Polynucleotide (PDRN) skin booster with hyaluronic acid and peptides for face, neck, d\u00e9colletage and hands
Certifications
Marketed in the UK and EU as a professional Use PN (PDRN) skin booster via licensed aesthetic wholesalers.
Manufactured under medical Aesthetic quality management systems; practitioners should verify CE/UKCA device marking and classification directly from packaging and the technical dossier.
Intended strictly for use by trained healthcare/aesthetic professionals in compliance with local regulations governing injectable aesthetic medical devices and skin boosters.
Marketed in the UK and EU as a professional Use PN (PDRN) skin booster via licensed aesthetic wholesalers.
Manufactured under medical Aesthetic quality management systems; practitioners should verify CE/UKCA device marking and classification directly from packaging and the technical dossier.
Intended strictly for use by trained healthcare/aesthetic professionals in compliance with local regulations governing injectable aesthetic medical devices and skin boosters.
Polynucleotide (PDRN) skin booster with hyaluronic acid and peptides for face, neck, d\u00e9colletage and hands
Description
Lumi-PN Face 1 x 2.5ml is an advanced polynucleotide (PN) injectable skin booster formulated to target global facial ageing and environmental damage. Each 2.5 ml pre-filled syringe contains 20 mg/ml of ultra-pure PDRN (polydeoxyribonucleotide) – delivering a total of 50 mg PN – combined with stabilised hyaluronic acid (HA) and rejuvenating peptides. Derived from purified salmon DNA, the polynucleotides support tissue regeneration, strengthen the skin barrier and stimulate fibroblast activity, encouraging new collagen and elastin production. Hyaluronic acid provides immediate and deep hydration for improved plumpness and texture, while bioactive peptides help smooth fine lines and reinforce dermal structure. The result is firmer, more elastic, hydrated and radiant skin across the face – and, in many protocols, the neck, décolletage and hands – with a healthier, more youthful glow.
Bnefits
Next-generation PN-based biostimulatory skin booster designed to combat multiple signs of ageing and photo-damage.
Delivers an industry-leading 50 mg of ultra-pure PDRN in a 2.5 ml syringe (20 mg/ml concentration) for powerful regenerative action.
Uses polynucleotides derived from purified salmon DNA to promote tissue repair, fibroblast activation and extracellular matrix renewal.
Global facial rejuvenation – improvement of texture, tone and hydration in ageing or environmentally damaged skin.
Dull, tired or dehydrated skin lacking radiance.
Fine lines and early to moderate wrinkles caused by intrinsic ageing or photodamage.
Mild to moderate skin laxity where enhanced elasticity and firmness are desired.
Compromised or weakened skin barrier requiring regenerative support and resilience.
Uneven texture or roughness across the face or other treatment areas such as neck, décolletage and hands (as per clinic protocol).
Adjunctive biostimulatory treatment alongside other aesthetic procedures (e.g. toxin, HA fillers, peels, RF, microneedling) as part of a comprehensive anti-ageing strategy.
Stabilised hyaluronic acid (HA) – concentration not publicly specified, included for hydration and dermal support.
Rejuvenating peptides – proprietary peptide complex aimed at boosting collagen/elastin and targeting fine lines (exact peptide list not fully disclosed).
Buffered aqueous solution with excipients such as sodium salts, pH adjusters and stabilisers (as detailed in the internal IFU/technical file).
No cross-linked HA gel – the product is a biostimulatory PN solution rather than a volumising dermal filler.
Concentration of PDRN: 20 mg/ml in a 2.5 ml pre-filled syringe (50 mg total).
Designed as a non-crosslinked PN skin booster for intradermal/mesotherapy or microneedling delivery.
Non-volumising formulation focused on hydration, regeneration and skin-quality improvement rather than structural augmentation.
Packaging
1 x 2.5 ml pre-filled sterile syringe of Lumi-PN Face per retail box.
Syringe supplied in a protective blister within branded outer carton.
Packaging marked with product name (Lumi-PN Face), volume (2.5 ml), PDRN content (50 mg, 20 mg/ml), batch/lot number, expiry date and manufacturer/distributor details.
Intended for single-patient professional use; syringe and residual product should not be reused or shared between patients.
Usage
For professional use only; must be administered by trained and appropriately qualified aesthetic/medical practitioners.
Typically delivered via superficial to mid-dermal injections (mesotherapy-style micro-bolus/serial puncture, nappage, micro-threading) or microneedling/electroporation protocols following official or clinic guidelines.
Common treatment areas include the full face, with optional extension to neck, décolletage and hands using appropriate depth and technique.
Before treatment, conduct a full medical history, skin assessment and informed consent; identify specific concerns (hydration, fine lines, tone, texture) and tailor the protocol accordingly.
Cleanse and disinfect the treatment area thoroughly; maintain strict aseptic technique, using sterile gloves, needles/cannulas and devices.
During injection, use small volumes per point and distribute product evenly over the chosen treatment field, avoiding intravascular injection and respecting anatomical safety zones.
Typical clinical courses may involve 2–4 sessions spaced approximately 2–4 weeks apart, depending on patient needs, skin status and practitioner protocol.
Post-treatment, advise patients to avoid makeup on treated areas for at least 12–24 hours, and to avoid strenuous exercise, alcohol, saunas/steam rooms and intense heat or sun exposure for 24–48 hours.
Daily broad-spectrum SPF use (SPF 30–50+) should be strongly recommended to protect the skin and maintain results.
Schedule follow-up appointments to evaluate response, adjust the treatment plan and arrange maintenance sessions if indicated.
Contraindications
Known hypersensitivity or allergy to polynucleotides/PDRN, hyaluronic acid, peptides or any excipients in the formulation.
Active skin infections, inflammations or lesions (e.g. bacterial, viral such as herpes simplex, fungal) at or near planned treatment sites.
History of severe allergic reactions, anaphylaxis or known hypersensitivity to injectable biostimulatory products.
Uncontrolled systemic disease, autoimmune disorders, significant immunosuppression or bleeding/coagulation disorders unless carefully evaluated and cleared by an appropriate clinician.
Pregnancy and breastfeeding, as elective aesthetic injectables are generally avoided due to limited safety data.
Recent procedures or implants in the treatment area that could interact adversely with PN injections (e.g. permanent fillers, certain threads), unless assessed by an experienced practitioner.
Any additional contraindications and cautions listed in the manufacturer’s instructions for use or required by local regulatory and professional guidelines for PN/skin booster injectables.
Adverse Effects
Common, self-limiting injection-related reactions: erythema (redness), mild swelling, tenderness, bruising, small haematomas and transient itching or warmth at injection sites.
Temporary papules or raised areas at injection points, especially with mesotherapy techniques; these typically resolve within hours to a few days as the solution disperses.
Rare inflammatory nodules or prolonged local reactions, which may require clinical evaluation and management.
Risk of infection at injection sites if aseptic technique or aftercare is inadequate, potentially presenting with increasing pain, redness, heat or discharge.
Very rare risk of intravascular injection and vascular compromise; practitioners must be trained to recognise early signs (severe pain, blanching, livedo, tissue changes) and initiate emergency protocols.
Hypersensitivity or allergic-type responses (e.g. swelling, persistent erythema, pruritus) to one or more components of the product, requiring prompt clinical assessment.
Patients should be instructed to contact the clinic urgently if they experience severe, escalating or unusual symptoms after treatment, including visual disturbance, significant asymmetry, persistent swelling or signs of infection.
Storage Conditions
Store Lumi-PN Face in its original packaging in a cool, dry place away from direct sunlight and heat sources.
Keep within the temperature range specified on the packaging (commonly 2–25°C); do not freeze.
Do not use if the blister, syringe or protective packaging is damaged or compromised.
Inspect visually before use; do not inject if the solution appears cloudy, discoloured or contains visible particulate matter.
Do not use beyond the expiry date printed on the carton and syringe.
Store out of reach of children and unauthorised persons, in line with clinic policies for injectable medical-aesthetic products.
Duration
Lumi-PN Face provides progressive regenerative effects rather than immediate volumetric change. Visible improvements in hydration and radiance are often reported after the first session, with more substantial changes in texture, firmness and fine lines developing gradually over a course of 2\u20134 treatments across several weeks. Depending on skin condition, lifestyle and age, results may be maintained for several months, and many practitioners recommend maintenance sessions every 6\u201312 months, although a specific duration claim is not formally standardised in public documentation.
Onset
Patients may notice increased hydration and a fresher look within days to a couple of weeks post-treatment. Collagen and elastin stimulation leads to further visible improvement in firmness, fine lines and overall skin quality over approximately 4\u20138 weeks, particularly after completing a multi-session protocol.
