CE Marked injectable medical device (Class III, per manufacturer/injectable classification)
Manufactured under sterile conditions by Croma Pharma GmbH (European pharmaceutical standards)
Intended for use by licensed medical professionals only
Supplied with sterile needles and instructions for safe use and disposal
CE Marked injectable medical device (Class III, per manufacturer/injectable classification)
Manufactured under sterile conditions by Croma Pharma GmbH (European pharmaceutical standards)
Intended for use by licensed medical professionals only
Supplied with sterile needles and instructions for safe use and disposal
Skin-booster / biostimulatory injectable
Description
PhilArt Next is an injectable skin-booster combining highly purified polynucleotides (PN-HPT) with non-crosslinked hyaluronic acid, intended for intradermal administration to rejuvenate and hydrate skin, stimulate collagen and elastin production and improve skin quality, firmness and elasticity. It is aimed at mature, dehydrated and ageing skin, as well as for improving skin tone, texture, scars or acne marks.
Bnefits
Stimulates fibroblast activity to boost collagen and elastin production and support skin structural renewal
Deeply hydrates skin thanks to hyaluronic acid content, improving moisture, softness and plumpness
Improves skin elasticity, firmness and tone — reducing the appearance of wrinkles and fine lines
Enhances skin texture, smoothness and radiance; improves overall skin quality
May improve appearance of scars and acne-related skin depressions or irregularities
Suitable for mature, dehydrated or damaged skin needing rejuvenation
Can be applied on face, neck, décolletage, hands (and sometimes scars/stretch-marks), depending on clinician protocol
Non-crosslinked and highly purified formulation to maximize biocompatibility and minimize risk of adverse reactions
Indications
Signs of skin ageing (loss of elasticity, wrinkles, fine lines)
Dehydrated skin lacking moisture and plumpness
Loss of skin firmness and tone
Uneven skin texture or dullness
Scars or acne-related skin irregularities or depressions
Skin quality improvement for mature or photo-aged skin
Skin rejuvenation for face, mid-face, neck, décolletage, hands (depending on practitioner protocol)
Composition
Polynucleotides (PN-HPT®) 20 mg / 2 ml
Non-crosslinked Hyaluronic Acid 20 mg / 2 ml
Formulation
Pre-filled 2 ml syringe of injectable gel/solution (dermis-appropriate viscosity)
Non-crosslinked hyaluronic acid plus polynucleotide biostimulant blend
Sterile injectable for intradermal use (microdroplet, linear or fan injection techniques)
Intended for professional use only (aesthetic/dermatology clinician administered)
Packaging
1 × 2 ml pre-filled sterile syringe
Includes 2 sterile needles (typically 30G ½, 13 mm) for injection
Secondary carton/box with product labeling, instructions for professional use and regulatory information (varies by distributor/market)
Usage
For professional intradermal injection only, administered by qualified aesthetic practitioner or dermatologist
Injection techniques: micro-droplets, linear or fanning, depending on area treated
Typical treatment course: 3 to 4 sessions spaced 14–21 days apart (for normal or mature skin depending on protocol)
Maintenance sessions may be scheduled every 4–6 months, or per clinician recommendation
Common treatment areas: face, mid-face, neck, décolletage, hands; may also address scars or acne marks as per practitioner’s plan
Post-treatment care as per clinician guidelines (e.g. avoid strenuous exercise, sun exposure, heavy skin-irritating products shortly after injection) — follow professional aftercare protocol
Contraindications
Known allergy or hypersensitivity to any component (polynucleotides, hyaluronic acid, excipients)
Active skin infection or inflammation at the intended injection site
Autoimmune disorders or immunocompromised states (consult clinician)
Pregnancy or breastfeeding (per many manufacturers’ recommended contraindications)
Use only by trained, licensed medical professionals — not for self-injection or unlicensed use
Adverse Effects
Transient local reactions: redness, swelling, bruising or mild pain at injection site
Possible mild itching or discomfort, transient and typically resolving in a few days
Rare risk of allergic reaction or hypersensitivity (depending on individual), so patient history must be reviewed
Risk of infection if aseptic technique not strictly followed; requires full professional sterile protocol
Temporary tenderness or sensitivity at injection sites, generally subsiding within a few days
Storage Conditions
Store unopened product in original packaging under recommended temperature conditions (typically between 2°C and 25°C), avoiding freezing or excessive heat
Protect from direct sunlight and contamination
Keep sterile until use; do not reuse syringe or needles; discard according to medical-waste guidelines after single-use
Store out of reach of unauthorized persons and children
Duration
Initial course of 3\u20134 sessions (over approx. 4\u20138 weeks), with maintenance every 4\u20136 months or as advised by treating clinician
Onset
Initial hydration and improved skin softness may be noticeable within days; cumulative improvements in elasticity, texture, firmness and reduction of fine lines typically observed over weeks to months following successive treatments
