Elaxen PN 3 x 2.5ml Skin Booster

Elaxen PN

Injectable skin booster

Polynucleotide (PN) biorevitalising skin booster

MFDS (Korean Ministry of Food and Drug Safety) certified bioregenerative polynucleotide solution for skin regeneration, as stated by multiple distributors
Manufactured under GMP (Good Manufacturing Practice) conditions by BNC Global in South Korea
Promoted by some distributors alongside CE/MFDS product group claims; practitioners should confirm local device classification and regulatory status from packaging and official documentation before use
Intended for professional injectable use only in accordance with local medical device and aesthetic practice regulations

MFDS (Korean Ministry of Food and Drug Safety) certified bioregenerative polynucleotide solution for skin regeneration, as stated by multiple distributors
Manufactured under GMP (Good Manufacturing Practice) conditions by BNC Global in South Korea
Promoted by some distributors alongside CE/MFDS product group claims; practitioners should confirm local device classification and regulatory status from packaging and official documentation before use
Intended for professional injectable use only in accordance with local medical device and aesthetic practice regulations

Polynucleotide (PN) biorevitalising skin booster

Description

Elaxen PN 3 x 2.5ml is an advanced polynucleotide-based skin booster developed by BNC Global in South Korea. Each professional set contains three pre-filled 2.5 ml syringes of highly purified salmon-derived polynucleotides (PN) at 20 mg/ml. Designed as a biorevitalizant for the prevention of ageing and skin rejuvenation, Elaxen PN works at the cellular level to stimulate tissue regeneration, enhance collagen and elastin synthesis, and strengthen the skin barrier. Clinical and in-vitro data from distributors report improvements in skin density, elasticity and hydration, with visible rejuvenation after a course of three treatments. The product is MFDS-certified in Korea and widely used as a non-surgical injectable treatment for dull, dehydrated, or ageing skin on the face, neck, and décolletage.

Bnefits

Deeply hydrates the skin and improves moisture retention in the epidermis and dermis
Enhances skin elasticity and firmness by stimulating collagen and elastin synthesis
Improves skin density and thickness for a more resilient, youthful appearance
Reduces the appearance of fine lines and wrinkles and helps refine pores
Strengthens and repairs the skin barrier, supporting long-term skin health
Evens skin tone and improves overall texture and radiance
Stimulates cellular repair and tissue regeneration at the dermal level
Provides long-lasting rejuvenation, with results commonly reported to last 6 months or more after a full course
High biocompatibility due to >95% human gene similarity of salmon-derived polynucleotides
MFDS-certified formula manufactured under GMP standards for consistency and safety

Indications

Biorevitalisation and rejuvenation of ageing, photo-damaged or stressed skin
Dull, dehydrated skin lacking elasticity and firmness
Fine lines, small wrinkles and early signs of skin ageing (temporal, periorbital and perioral areas)
Enlarged pores and uneven skin texture
Loss of skin density and compromised skin barrier function
Support of dermal tissue regeneration after superficial damage or procedures, as deemed appropriate by a clinician
Non-surgical anti-ageing protocols for face, neck and décolletage using injectable skin boosters

Composition

Polynucleotides (PN) 20 mg/ml (highly purified salmon-derived DNA fragments with >95% human gene similarity)
Hyaluronic acid (HA) – non-crosslinked, for deep hydration and improved elasticity
Glutathione – antioxidant to support brightening and protection against oxidative stress (reported in updated formulations)
Niacinamide (Vitamin B3) – supports barrier function and helps even skin tone (reported in multiple distributor ingredient lists)
Sodium chloride
Disodium phosphate
Sodium phosphate dihydrate
Water for injection

Formulation

Sterile, non-crosslinked polynucleotide gel solution for intradermal injection
Concentration: 20 mg/ml polynucleotides (50 mg PN per 2.5 ml syringe)
Total volume per box: 3 x 2.5 ml pre-filled syringes (7.5 ml total)
Source of PN: purified salmon germ cell DNA, >95% genetically similar to human DNA
Bio-regenerative, biocompatible solution manufactured under GMP and MFDS-certified conditions
Shelf life: typically 36 months from the date of manufacture (as stated by multiple distributors)

Packaging

Box containing 3 pre-filled sterile syringes, each 2.5 ml of Elaxen PN
Each syringe individually packaged in sterile blister or pouch
Outer carton labelled with product name, volume (2.5 ml x 3), main ingredient (PN), batch number and expiry date
Instructions for use / leaflet for professional users included in the box
Some distributors supply additional traceability labels for clinic and patient records

Usage

Elaxen PN is a prescription medical device/skin booster that must only be used by trained medical or aesthetic professionals familiar with injectable techniques and polynucleotide products.
Before use, check the integrity of the outer box and each sterile syringe pack; do not use if the packaging is damaged or past the expiry date.
Select an appropriate needle for the injection area (typically a fine mesotherapy needle such as 30–32G); attach under aseptic conditions.
Disinfect the treatment area thoroughly and allow to dry before injection.
Inject into the mid to lower dermis; the bevel of the needle should face upwards and the product must not be injected intravascularly.
Common treatment areas include the face (temporal, periorbital and perioral areas), neck and décolletage; injection patterns may include micro-bolus, nappage, or other mesotherapy techniques according to training and manufacturer protocols.
A typical treatment cycle consists of 3 procedures performed at 14-day intervals (every 2 weeks), using up to one 2.5 ml syringe per session depending on the treated area and practitioner protocol.
During injection, gently massage around the injection site as appropriate to distribute the product evenly while avoiding excessive pressure.
After treatment, advise the patient to avoid makeup on the treated area for at least 12–24 hours, and to avoid excessive sun/UV exposure, saunas, steam rooms, hot baths, swimming pools and intensive exercise for several days.
Used syringes and needles must be disposed of immediately in approved sharps containers; Elaxen PN is supplied as single-use only and must not be reused or re-sterilised.

Contraindications

Known hypersensitivity or allergy to polynucleotides, salmon-derived products or any excipient in the formulation
Enzyme intolerance related to fish (e.g. sturgeon/salmon) as noted by some distributors
Autoimmune diseases, unless the patient is specifically assessed and cleared by a physician with expertise in such conditions
Active fungal, bacterial or viral skin infections at or near the proposed injection sites
Pregnancy and breastfeeding
Acute respiratory or systemic illnesses (e.g. feverish conditions) at the time of treatment
Known tendency to develop hypertrophic scars or keloids in the treatment area
Bleeding disorders or current use of anticoagulants/antiplatelet agents where intradermal injections pose an unacceptable risk without specialist assessment
Any other condition in which injectable aesthetic treatments are deemed inappropriate by the treating clinician

Adverse Effects

Common, usually transient injection-site reactions such as redness (erythema), swelling, tenderness, mild pain, itching or a feeling of tightness
Small papules or nodules at injection points that typically resolve over hours to a few days
Minor bruising or haematoma at injection sites, especially in highly vascular areas or in patients on blood-thinning medications
Temporary worsening of dryness or sensitivity immediately post-procedure in some individuals before hydration improves
Rare local infections (e.g. cellulitis or abscess) if aseptic technique is not strictly followed, requiring medical treatment
Rare hypersensitivity or allergic-type reactions to polynucleotides or excipients, potentially including delayed inflammatory responses
Very rare but serious complications related to inadvertent intravascular injection or vascular compromise (e.g. tissue ischaemia or necrosis), which require immediate recognition and management in line with established filler/skin booster complication protocols

Storage Conditions

Store in a cool, dry place, typically between 1–30°C, protected from direct sunlight and heat sources (some distributors recommend refrigerated storage at 2–8°C; always follow the specific instructions on the product packaging).
Do not freeze the product.
Keep the syringes in their original outer carton until use to protect from light and contamination.
Store out of the reach of children and unauthorised persons.
Do not use after the expiry date printed on the packaging, or if individual sterile syringe packs are damaged or opened prior to use.

Duration

Standard protocols commonly recommend a course of 3 treatment sessions spaced 14 days apart. Visible rejuvenation is usually reported after completing the 3-session course, with results lasting around 6 months or more depending on age, skin condition, lifestyle and maintenance. Some practitioners repeat the course 1\u20132 times per year or schedule maintenance sessions every 6\u201312 months according to individual response.

Onset

Patients often notice improved hydration and skin radiance within the first few weeks of treatment, with more pronounced changes in elasticity, density, pore size and fine lines typically observed after 2\u20133 sessions (approximately 4\u20136 weeks from the start of the protocol).