Aquashine BR Soft Filler Revofil (2x2ml)

Revofil

Injectable aesthetic medical device

Skin-brightening mesotherapy / dermal filler

CE Marked injectable product intended for intradermal use by healthcare professionals.
Manufactured under medical device quality management systems in accordance with applicable European regulations for injectable dermal/mesotherapy devices.

CE Marked injectable product intended for intradermal use by healthcare professionals.
Manufactured under medical device quality management systems in accordance with applicable European regulations for injectable dermal/mesotherapy devices.

Skin-brightening mesotherapy / dermal filler

Description

Aquashine BR Soft Filler Revofil (2x2ml) is a professional, sterile, injectable gel combining non-crosslinked hyaluronic acid (15 mg/ml) with a skin rejuvenating and brightening complex of peptides, amino acids, vitamins, minerals, coenzymes and nucleic acids. It is designed as a deep mesotherapy / biorevitalisation treatment for dull, uneven, photo-damaged skin with hyperpigmentation and fine lines. The BR (Brightening) version specifically targets skin tone irregularities and pigmentation while also hydrating, improving elasticity, tightening pores and softening wrinkles. Supplied as two pre-filled 2 ml syringes, it is intended for injection into the epidermis and superficial to mid dermis of the face, neck and décolletage by trained medical professionals only.

Bnefits

Brightens and evens skin tone by reducing hyperpigmentation and age-related discoloration.
Improves overall radiance and luminosity of dull, tired-looking skin.
Provides deep hydration through hyaluronic acid, improving elasticity and skin turgor.
Reduces fine lines and wrinkles while smoothing skin texture.
Tightens enlarged pores and helps reduce occasional breakouts associated with uneven texture.
Protects against photo-damage via an antioxidant complex of vitamins, minerals and coenzymes.
Peptide complex supports collagen and elastin synthesis for firmer, more resilient skin.
Revitalises photoaged skin and helps correct age-related skin changes.
Targets multiple concerns—tone, texture, hydration and elasticity—in a single treatment protocol.

Indications

Dull and uneven complexion.
Age-related pigmentation and various forms of hyperpigmentation, including age spots and sun spots.
Photo-damaged skin with loss of radiance.
Age-related skin changes, including decreased elasticity and fine lines.
Rosacea-prone skin and redness (as part of a broader rejuvenation protocol where appropriate).
Dilated pores and occasional breakouts.
Skin needing brightening, hydration and rejuvenation on the face, neck and décolletage.

Composition

Hyaluronic acid (1.5%) – sodium hyaluronate 15 mg/ml
Minerals and coenzymes: calcium chloride, magnesium sulfate, sodium chloride, sodium phosphate, thiamine diphosphate, coenzyme A, flavin adenine dinucleotide, nicotinamide adenine dinucleotide
Vitamins: A, B1, B2, B3, B5, B6, B7 (biotin), B8 (inositol), B9 (folic acid), B12, E, K1, C, PABA (para-aminobenzoic acid)
Amino acids: alanine, aminobutyric acid (GABA), arginine, asparagine, aspartic acid, cystine, glutamic acid, glutamine, glycine, histidine, hydroxyproline, isoleucine, leucine, lysine, methionine, ornithine, phenylalanine, proline, serine, taurine, threonine, valine
Nucleic acids and related nucleotides: adenosine phosphate, cytosine, guanosine, thymine phosphate (listed as thymopc)
Peptides: oligopeptide-34, oligopeptide-51, oligopeptide-23 (often listed as decapeptide-23), oligopeptide-72
Excipients: buffered solution components and stabilisers as per manufacturer’s formulation

Formulation

Transparent, sterile, non-pyrogenic injectable gel.
Non-crosslinked sodium hyaluronate (15 mg/ml) combined with a rejuvenating complex of 24 amino acids, 14 vitamins, 8 minerals, coenzymes, nucleic acids and 4 biomimetic peptides.
Designed as a combination mesotherapy / soft filler for skin revitalisation and brightening rather than volumising augmentation.
Viscoelastic properties optimised for superficial to mid-dermal injection and even distribution.
Single-use pre-filled syringes for professional injection only.

Packaging

Box containing 2 pre-filled 2 ml syringes (total 4 ml).
Each syringe is supplied in a sterile blister pack.
Typically supplied without needles; recommended needle size 32G 1/2".
Includes package insert with instructions for use and traceability stickers (depending on distributor presentation).

Usage

For professional use only; must be injected by a specialised doctor, dermatologist or aesthetic physician in a medical practice.
Indicated injection depth: epidermal and superficial to mid-dermal layers.
Injection areas: face, neck and décolletage (and other indicated areas according to clinical judgement).
Use appropriate mesotherapy / microinjection techniques (e.g. micro-papular, nappage, linear threading or serial puncture) with a 32G 1/2" needle or as per manufacturer guidance.
Typical treatment protocol: 3 sessions spaced approximately 4 weeks apart; maintenance sessions can be carried out based on clinical assessment.
Cleanse and disinfect the treatment area thoroughly; maintain strict aseptic technique throughout the procedure.
Inject small amounts per point, avoiding overcorrection; massage the treated area gently afterwards to ensure even distribution if required.
Do not inject into blood vessels, areas of active inflammation, infection or into compromised skin.
Advise patients on post-treatment care, including avoidance of excessive sun/UV exposure, saunas, extreme temperatures, vigorous exercise and makeup on the treated area for a specified period as per clinic protocol.
Always refer to the official product leaflet for detailed injection guidelines and contraindications.

Contraindications

Hypersensitivity or allergy to hyaluronic acid, peptides, amino acids, vitamins, minerals, nucleotides or any other component of the formulation.
Active skin infections, inflammatory lesions, herpetic eruptions or dermatologic disease at or near the intended injection sites.
History of severe allergies or anaphylactic reactions to injectable products.
Pregnancy or breastfeeding (elective aesthetic injections are generally contraindicated).
Autoimmune diseases or immunosuppression unless carefully evaluated and cleared by a physician.
Bleeding disorders or ongoing anticoagulant / antiplatelet therapy that significantly increases bleeding risk, unless managed under medical supervision.
Tendency to form hypertrophic scars or keloids.
Patients under 18 years of age.
Any other condition where injectable dermal/mesotherapy treatments are contraindicated according to current medical guidelines.

Adverse Effects

Common transient injection-site reactions such as redness, swelling, pain, tenderness, bruising and mild itching.
Temporary papules or small nodules at injection points, usually resolving spontaneously over several days.
Rare inflammatory reactions or more persistent nodules that may require medical assessment and treatment.
Potential allergic or hypersensitivity reactions to one or more components.
As with all injectable HA-based fillers and mesotherapy products, there is a small risk of infection, hematoma, vascular compromise or superficial necrosis if injected incorrectly or in high-risk areas.
Post-inflammatory hyperpigmentation may occur in predisposed individuals, particularly after inflammation or trauma in darker skin types.

Storage Conditions

Store in the original packaging to protect from light.
Keep at a controlled temperature as indicated in the product leaflet (typically between 2°C and 25°C); do not freeze.
Do not use after the expiry date stated on the packaging and syringes.
Single-use medical device: discard any remaining product after first use in accordance with local regulations for clinical waste.
Keep out of reach of children and unauthorised persons.

Duration

Typically administered as a course of 3 sessions at 4-week intervals. Clinical improvements in brightness, tone and texture may last several months; maintenance treatments can be performed periodically according to patient needs and practitioner judgement.

Onset

Initial improvement in hydration and luminosity is often visible shortly after treatment, with progressive brightening, evening of skin tone and softening of fine lines developing over the weeks following each session and across the full treatment course.