical cosmetic night cream with a rich yet cosmetic-texture formulation intended for external use on face, neck and often décolleté.
- Anti-aging dermocosmetic formula based on melatonin, carnosine, Helichrysum italicum extract, cross-linked hyaluronic acid, betaine, niacinamide and peptides.
- Designed to provide intensive overnight hydration and visible anti-wrinkle, anti-glycation and remodeling benefits while the skin is in its natural nocturnal repair phase.
- Dermatologically tested cosmetic product suitable for all skin types, including mature and photoaged skin, according to pharmacy and retailer listings.
- Part of the ISDINCEUTICS REJUVENATE range and positioned as the night counterpart to A.G.E Reverse Day within ISDIN’s anti-aging routines.
- Supplied as a 50 g (50 ml) cream in a cosmetic jar format; some markets also reference a 51.5 g presentation including packaging content.
Packaging
- Supplied in a 50 ml (50 g) cosmetic jar labelled as ISDINCEUTICS A.G.E Reverse Night, typically with ISDIN/ISDINCEUTICS branding and product details.
- Retail and professional listings describe the product as "ISDINCEUTICS A.G.E Reverse Night 50ml" or "50 g" depending on market, referring to the same night cream content.
- The jar is presented in outer carton packaging carrying information such as ingredients, usage instructions, batch/lot number and expiry date (specific carton artwork details are not fully described in public sources).
- In several distributor and pharmacy documents, the product is referenced in price lists and promotional PDFs as "ISDINCEUTICS A.G.E. Reverse NIGHT 50ml" or "50g" with internal SKU codes.
- No specific reference to airless pump or special closure features is publicly provided beyond the standard cosmetic jar presentation.
Usage
- Apply every evening to clean, dry skin on the face and neck, using upward movements until completely absorbed, as described in official and distributor dosage information.
- Many pharmacy and retailer instructions extend use to the décolleté, advising application to face, neck and décolleté after cleansing and, where applicable, after serum.
- Use once daily at night as the final step in the skincare routine, after any serums or targeted treatments.
- External use only. Keep out of reach of children.
- Avoid all contact with the eyes and mucous membranes; if contact occurs, rinse thoroughly with water.
- Do not use on irritated or broken skin, as explicitly stated in distributor dosage cautions.
- If signs of irritation or intolerance appear, discontinue use and consult a healthcare professional or dermatologist.
- For optimal anti-aging results, ISDIN recommends combining A.G.E Reverse Night with A.G.E Reverse Day and other ISDINCEUTICS products as part of a complete routine.
Contraindications
- Do not use in case of known hypersensitivity or allergy to any of the listed ingredients (e.g., melatonin, carnosine, Helichrysum italicum extract, peptides, fragrance or other excipients).
- External use only; do not ingest.
- Avoid all contact with the eyes and mucous membranes; if contact occurs, rinse thoroughly with water.
- Do not use on irritated or broken skin, as stated in dosage and caution information from distributors.
- Keep out of reach of children.
- Users experiencing persistent irritation, redness or discomfort should discontinue use and consult a healthcare professional or dermatologist.
Adverse Effects
- Not publicly listed
Storage Conditions
- No specific temperature storage conditions are detailed in publicly available product information; standard cosmetic care advises storing in a cool, dry place away from direct heat sources and sunlight.
- Keep the container tightly closed when not in use to protect the integrity of the formulation.
- Keep out of reach of children.
- Do not use after the expiry date printed on the packaging.
- Discard the product if there are visible changes in colour, odour or texture suggestive of deterioration.
Duration
No fixed treatment duration is specified in available cosmetic product literature. ISDIN A.G.E Reverse Night is intended for ongoing nightly use as part of a long-term anti-aging skincare regimen. Improvements in hydration and radiance are described after regular use, with some sources citing visible benefits such as smoother, more radiant skin and reduced appearance of fine lines and wrinkles after approximately 28 days of nightly application, but there is no defined maximum duration; continued use is implied for sustained cosmetic benefits.
Onset
Not publicly listed
