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Purasomes NC150+ Skin Nutri Complex

Purasomes NC150+ Skin Nutri Complex

Purasomes

Professional exosome skin treatment
  • Developed and manufactured by Dermoaroma Italy S.R.L., a regenerative aesthetics company specialising in exosome and polynucleotide formulations.
  • Utilises multi Patented AMPLEX Plus technology combining exosomes and growth factors from ethically sourced bovine colostrum.
  • Distributed to registered clinics and pharmacies through DermaFocus and other professional aesthetic suppliers in accordance with local regulatory frameworks for exosome Based products.
Exosome-based anti-ageing skin nutri complex for microneedling

Description

Purasomes NC150+ Skin Nutri Complex is an advanced, exosome-powered regenerative treatment designed for tired, aged and photo-damaged skin. Using patented AMPLEX Plus technology, it combines 20 billion bovine colostrum-derived exosomes, 20 functional growth factors, dual molecular weight hyaluronic acid, polynucleotides (including PDRN), amino acids, vitamins, coenzymes and reducing agents to reprogram skin cells and amplify cellular performance. The complex deeply nourishes and replenishes mature, dry, distressed and damaged skin by promoting angiogenesis, new tissue formation and fibroblast activation. Clinically proven to improve skin thickness, brightness, hydration and elasticity in as little as four weeks, NC150+ amplifies collagen production, increases skin density, protects against free radicals and helps rebuild a resilient dermal framework for a more youthful appearance. It is delivered to the dermis via in-clinic microneedling as a standalone treatment, a primer for energy-based procedures or in combination with polynucleotides.

Bnefits

  • Amplifies collagen production and stimulates fibroblasts to repair skin damage and improve dermal structure.
  • Clinically proven improvements in skin thickness, brightness, hydration and elasticity in as little as four weeks.
  • Increases skin density and firmness, helping to address elastosis, fine lines and wrinkles.
  • Protects skin from harmful free radicals and oxidative stress through a rich mix of antioxidants and reducing agents.
  • Deeply moisturises skin and reduces transepidermal water loss with dual molecular weight hyaluronic acid.
  • Promotes angiogenesis (formation of new blood vessels) and new tissue formation to accelerate skin recovery.
  • Reprograms and regenerates aged, dry and distressed skin cells, restoring a healthier, more youthful appearance.
  • Acts as an excellent skin primer for energy-based treatments (e.g. lasers, RF) and enhances post-procedure recovery.
  • Can be combined with polynucleotides (e.g. Plinest) to further optimise regenerative outcomes.

Indications

  • Tired and aged skin showing signs of photoageing and chronoageing.
  • Mature, dry, distressed and damaged skin requiring deep repair and nourishment.
  • Skin with reduced density, elasticity and thickness (elastosis, fine lines, wrinkles).
  • Photo-damaged skin with dullness, loss of radiance and uneven texture.
  • Patients seeking regenerative, non-surgical anti-ageing treatments delivered via microneedling.
  • Use as a skin primer and recovery booster around energy-based procedures (e.g. laser, RF, IPL) and in combination protocols with polynucleotides.

Composition

  • 20 billion organic bovine colostrum-derived exosomes.
  • 200 mg of 20 functional growth factors.
  • 75 mg high molecular weight hyaluronic acid (HMW HA, approx. 1100–1400 kDa).
  • 75 mg low molecular weight hyaluronic acid (LMW HA, approx. 80–100 kDa).
  • PDRN (polydeoxyribonucleotide) and polynucleotides for tissue repair support.
  • 23 amino acids.
  • 10 vitamins.
  • 6 coenzymes.
  • Reducing agents (antioxidant/anti–free radical components).
  • Proprietary AMPLEX Plus technology vehicle and excipients suitable for professional dermal application.

Formulation

  • Sterile, ready-to-use exosome and growth-factor rich solution for topical delivery via microneedling.
  • Multi-patented AMPLEX Plus technology combining exosomes, growth factors, PDRN/polynucleotides, dual-weight hyaluronic acid, amino acids, vitamins and coenzymes.
  • Non-crosslinked, injectable-grade style fluid intended for percutaneous delivery into the dermis using microneedling (not for needle injection).

Packaging

  • Box containing 3 x 5 ml pre-mixed vials of Purasomes NC150+ Skin Nutri Complex.
  • Vials for topical use in combination with microneedling pen or similar in-clinic devices.
  • Professional packaging with batch number, expiry date and product identification for traceability.

Usage

  • For professional use only; treatment must be carried out by trained medical or aesthetic practitioners experienced in microneedling and regenerative therapies.
  • Assess the patient’s skin type, degree of ageing/photoageing and medical history to confirm suitability for exosome-based microneedling treatments.
  • Cleanse the treatment area thoroughly and disinfect according to clinic protocol; ensure skin is free of makeup, oils and debris.
  • Using a suitable microneedling device (pen or stamp) set to an appropriate needle depth for the face or body region, create uniform micro-channels over the treatment area.
  • Apply Purasomes NC150+ Skin Nutri Complex evenly to the skin during or immediately after microneedling, working the solution into the micro-channels to enhance penetration.
  • Gently massage any residual product into the skin until absorbed, avoiding excessive pressure or trauma.
  • A typical course consists of a series of 3–5 treatments spaced approximately every 4 weeks, adjusted according to clinical response and severity of ageing.
  • Advise patients to avoid direct sun exposure during the healing phase and to apply broad-spectrum sunscreen regularly; recommend gentle skincare and avoidance of irritating actives for several days post-treatment.
  • Purasomes NC150+ can be used as a standalone microneedling treatment, as a primer before energy-based treatments, as a recovery aid afterwards, or in combination with polynucleotides to maximise regenerative outcomes.
  • Follow manufacturer instructions for use (IFU) for detailed device settings, volumes per session and combination protocols.

Contraindications

  • Known hypersensitivity or allergy to any component of the formulation (e.g. hyaluronic acid, amino acids, vitamins, coenzymes, bovine-derived exosomes or PDRN/polynucleotides).
  • Active skin infections (bacterial, viral or fungal), open wounds or unhealed lesions in the proposed treatment area.
  • Inflammatory skin disorders or flares (e.g. active eczema, psoriasis, severe rosacea) in the target area where microneedling is contraindicated.
  • History of keloid or hypertrophic scarring where microneedling and regenerative stimulation are considered high risk by the treating physician.
  • Use of systemic isotretinoin within a time frame contraindicated for microneedling or resurfacing procedures, according to current guidelines.
  • Severe uncontrolled systemic disease, immunosuppression or active malignancy involving the skin being treated, where regenerative treatments are contraindicated.
  • Patients on anticoagulant or antiplatelet therapy with a bleeding risk deemed unacceptable for microneedling by the clinician.
  • Pregnancy and breastfeeding unless a suitably qualified clinician decides otherwise in line with local regulations and current evidence.
  • Any general contraindication to microneedling or exosome/polynucleotide-based treatments identified during medical assessment.

Adverse Effects

  • Expected transient effects related to microneedling such as erythema, mild oedema, warmth, tightness and pinpoint bleeding immediately post-treatment.
  • Short-lived dryness, flaking or sensitivity as the skin heals, particularly if aftercare instructions are not strictly followed.
  • Rare risk of infection if aseptic technique is inadequate or if patients pick or scratch at the treated area during healing.
  • Potential for post-inflammatory hyperpigmentation or, less commonly, hypopigmentation, especially in darker skin phototypes or with excessive inflammation and inadequate photoprotection.
  • Uncommon allergic or idiosyncratic reactions to one or more components of the complex (e.g. bovine-derived exosomes, PDRN, vitamins or excipients).
  • Very rare risk of prolonged redness, irritation or textural changes if treatment protocols are not adhered to or if performed on contraindicated skin.

Storage Conditions

  • Store vials in their original packaging in a cool, dry place at controlled room temperature as specified by the manufacturer.
  • Protect from direct sunlight, heat sources and freezing temperatures.
  • Keep vials upright and tightly closed until use; do not use if packaging, vial integrity or solution appearance is compromised.
  • Use each vial for a single patient according to local infection control policy and do not reuse any remaining product between patients.
  • Keep out of reach of children and unauthorised persons; for professional use only.

Duration

Each microneedling session with Purasomes NC150+ typically lasts around 20\u201340 minutes depending on the size of the treatment area. A standard protocol involves 3\u20135 sessions performed every four weeks, with clinical improvements in thickness, brightness, hydration and elasticity generally evident within four weeks and increasing over the full treatment course. Maintenance treatments may be scheduled according to individual patient needs.

Onset

Noticeable improvements in skin radiance and hydration often appear within weeks, with clinically documented increases in thickness, brightness, hydration and elasticity occurring in as little as four weeks. Structural benefits such as enhanced density, firmness and reduction in fine lines and wrinkles continue to develop over subsequent treatment sessions and skin remodelling cycles.

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