CE marked for medical device / aesthetic use reported by manufacturer/distributors (verify CE certificate for specific SKU/batch)
Marketed for professional use in multiple international markets (regulatory status may vary by country)
CE marked for medical device / aesthetic use reported by manufacturer/distributors (verify CE certificate for specific SKU/batch)
Marketed for professional use in multiple international markets (regulatory status may vary by country)
Polynucleotide Scalp Injection / Hair Booster
Description
Nucleofill Medium Plus (Hair) is a polynucleotide-based injectable bio-revitalising gel formulated to strengthen hair follicles, improve scalp microcirculation and reduce hair loss (including androgenetic alopecia, postpartum thinning and support after transplant). Supplied as a sterile pre-filled syringe intended for professional intradermal/scalp microinjection.
Bnefits
Stimulates scalp microcirculation and angiogenesis to improve hair root nutrition
Strengthens hair follicles and reduces hair shedding
Supports tissue regeneration and antioxidant protection of the scalp
Useful as a standalone scalp rejuvenation treatment or adjunct to hair restoration protocols (e.g., PRP, transplant)
Supplied as ready-to-use prefilled syringe for professional administration
Indications
Androgenetic alopecia and other forms of hair thinning
Postpartum hair loss and temporary diffuse thinning
Supportive therapy pre- and post-hair transplant
Scalp revitalisation for weak/thinning hair and poor scalp quality
Composition
Active: Polymerised polynucleotides (polynucleotide DNA fragments) — distributor/manufacturer listings commonly state '20 mg/mL' or '20 mg per 2 mL' (sources vary; verify specific batch/IFU with supplier).
Sterile isotonic aqueous vehicle and excipients appropriate for intradermal injection (full INCI/IFU should be obtained from manufacturer/distributor).
For professional use only — administer by trained healthcare practitioners experienced in scalp injectable procedures.
Inject intradermally or superficially into the scalp using microinjection / mesotherapy / microdroplet technique as per manufacturer IFU and clinician judgement.
Typical protocols: series of sessions (commonly 2–4 or more) spaced 2–4 weeks apart, with maintenance treatments thereafter depending on response.
Follow aseptic technique; observe local aftercare guidance (avoid rubbing the area, high heat/sauna and strenuous exercise for 24–48 hours).
Contraindications
Active infection or inflammation at the intended injection site
Known hypersensitivity to any component of the product
Pregnancy and breastfeeding (use only after clinician risk–benefit assessment)
Patients with certain autoimmune diseases or uncontrolled systemic illness — assess case-by-case
Adverse Effects
Common (usually transient): local erythema, swelling, bruising, tenderness, small papules at injection sites
Less common/rare: infection, persistent nodules, hypersensitivity or allergic reactions
Technique-related complications (e.g., inadvertent intravascular injection) — mitigated by correct technique and practitioner training
Storage Conditions
Store in the original packaging at recommended temperatures per IFU (avoid freezing and excessive heat)
Protect from direct sunlight and keep out of reach of children
Check batch IFU for precise shelf-life/expiry information
Duration
Progressive improvement over weeks; treatment courses usually include multiple sessions and periodic maintenance \u2014 longevity varies by patient and protocol.
Onset
Early subjective improvements (scalp feel, hydration) may be noticed shortly after treatment; measurable improvements in shedding/hair density typically develop over several weeks to months.
