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Acnecide BOP 5% Gel 30g

Acnecide BOP 5% Gel 30g

Acnecide

Topical acne medicine (Pharmacy medicine)
  • Acnecide 5% w/w Gel is a licensed medicinal product in the UK with marketing authorisation number PL 10590/0006 held by Galderma (U.K.) Limited.
  • Classified as a Pharmacy Only medicine (P) for topical treatment of acne; supply is subject to pharmacist supervision and national medicines regulations.
  • Product information (SmPC and PIL) is approved by the UK Medicines and Healthcare products Regulatory Agency (MHRA) and published on the electronic medicines compendium (emc) and equivalent regulatory platforms.
  • Manufactured in accordance with EU/UK Good Manufacturing Practice (GMP) requirements for medicinal products.
  • Subject to ongoing post Marketing safety monitoring via national pharmacovigilance systems such as the MHRA Yellow Card scheme.
Leave-on benzoyl peroxide 5% w/w anti-acne gel

Description

Acnecide BOP 5% Gel 30g is a licensed topical anti-acne medicine containing 5% w/w benzoyl peroxide, supplied by DD Group within its facial aesthetics and cosmeceuticals range. It is a leave-on medicinal gel indicated for the treatment of acne vulgaris, particularly mild to moderate acne on the face, chest or back. The formulation combines benzoyl peroxide, which kills Cutibacterium acnes (formerly Propionibacterium acnes) – one of the main causes of acne – with an acrylates copolymer microsphere technology that helps absorb excess sebum while releasing glycerol to hydrate and moisturise the skin. When used as directed, Acnecide 5% Gel helps to reduce spot-causing bacteria by up to 95% within one week, unblock pores, reduce blackheads and whiteheads, and improve the overall appearance of spot-prone skin.

Bnefits

  • Leave-on daily treatment gel for mild to moderate acne on the face, chest or back.
  • Contains 5% w/w benzoyl peroxide, a well-established topical anti-acne agent that kills Cutibacterium acnes, a key bacteria involved in acne.
  • Clinically shown in product literature to reduce spot-causing bacteria by up to 95% within one week when used as directed.
  • Helps to unblock pores, reduce blackheads and whiteheads, and prevent new spots from forming.
  • Formulated with acrylates copolymer microsphere technology that absorbs excess oil and gradually releases glycerol to help soothe, hydrate and moisturise the skin.
  • Available as a smooth white to off-white gel that is easy to apply and suitable for targeted treatment of smaller acne-prone areas.
  • Licensed medicinal product with MHRA-approved SmPC and PIL, manufactured and marketed by Galderma (U.K.) Limited.
  • Minimal systemic absorption when used topically; acts primarily at the surface of the skin.

Indications

  • Cutaneous treatment of acne vulgaris where comedones (blackheads and whiteheads), papules and pustules predominate.
  • Mild to moderate acne on the face, chest or back in adults and adolescents aged 12 years and over.
  • Management of spot-prone skin to reduce the number and severity of inflammatory and non-inflammatory acne lesions.

Composition

  • Active substance: Hydrous benzoyl peroxide equivalent to benzoyl peroxide 5% w/w.
  • Excipients (as listed in Acnecide 5% w/w Gel / Acnecide Face 5% w/w Gel SmPCs and PILs): docusate sodium, disodium edetate, poloxamer 182, carbomer 940, propylene glycol (E1520), acrylates copolymer or glycerol microsponge, glycerol, colloidal anhydrous silica, sodium hydroxide (for pH adjustment), purified water.
  • Benzoyl peroxide is a keratolytic and antibacterial agent that helps reduce follicular plugging and kills acne-causing bacteria on the skin.

Formulation

  • Pharmaceutical form: gel for cutaneous use.
  • Appearance: white to off-white smooth gel.
  • Strength: 5% w/w benzoyl peroxide (50 mg benzoyl peroxide per gram of gel).
  • Pharmacotherapeutic group: anti-acne preparations for topical use, ATC code D10AE01.
  • Pack sizes in SmPC: 15 g, 30 g and 60 g polyethylene tubes (not all pack sizes may be marketed); the DD Group BOP presentation is a 30 g tube.

Packaging

  • White low-density polyethylene tube containing 30 g of Acnecide 5% w/w Gel, with screw cap (as per SmPC for Acnecide 5% w/w Gel pack sizes).
  • Outer carton (branded Acnecide) containing the tube and a Patient Information Leaflet with full directions for use, safety information and ingredients.
  • DD Group lists the product under facial aesthetics / cosmeceuticals with product code 620615 (Acnecide BOP 5% Gel 30g).

Usage

  • For cutaneous use only. Do not swallow. Avoid contact with eyes, mouth, angles of the nose, mucous membranes and broken or eczematous skin.
  • Adults and adolescents aged 12 years and over: after washing the affected area with a mild cleanser and water and gently patting dry, apply a thin layer of gel once daily to the entire affected area.
  • If tolerated after several days of once-daily use, the frequency can be increased to twice daily (morning and evening) as advised by a healthcare professional or according to the PIL.
  • People with sensitive skin are advised to start with once-daily application (preferably in the evening); if excessive dryness, redness, or irritation occurs, reduce frequency or temporarily stop treatment until the skin recovers.
  • Wash hands thoroughly before and after application. Avoid contact with hair and coloured fabrics, as benzoyl peroxide may bleach hair, clothing, towels and bedding.
  • Do not use concurrently with other topical products that have strong peeling, irritant or drying effects, or with additional benzoyl peroxide-containing preparations, unless directed by a doctor or pharmacist.
  • If accidental contact with eyes or mucous membranes occurs, rinse thoroughly with plenty of water and seek medical advice if irritation persists.
  • If acne does not improve within 12 weeks, or if it worsens, a doctor or pharmacist should be consulted for further management.

Contraindications

  • Known hypersensitivity (allergy) to benzoyl peroxide or to any of the excipients listed in the product information.
  • Should not be applied to damaged, broken, sunburnt or eczematous skin.
  • Use in children under 12 years of age is not recommended.
  • Do not use simultaneously with other benzoyl peroxide-containing products or other topical acne preparations with strong peeling, irritant or drying effects unless under medical supervision.

Adverse Effects

  • Very common/common: dry skin, redness (erythema), peeling, burning or stinging sensation at the application site, particularly at the start of treatment.
  • Uncommon: itching (pruritus), contact dermatitis, skin irritation or swelling at the application site.
  • Rare: allergic reactions including severe skin irritation, swelling or blistering; if signs of a severe allergic reaction (such as widespread rash, facial/lip swelling or difficulty breathing) occur, treatment should be stopped and urgent medical attention sought.
  • Benzoyl peroxide may increase skin sensitivity to sunlight and UV light; photosensitivity reactions (such as sunburn) can occur if adequate protection is not used.
  • In case of marked irritation, frequency of application should be reduced, treatment paused temporarily, or discontinued according to medical advice.

Storage Conditions

  • Do not store above 25°C.
  • Do not freeze.
  • Store in the original container and keep the tube tightly closed when not in use.
  • Keep out of the sight and reach of children.
  • Shelf life stated in the SmPC for Acnecide 5% w/w Gel is typically 2 years; users should check the expiry date on the tube and carton.

Duration

Visible improvement may take several weeks of regular use; many patients require continuous treatment for at least 4\u20136 weeks before a clear response is seen, and therapy may need to continue for several months as directed by a doctor or pharmacist. If there is no improvement after 12 weeks of appropriately used treatment, medical advice should be sought.

Onset

Not publicly listed (patient information and SmPC describe reductions in spot-causing bacteria within approximately 1 week and clinical improvement over several weeks, but do not provide a precise, standardised onset-of-action time).

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